

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns |
Ingredients from packaging: ACTIVE INGREDIENTS: ALUMINUM ZIRCONIUM TETRACHLORHYDREX 20% GLY. INACTIVE INGREDIENTS: WATER, DIPROPYLENE GLYCOL, HYDROXYSTEARIC ACID, PEG-14 DIMETHICONE, CYCLOMETHICONE, AGAROSE, ACETAMIDE MEA, DIMETHICONE CROSSPOLYMER, DIVINYLDIMETHICONE/DIMETHICONE COPOLYMER, C12-13 PARETH-23, C12-13 PARETH-3.
Directions from packaging: Apply to underarms only. Cap tightly after use.
Warnings from packaging: + For external use only. + Do not use on broken skin. + Stop use if rash or irritation occurs. + Ask a doctor before use if you have kidney disease. + Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
| score | data gap | concerns | |
| PEG-14 DIMETHICONE | 4 | 75% | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| ALUMINUM ZIRCONIUM TETRACHLOROHYDREX GLYCINE COMPLEX ALUMINUM ZIRCONIUM TETRACHLORHYDREX GLY (Active Ingredient) | 1 | 91% | Organ system toxicity (non-reproductive) |
| CYCLOMETHICONE | 2 | 83% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| ACETAMIDE MEA | 1 | 73% | Contamination concerns (ACETAMIDE MEA) |
| HYDROXYSTEARIC ACID | 1 | 93% | none identified |
| C12-13 PARETH-23 | 1 | 86% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| C12-13 PARETH-3 | 1 | 86% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| DIPROPYLENE GLYCOL | 1 | 84% | Irritation (skin, eyes, or lungs) |
| DIMETHICONE CROSSPOLYMER | 0 | 100% | none identified |
| DIVINYLDIMETHICONE/ DIMETHICONE COPOLYMER | 0 | 100% | none identified |
| AGAROSE | 0 | 94% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at moderate doses | HYDROXYSTEARIC ACID |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PEG-14 DIMETHICONE, ACETAMIDE MEA |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | DIPROPYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | C12-13 PARETH-3, C12-13 PARETH-23 |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be persistent | C12-13 PARETH-3, C12-13 PARETH-23 | |
| Persistent, bioaccumulative in wildlife | CYCLOMETHICONE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | CYCLOMETHICONE, DIPROPYLENE GLYCOL, ACETAMIDE MEA | |
| One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient) | C12-13 PARETH-3, C12-13 PARETH-23 | |
| Limited evidence of sense organ toxicity | PEG-14 DIMETHICONE, ALUMINUM ZIRCONIUM TETRACHLOROHYDREX GLYCINE COMPLEX |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | C12-13 PARETH-3, CYCLOMETHICONE, C12-13 PARETH-23 |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | DIPROPYLENE GLYCOL |
| One or more animal studies show skin irritation at low doses | C12-13 PARETH-23, C12-13 PARETH-3 | |
| One or more animal studies show skin irritation at moderate doses | ACETAMIDE MEA, CYCLOMETHICONE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | PEG-14 DIMETHICONE, DIPROPYLENE GLYCOL | |
| Not assessed for safety in cosmetics by industry panel | C12-13 PARETH-3 | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | CYCLOMETHICONE | |
| Not assessed for safety in cosmetics by industry panel | DIVINYLDIMETHICONE/ DIMETHICONE COPOLYMER, DIMETHICONE CROSSPOLYMER, AGAROSE, ALUMINUM ZIRCONIUM TETRACHLOROHYDREX GLYCINE COMPLEX, C12-13 PARETH-23 |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CYCLOMETHICONE |
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