OPI Nail Envy Natural Nail Strengthener, Soft & Thin || Skin Deep: Cosmetic Safety Reviews

OPI NAIL ENVY NATURAL NAIL STRENGTHENER, SOFT & THIN

last updated: 10/01/09 brand: OPI by OPI Products

SCORE

high hazard (out of 10)

74%

data gap

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95% of nail polishs have lower concerns
90% of nail treatments have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Ethyl Acetate, Butyl Acetate, Nitrocellulose, Alcohol Denat. (SD alcohol 40B), Dibutyl Phthalate, Isopropyl Alcohol, Heptane, Tosylamide/Epoxy Resin, Acrylates Copolymer, Sucrose Acetate Isobutyate, Etocrylene, Formaldehyde, Calcium Pantothenate, Hydrolyzed Wheat Protein, Maris Sal (sea salt), Violet 2 (CI60725)

Directions from packaging: To strengthen soft and thin natural nails, apply two coats of Soft & Thin Nail Envy, followed by one coat every other day. Complete instructions enclosed.

Warnings from packaging: WarningsKeep out of reach of children. Keep away from heat and open flame.

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ingredients

	score	data gap	concerns
DIBUTYL PHTHALATE	10	49%	Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
FORMALDEHYDE	10	47%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
ETHYL ACETATE	4	78%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
D&C VIOLET 2 VIOLET 2 (CI60725)	2	71%	Cancer, Organ system toxicity (non-reproductive)
SD ALCOHOL 40B	4	81%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
SD ALCOHOL 1 ALCOHOL DENAT	4	77%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
ACRYLATES COPOLYMER	3	75%	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
SUCROSE ACETATE ISOBUTYRATE SUCROSE ACETATE ISOBUTYATE	1	86%	none identified
HEPTANE	2	75%	Irritation (skin, eyes, or lungs), Occupational hazards
HYDROLYZED WHEAT PROTEIN	1	95%	Allergies/immunotoxicity
NITROCELLULOSE	1	94%	Organ system toxicity (non-reproductive)
ETOCRYLENE	1	89%	Organ system toxicity (non-reproductive)
CALCIUM PANTOTHENATE	1	87%	none identified
BUTYL ACETATE	1	78%	Irritation (skin, eyes, or lungs), Occupational hazards
TOSYLAMIDE/ EPOXY RESIN	0	100%	none identified
SEA SALT	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		SEA SALT, ETHYL ACETATE
Cancer - not classifiable/not likely to be human carcinogen		HEPTANE, DIBUTYL PHTHALATE
Cancer - limited evidence		SD ALCOHOL 1, SD ALCOHOL 40B, D&C VIOLET 2
Cancer - not classifiable/not likely to be human carcinogen		ISOPROPYL ALCOHOL
Known human carcinogen		FORMALDEHYDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
One or more animal studies show reproductive effects at low doses		SEA SALT
Human nervous system toxicant - moderate evidence		ETHYL ACETATE, FORMALDEHYDE
Limited evidence of reproductive toxicity		SD ALCOHOL 1, SD ALCOHOL 40B
Possible human developmental toxicant		DIBUTYL PHTHALATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Recommendation to minimize use in cosmetics - Keep concentration to minimum: warning from industry safety panel		FORMALDEHYDE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ACRYLATES COPOLYMER, FORMALDEHYDE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		DIBUTYL PHTHALATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		FORMALDEHYDE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		SD ALCOHOL 1, SD ALCOHOL 40B, BUTYL ACETATE
One or more animal studies show brain and nervous system effects at high doses		SUCROSE ACETATE ISOBUTYRATE, FORMALDEHYDE
One or more animal studies show brain and nervous system effects at moderate doses		SEA SALT, CALCIUM PANTOTHENATE
Strong evidence of human neurotoxicity		ETHYL ACETATE, ISOPROPYL ALCOHOL, DIBUTYL PHTHALATE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		HEPTANE
Human any disruptor - strong evidence		DIBUTYL PHTHALATE
One or more animal studies show endocrine system disruption at high doses		SEA SALT

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		FORMALDEHYDE
One or more human case studies show possible skin allergy effects		HYDROLYZED WHEAT PROTEIN
Known human immune system toxicant		DIBUTYL PHTHALATE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		ISOPROPYL ALCOHOL, D&C VIOLET 2
Persistent, bioaccumulative in wildlife		DIBUTYL PHTHALATE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		NITROCELLULOSE, D&C VIOLET 2
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		HEPTANE, SUCROSE ACETATE ISOBUTYRATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		CALCIUM PANTOTHENATE
Limited evidence of sense organ toxicity		ISOPROPYL ALCOHOL, ETHYL ACETATE, SD ALCOHOL 1, SD ALCOHOL 40B
One or more animal studies show broad systemic effects at low doses		ETOCRYLENE
One or more animal studies show cardiovascular effects at very low doses		SEA SALT
Known human respiratory toxicant		FORMALDEHYDE, DIBUTYL PHTHALATE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		ISOPROPYL ALCOHOL, SEA SALT, SUCROSE ACETATE ISOBUTYRATE, FORMALDEHYDE, ETHYL ACETATE, CALCIUM PANTOTHENATE, BUTYL ACETATE
Used in food or as an additive with limited or no toxicity information available		SD ALCOHOL 40B, SD ALCOHOL 1

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be an environmental toxin		NITROCELLULOSE, ISOPROPYL ALCOHOL, D&C VIOLET 2
Wildlife and environmental toxicity		HEPTANE, DIBUTYL PHTHALATE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SUCROSE ACETATE ISOBUTYRATE
One or more animal studies show skin irritation at very low doses		SEA SALT
Human skin irritant - moderate evidence		FORMALDEHYDE
Classified as skin irritant	products for use on skin	BUTYL ACETATE
Classified as irritant		HEPTANE, ISOPROPYL ALCOHOL, ETHYL ACETATE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Considered safe based on assumption of low absorption		ACRYLATES COPOLYMER
Insufficient data to determine safety		HEPTANE, DIBUTYL PHTHALATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		SD ALCOHOL 1, SD ALCOHOL 40B, ETHYL ACETATE, DIBUTYL PHTHALATE, BUTYL ACETATE
Not assessed for safety in cosmetics by industry panel		HEPTANE, NITROCELLULOSE, SUCROSE ACETATE ISOBUTYRATE, TOSYLAMIDE/ EPOXY RESIN, CALCIUM PANTOTHENATE, ETOCRYLENE, HYDROLYZED WHEAT PROTEIN, ISOPROPYL ALCOHOL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to high doses		ISOPROPYL ALCOHOL, ETHYL ACETATE, BUTYL ACETATE
Allowed workplace exposures restricted to moderate doses		DIBUTYL PHTHALATE
Allowed workplace exposures restricted to low doses		HEPTANE, FORMALDEHYDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		FORMALDEHYDE, DIBUTYL PHTHALATE
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		SEA SALT