

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: WATER, AMODIMETHICONE, PANTHENOL, LACTAMIDOPROPYL TRIMONIUM CHLORIDE, GLYCERIN, TEA TREE OIL (MELALEUCA ALTERNIFOLIA), TOCOPHERYL ACETATE, NIACIN, SIMETHICONE, ASCORBYL PALMITATE, RETINYL PALMITATE, PYRIDOXINE HCL, FOLIC ACID, BIOTIN, CITRIC ACID, MAGNESIUM SULFATE, SACCHAROMYCES/ZINC FERMENT, SOYETHYL MORPHOLINIUM ETHOSULFATE, CETRIMONIUM CHLORIDE, POLYQUATERNIUM-11, POTASSIUM CHLORIDE, POLYSORBATE-20, FRAGRANCE, BENZOPHENONE-4, TRIDECETH-12, TETRASODIUM EDTA, METHYLPARABEN, DMDM HYDANTOIN
Directions from packaging: After shampooing, towel dry hair. Spray evenly to condition & detangle, and comb through. Do not rinse out. Style as usual.
| score | data gap | concerns | |
| DMDM HYDANTOIN | 7 | 61% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE) |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| METHYLPARABEN | 8 | 65% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| RETINYL PALMITATE | 5 | 70% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| TETRASODIUM EDTA | 1 | 80% | Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| FOLIC ACID | 4 | 79% | Developmental/reproductive toxicity, Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive) |
| CITRIC ACID | 4 | 72% | Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive) |
| SULISOBENZONE (BENZOPHENONE-4) (Active Ingredient) | 3 | 69% | Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| PYRIDOXINE HCL | 3 | 79% | Developmental/reproductive toxicity, Neurotoxicity |
| CETRIMONIUM CHLORIDE | 3 | 71% | Allergies/immunotoxicity |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| BIOTIN | 2 | 82% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive) |
| MAGNESIUM SULFATE | 2 | 82% | Organ system toxicity (non-reproductive) |
| POTASSIUM CHLORIDE | 2 | 82% | Neurotoxicity, Organ system toxicity (non-reproductive) |
| SACCHAROMYCES/ ZINC FERMENT | 2 | 81% | Allergies/immunotoxicity, Persistence and bioaccumulation |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| SOYAETHYL MORPHOLINIUM ETHOSULFATE SOYETHYL MORPHOLINIUM ETHOSULFATE | 0 | 94% | none identified |
| MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL TEA TREE OIL (MELALEUCA ALTERNIFOLIA) | 1 | 93% | Endocrine disruption, Allergies/immunotoxicity |
| ASCORBYL PALMITATE (VITAMIN C PALMITATE) | 1 | 88% | none identified |
| TRIDECETH-12 | 1 | 88% | none identified |
| NIACIN | 1 | 85% | none identified |
| POLYSORBATE-20 | 1 | 81% | none identified |
| LACTAMIDOPROPYL TRIMONIUM CHLORIDE | 0 | 100% | none identified |
| SIMETHICONE | 0 | 100% | none identified |
| AMODIMETHICONE | 0 | 99% | none identified |
| POLYQUATERNIUM-11 | 0 | 93% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not likely to be mutagenic in humans | SULISOBENZONE (BENZOPHENONE-4) | |
| One or more in vitro tests non-mammalian cells show positive mutation results | MAGNESIUM SULFATE | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, PYRIDOXINE HCL, POTASSIUM CHLORIDE, METHYLPARABEN, GLYCERIN, FOLIC ACID, CETRIMONIUM CHLORIDE | |
| Cancer - limited evidence | RETINYL PALMITATE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | POLYSORBATE-20, MAGNESIUM SULFATE | |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN | |
| One or more animal studies show reproductive effects at low doses | RETINYL PALMITATE, BIOTIN | |
| One or more animal studies show reproductive effects at very low doses | PYRIDOXINE HCL, FOLIC ACID |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | CETRIMONIUM CHLORIDE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | RETINYL PALMITATE, CITRIC ACID, DMDM HYDANTOIN, DMDM HYDANTOIN | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | RETINYL PALMITATE, NIACIN, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at moderate doses | METHYLPARABEN, MAGNESIUM SULFATE | |
| One or more animal studies show brain and nervous system effects at low doses | PYRIDOXINE HCL, POTASSIUM CHLORIDE, BIOTIN | |
| One or more animal studies show brain and nervous system effects at very low doses | FOLIC ACID, CITRIC ACID | |
| Moderate evidence of human neurotoxicity | FRAGRANCE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Associated with endocrine disruption | SULISOBENZONE (BENZOPHENONE-4) | |
| One or more animal studies show endocrine system disruption at high doses | PYRIDOXINE HCL, POTASSIUM CHLORIDE, POLYSORBATE-20, GLYCERIN | |
| One or more studies show weak endocrine disruption | METHYLPARABEN | |
| Limited evidence of any disruption | MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL | |
| One or more studies show endocrine system disruption at very low doses | FOLIC ACID |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of any toxicity | MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL | |
| Limited evidence of immune system toxicity | SACCHAROMYCES/ ZINC FERMENT | |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE, SULISOBENZONE (BENZOPHENONE-4), METHYLPARABEN, CETRIMONIUM CHLORIDE | |
| Known human immune system toxicant | FRAGRANCE, DMDM HYDANTOIN |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Persistent, bioaccumulative in wildlife | SACCHAROMYCES/ ZINC FERMENT |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | TRIDECETH-12, POLYSORBATE-20, PANTHENOL, ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| One or more animal studies show sense effects at moderate doses (low dose studies may be unavailable for this ingredient) | SULISOBENZONE (BENZOPHENONE-4) | |
| One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient) | PYRIDOXINE HCL, TETRASODIUM EDTA, | |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | SACCHAROMYCES/ ZINC FERMENT | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | TOCOPHERYL ACETATE, NIACIN, DMDM HYDANTOIN, CETRIMONIUM CHLORIDE | |
| Limited evidence of skin toxicity | RETINYL PALMITATE | |
| One or more animal studies show broad systemic effects at low doses | POTASSIUM CHLORIDE, BIOTIN | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, CITRIC ACID, MAGNESIUM SULFATE, FOLIC ACID | |
| Known human any toxicant | METHYLPARABEN |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TOCOPHERYL ACETATE, TETRASODIUM EDTA, RETINYL PALMITATE, PYRIDOXINE HCL, POTASSIUM CHLORIDE, POLYSORBATE-20, NIACIN, METHYLPARABEN, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, MAGNESIUM SULFATE, GLYCERIN, FOLIC ACID, CITRIC ACID, BIOTIN, ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | TRIDECETH-12, POLYSORBATE-20, GLYCERIN, CITRIC ACID | |
| One or more animal studies show skin irritation at low doses | TETRASODIUM EDTA, METHYLPARABEN | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | SULISOBENZONE (BENZOPHENONE-4), DMDM HYDANTOIN |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | AMODIMETHICONE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOCOPHERYL ACETATE, TETRASODIUM EDTA, SULISOBENZONE (BENZOPHENONE-4), RETINYL PALMITATE, POLYSORBATE-20, POLYQUATERNIUM-11, PANTHENOL, NIACIN, METHYLPARABEN, DMDM HYDANTOIN, BIOTIN, ASCORBYL PALMITATE (VITAMIN C PALMITATE), AMODIMETHICONE | |
| Not assessed for safety in cosmetics by industry panel | TRIDECETH-12, SOYAETHYL MORPHOLINIUM ETHOSULFATE, SIMETHICONE, SACCHAROMYCES/ ZINC FERMENT, PYRIDOXINE HCL, POTASSIUM CHLORIDE, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, MAGNESIUM SULFATE, LACTAMIDOPROPYL TRIMONIUM CHLORIDE, GLYCERIN, FRAGRANCE, FOLIC ACID, CITRIC ACID |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN | |
| Allowed workplace exposures restricted to low doses | TETRASODIUM EDTA |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | NIACIN, MAGNESIUM SULFATE, GLYCERIN, FOLIC ACID, CITRIC ACID | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | PYRIDOXINE HCL | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | RETINYL PALMITATE | |
| Interferes with gene expresion | METHYLPARABEN |
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