B. Kamins, Chemist Bio-Maple day cream, SPF 15 || Skin Deep: Cosmetic Safety Reviews

B. KAMINS, CHEMIST BIO-MAPLE DAY CREAM, SPF 15

last updated: 10/01/09 brand: B. Kamins by Kamins Dermatologics

SCORE

	health hazard
	sun hazard

79%

data gap

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PRODUCT USES

facial moisturizer/treatment
sunscreen: moisturizer

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

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Sunscreen effectiveness* breakdown

MEDIUM	UVB sunburn protection
LOW	UVA protection
MEDIUM	sunscreen stability

*Note that the same active ingredient combination may score differently in two different products depending on the concentration of the ingredients and the mixture of inactive ingredients.

Active ingredient UV
blocking strength

Product total

OCTINOXATE (OCTYL METHOXYCINNAMATE) ( 7.0? %)

OXYBENZONE (BENZOPHENONE-3) ( 3.3? %)

We have had to assume the percentage of the active ingredients in this product. If you own this product and it has the percentages printed on the package, you can help us fill in this missing information.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Active Ingredients: Octylmethoxycinnamate, Benzophenone 3Inactive Ingredients: Water Purified, Glyceryl Stearate, Marine Protein, Butylene Glycol, Bio Maple Compound (Maple Isolate), Cetyl Alcohol, Ceteareth 12, Squalane, Coco Caprylate/Caprinate, Magnesium Aluminum Silicate, Cyclomethicone, Dimethicone Copolyol, Soya Sterol, Polysorbate 80, Phenoxyethanol, Methylparaben, Ethylparaben, Propylparaben, Butylparaben, Apricot Kernel Oil, Dimethylpolysiloxane, Tocopherol Acetate, Retinyl Palmitate, Disodium EDTA, Trolamine, Fragrance

Directions from packaging: For external use only. Avoid contact with eyes. Discontinue use if signs of irritation appear. Keep out of children's reach. Active ingredients: octyl methoxycinnamate 7% w/w, benzophenone-3 5% w/w

Warnings from packaging: Warnings:For external use only. Avoid contact with eyes. Discontinue use if signs of irritation appear. Keep out of children's reach. Active ingredients: octyl methoxycinnamate 7% w/w, benzophenone-3 5% w/w

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
OXYBENZONE (BENZOPHENONE-3) (Active Ingredient)	9	55%	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-12	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OCTINOXATE (OCTYL METHOXYCINNAMATE) (Active Ingredient)	6	65%	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
BUTYLPARABEN	6	79%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
TRIETHANOLAMINE TROLAMINE	6	58%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
RETINYL PALMITATE	5	68%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
MAGNESIUM ALUMINUM SILICATE	4	88%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
TOCOPHERYL ACETATE TOCOPHEROL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
DIMETHICONE	2	74%	Violations, restrictions & warnings
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
POLYSORBATE-80	2	80%	Developmental/reproductive toxicity
SQUALANE	1	93%	Irritation (skin, eyes, or lungs)
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
BUTYLENE GLYCOL	1	79%	Irritation (skin, eyes, or lungs)
ACER SACCHARUM (MAPLE) ISOLATE BIO MAPLE COMPOUND (MAPLE ISOLATE)	0	100%	none identified
COCO-CAPRYLATE/ CAPRATE COCO CAPRYLATE/CAPRINATE	0	100%	none identified
DIMETHYL POLYSILOXANE	0	100%	none identified
GLYCINE SOJA (SOYBEAN) STEROLS SOYA STEROL	0	100%	none identified
MARINE PROTEIN	0	100%	none identified
PRUNUS ARMENIACA (APRICOT) KERNEL OIL	0	94%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL, OXYBENZONE (BENZOPHENONE-3)
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHERYL ACETATE, PROPYLPARABEN, POLYSORBATE-80, METHYLPARABEN, ETHYLPARABEN, DISODIUM EDTA, BUTYLPARABEN
Cancer - limited evidence		RETINYL PALMITATE
Cancer - not classifiable/not likely to be human carcinogen		TRIETHANOLAMINE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		ETHYLPARABEN
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at high doses		DISODIUM EDTA, BUTYLENE GLYCOL
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE
One or more animal studies show reproductive effects at very low doses		POLYSORBATE-80
Human nervous system toxicant - moderate evidence		MAGNESIUM ALUMINUM SILICATE
One or more animal studies show any effects at very low doses		BUTYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		CETEARETH-12, TRIETHANOLAMINE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		RETINYL PALMITATE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		OXYBENZONE (BENZOPHENONE-3)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		PHENOXYETHANOL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		POLYSORBATE-80, RETINYL PALMITATE, OXYBENZONE (BENZOPHENONE-3), BUTYLENE GLYCOL
One or more animal studies show brain and nervous system effects at moderate doses		PHENOXYETHANOL, METHYLPARABEN
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA
One or more animal studies show brain and nervous system effects at moderate doses		CETEARETH-12
Strong evidence of human neurotoxicity		MAGNESIUM ALUMINUM SILICATE
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		TRIETHANOLAMINE, DISODIUM EDTA, BUTYLENE GLYCOL
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)
Human any disruptor - strong evidence		PROPYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), METHYLPARABEN, ETHYLPARABEN, BUTYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN
Known human immune system toxicant		TRIETHANOLAMINE
Human skin toxicant - strong evidence		ETHYLPARABEN, BUTYLPARABEN
Possible human photoallergenic toxicant		OXYBENZONE (BENZOPHENONE-3)
Known human immune system toxicant		FRAGRANCE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TRIETHANOLAMINE
Not suspected to be persistent		CETYL ALCOHOL
Ingredient is suspected or measured to accumulate in people		OXYBENZONE (BENZOPHENONE-3), OCTINOXATE (OCTYL METHOXYCINNAMATE)
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		POLYSORBATE-80,
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		CYCLOMETHICONE, CETYL ALCOHOL, BUTYLENE GLYCOL
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-12, PHENOXYETHANOL,
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		TOCOPHERYL ACETATE, GLYCERYL MONOSTEARATE
Limited evidence of skin toxicity		RETINYL PALMITATE, PROPYLPARABEN, ETHYLPARABEN, BUTYLPARABEN
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA
Limited evidence of any toxicity		MAGNESIUM ALUMINUM SILICATE
Possible human immune system toxicant		TRIETHANOLAMINE
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		CYCLOMETHICONE
Not suspected to be an environmental toxin		TRIETHANOLAMINE
Suspected to be an environmental toxin		CETYL ALCOHOL
Wildlife and environmental toxicity		OXYBENZONE (BENZOPHENONE-3), OCTINOXATE (OCTYL METHOXYCINNAMATE)
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show skin irritation at moderate doses		CYCLOMETHICONE, BUTYLPARABEN
One or more animal studies show skin irritation at low doses		SQUALANE, METHYLPARABEN, CETEARETH-12
One or more animal studies show skin irritation at very low doses		TRIETHANOLAMINE, CETYL ALCOHOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL
Classified as irritant		PHENOXYETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		OXYBENZONE (BENZOPHENONE-3), PHENOXYETHANOL, POLYSORBATE-80, METHYLPARABEN, TOCOPHERYL ACETATE, RETINYL PALMITATE, PROPYLPARABEN, MAGNESIUM ALUMINUM SILICATE, ETHYLPARABEN, GLYCERYL MONOSTEARATE, DIMETHICONE, DISODIUM EDTA, CYCLOMETHICONE, CETYL ALCOHOL, BUTYLPARABEN, BUTYLENE GLYCOL
Not assessed for safety in cosmetics by industry panel		SQUALANE, PRUNUS ARMENIACA (APRICOT) KERNEL OIL, MARINE PROTEIN, GLYCINE SOJA (SOYBEAN) STEROLS, FRAGRANCE, DIMETHYL POLYSILOXANE, COCO-CAPRYLATE/ CAPRATE, ACER SACCHARUM (MAPLE) ISOLATE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		PHENOXYETHANOL
Allowed workplace exposures restricted to moderate doses		TRIETHANOLAMINE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CYCLOMETHICONE
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OXYBENZONE (BENZOPHENONE-3), RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN