

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards |
Ingredients from packaging: Toluene, Butyl Acetate, Ethyl Acetate, Isopropyl Alcohol, Cellulose Acetate Butyrate, Tosylamide/Epoxy Resin, Diethyl Phthalate, Dimethicone
Directions from packaging: Apply one or two coats over ORLY nail lacquer.
| score | data gap | concerns | |
| TOLUENE | 10 | 54% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (BENZENE), Occupational hazards |
| DIETHYL PHTHALATE | 8 | 64% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| ETHYL ACETATE | 4 | 78% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| CELLULOSE ACETATE BUTYRATE | 1 | 94% | Organ system toxicity (non-reproductive) |
| BUTYL ACETATE | 1 | 78% | Irritation (skin, eyes, or lungs), Occupational hazards |
| TOSYLAMIDE/ EPOXY RESIN | 0 | 100% | none identified |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | ETHYL ACETATE | |
| Cancer - not classifiable/not likely to be human carcinogen | DIETHYL PHTHALATE | |
| Cancer - not classifiable/not likely to be human carcinogen | TOLUENE, ISOPROPYL ALCOHOL |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL | |
| Human nervous system toxicant - moderate evidence | ETHYL ACETATE | |
| Limited evidence of reproductive toxicity | DIETHYL PHTHALATE | |
| Possible human developmental toxicant | TOLUENE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Restrictions on impurities recommended by industry safety panel | TOLUENE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE | |
| Violation of industry recommendations - Unsafe for use in cosmetics | TOLUENE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | BUTYL ACETATE | |
| Strong evidence of human neurotoxicity | ETHYL ACETATE, TOLUENE, ISOPROPYL ALCOHOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | DIETHYL PHTHALATE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of immune system toxicity | TOLUENE | |
| Known human immune system toxicant | DIETHYL PHTHALATE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | TOLUENE, ISOPROPYL ALCOHOL |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of sense organ toxicity | ETHYL ACETATE | |
| Classified as expected to be toxic or harmful | CELLULOSE ACETATE BUTYRATE | |
| Limited evidence of sense organ toxicity | ISOPROPYL ALCOHOL, DIETHYL PHTHALATE | |
| Known human respiratory toxicant | TOLUENE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | CELLULOSE ACETATE BUTYRATE, ISOPROPYL ALCOHOL | |
| Wildlife and environmental toxicity | DIETHYL PHTHALATE, TOLUENE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | DIETHYL PHTHALATE | |
| Classified as skin irritant | products for use on skin | TOLUENE, BUTYL ACETATE |
| Classified as irritant | ISOPROPYL ALCOHOL, ETHYL ACETATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Insufficient data to determine safety | DIETHYL PHTHALATE, TOLUENE | |
| Safety assessment was based on related chemical | DIETHYL PHTHALATE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | ETHYL ACETATE, TOLUENE | |
| Considered safe based on assumption of low absorption | TOLUENE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DIMETHICONE, DIETHYL PHTHALATE, BUTYL ACETATE | |
| Not assessed for safety in cosmetics by industry panel | CELLULOSE ACETATE BUTYRATE, ISOPROPYL ALCOHOL, TOSYLAMIDE/ EPOXY RESIN |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | DIETHYL PHTHALATE | |
| Allowed workplace exposures restricted to high doses | ISOPROPYL ALCOHOL, BUTYL ACETATE, ETHYL ACETATE, TOLUENE |
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