

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: ACTIVE INGREDIENTS: SODIUM MONOFLUOROPHOSPHATE 0.13% W/V FLOURIDE ION (ANTICAVITY) INACTIVE INGREDIENTS: GLYCERIN, WATER, CALCIUM CARBONATE, HYDRATED SILICA, XYLITOL, CARRAGEENAN (CHONDRUS CRIPUS), SODIUM LAURYL SULFATE (DERIVED FROM COCONUT OIL), WINTERGREEN (GAULTHERIA PROCUMBENS), OTHER NATURAL FLAVORS
Directions from packaging: + Adults and children 2 years of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or doctor + Children under 6: Use a pea-sized amount + Instruct children under 6 years of age in good brushing and rinsing habits (to minimize swallowing) + Children under 2 years of age: Consult a dentist or doctor + Supervise children as necessary until capable of using without supervision
Warnings from packaging: + For external use only + Keep out of reach of children under 6 years of age + If more than one brushing is accidentally swallowed, seek professional help or contact a Poison Control Center right away
| score | data gap | concerns | |
| SODIUM MONOFLUOROPHOSPHATE (Active Ingredient) | 6 | 69% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| UNSPECIFIED FLAVOR OTHER NATURAL FLAVORS | 4 | 100% | Miscellaneous |
| CARRAGEENAN | 2 | 75% | Organ system toxicity (non-reproductive), Contamination concerns (DEGRADED CARRAGEENAN), Biochemical or cellular level changes |
| SODIUM LAURYL SULFATE | 3 | 68% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| HYDRATED SILICA | 2 | 79% | Persistence and bioaccumulation |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| GAULTHERIA PROCUMBENS (WINTERGREEN) LEAF EXTRACT WINTERGREEN (GAULTHERIA PROCUMBENS) | 1 | 100% | Multiple, additive exposure sources |
| XYLITOL | 1 | 88% | none identified |
| CALCIUM CARBONATE | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM MONOFLUOROPHOSPHATE, SODIUM LAURYL SULFATE, GLYCERIN | |
| Not likely to be carcinogenic in humans | CARRAGEENAN | |
| Cancer - not classifiable/not likely to be human carcinogen | HYDRATED SILICA |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN | |
| Human nervous system toxicant - moderate evidence | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SODIUM MONOFLUOROPHOSPHATE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAURYL SULFATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | XYLITOL, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM LAURYL SULFATE, CARRAGEENAN | |
| Strong evidence of human neurotoxicity | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | GLYCERIN, SODIUM LAURYL SULFATE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Persistent, bioaccumulative in wildlife and humans | HYDRATED SILICA | |
| Not suspected to be persistent | SODIUM LAURYL SULFATE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | XYLITOL | |
| One or more animal studies show broad systemic effects at low doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | CALCIUM CARBONATE |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, SODIUM MONOFLUOROPHOSPHATE, CARRAGEENAN |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | UNSPECIFIED FLAVOR |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | XYLITOL, SODIUM LAURYL SULFATE, GLYCERIN, CARRAGEENAN, CALCIUM CARBONATE | |
| Used in food or as an additive with limited or no toxicity information available | GAULTHERIA PROCUMBENS (WINTERGREEN) LEAF EXTRACT |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | SODIUM LAURYL SULFATE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | GLYCERIN | |
| One or more animal studies show skin irritation at low doses | CALCIUM CARBONATE | |
| One or more animal studies show skin irritation at very low doses | SODIUM LAURYL SULFATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not assessed for safety in cosmetics by industry panel | HYDRATED SILICA, GAULTHERIA PROCUMBENS (WINTERGREEN) LEAF EXTRACT, XYLITOL, UNSPECIFIED FLAVOR, SODIUM MONOFLUOROPHOSPHATE, GLYCERIN, CARRAGEENAN, CALCIUM CARBONATE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, CALCIUM CARBONATE | |
| Allowed workplace exposures restricted to low doses | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | XYLITOL, GLYCERIN | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | SODIUM LAURYL SULFATE | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | CARRAGEENAN |
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