

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Acrylates Copolymer, Benzoyl Peroxide - Completely Evaporates After Drying, Silica, Ethyl Methacrylate, HEMA, Glycol Dimethacrylate, Dimethyltolylamine, Benzophenone-3, P-Hydroxyanisole, CI 60725, CI 61565
Directions from packaging: Nail Prep:Clean nails thoroughly.Gently file area of new nail growth, blending with existing acrylic overlay.How to Apply:Dip brush into Acrylic Liquid and then into Acrylic Powder until a small acrylic bead forms at end of brush.Place acrylic bead at cuticle area covering new nail growth. Lightly pat down area where the bead meets existing acrylic overlay. Let dry.Using file, smooth new acrylic surface and shape nail as needed.How to Remove:Do not force or pull nails off. Trim off as much artificial nail as possible and file top of artificial nail surface.For quick, easy removal use artificial nail remover or soak nails in acetone-based nail polish remover until soft.Wipe off softened plastic and glue. Repeat process as necessary.When you are finished, clean bristles of acrylic brush using acetone-based nail polish remover.Be sure to store acrylic liquid and powder with container tops secured tightly.
Warnings from packaging: Irritant.Flammable.Eye irritant.If eye contact occurs, flush immediately with water and see physician at once.Avoid contact with fabrics.Use in a well-ventilated area.Avoid inhalation, ingestion, or prolonged contact with skin.Do not use on nails that are infected, damaged, thin or weak.Discontinue use if irritation, redness or discomfort occurs.Acrylic Liquid is flammable.Keep away from heat and flame.Store contents in dark, cool location.Keep out of reach of children.
| score | data gap | concerns | |
| OXYBENZONE (BENZOPHENONE-3) (Active Ingredient) | 9 | 55% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| HEMA | 8 | 59% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ETHYL METHACRYLATE | 8 | 57% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| SILICA | 1 | 69% | Biochemical or cellular level changes |
| HYDROXYANISOLE | 7 | 67% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| BENZOYL PEROXIDE | 7 | 55% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| CI 61565 | 4 | 75% | Violations, restrictions & warnings |
| CI 60725 | 4 | 73% | Violations, restrictions & warnings |
| ACRYLATES COPOLYMER | 3 | 75% | Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE) |
| DIMETHYLTOLYLAMINE | 2 | 83% | Organ system toxicity (non-reproductive), Occupational hazards |
| GLYCERYL POLYMETHACRYLATE GLYCOL DIMETHACRYLATE | 0 | 94% | none identified |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | CI 60725, OXYBENZONE (BENZOPHENONE-3) | |
| One or more in vitro tests on mammalian cells show positive mutation results | ETHYL METHACRYLATE, HEMA, DIMETHYLTOLYLAMINE, HYDROXYANISOLE | |
| Cancer - not classifiable/not likely to be human carcinogen | BENZOYL PEROXIDE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | BENZOYL PEROXIDE | |
| One or more animal studies show reproductive effects at high doses | HEMA, ETHYL METHACRYLATE | |
| Limited evidence of developmental toxicity | OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | HEMA | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | ETHYL METHACRYLATE, HYDROXYANISOLE, BENZOYL PEROXIDE, OXYBENZONE (BENZOPHENONE-3) | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Avoid skin contact | products for use on skin | HEMA, ETHYL METHACRYLATE |
| Violation of industry recommendations - Unsafe for use in cosmetics | HYDROXYANISOLE, HYDROXYANISOLE | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | CI 61565, CI 60725 | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | HEMA, ETHYL METHACRYLATE, ACRYLATES COPOLYMER |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | HEMA, ETHYL METHACRYLATE, OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - moderate evidence | OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin toxicant - strong evidence | HYDROXYANISOLE | |
| Limited evidence of immune system toxicity | BENZOYL PEROXIDE | |
| Known human immune system toxicant | ETHYL METHACRYLATE, HEMA | |
| Possible human photoallergenic toxicant | OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient is suspected or measured to accumulate in people | OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | SILICA | |
| Limited evidence of sense organ toxicity | HEMA | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | CI 60725, CI 61565, | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | OXYBENZONE (BENZOPHENONE-3) | |
| Possible human immune system toxicant | ETHYL METHACRYLATE | |
| One or more animal studies show liver effects at very low doses | HYDROXYANISOLE | |
| One or more animal studies show broad systemic effects at low doses | BENZOYL PEROXIDE | |
| Classified as toxic or harmful | products for use on skin; products for use around the mouth; products for use on the lips; products that may be aerosolized (airborne) | DIMETHYLTOLYLAMINE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | OXYBENZONE (BENZOPHENONE-3) | |
| Wildlife and environmental toxicity | DIMETHYLTOLYLAMINE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as irritant | HEMA | |
| One or more animal studies show skin irritation at very low doses | BENZOYL PEROXIDE | |
| Not likely to be a skin irritant in humans | OXYBENZONE (BENZOPHENONE-3) | |
| Classified as irritant | HYDROXYANISOLE, ETHYL METHACRYLATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Considered safe based on assumption of low absorption | ACRYLATES COPOLYMER | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | OXYBENZONE (BENZOPHENONE-3) | |
| Not assessed for safety in cosmetics by industry panel | GLYCERYL POLYMETHACRYLATE, CI 60725, DIMETHYLTOLYLAMINE, CI 61565, BENZOYL PEROXIDE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | DIMETHYLTOLYLAMINE, HYDROXYANISOLE | |
| Allowed workplace exposures restricted to very low doses | BENZOYL PEROXIDE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | HEMA | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SILICA, HYDROXYANISOLE |
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