OPI NATURAL NAIL BASE COAT (2006 FORMULATION)
last updated: 05/01/06 brand: OPI by OPI Products
COMPANY POLICIES
Compact for Safe Cosmetics
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Animal Testing Policy |
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards |
Ingredients from packaging: BUTYL ACETATE, TOLUENE, ETHYL ACETATE, ISOPROPYL ALCOHOL, TOSYLAMIDE/FORMALDEHYDE RESIN, POLYVINYL BUTYRAL, NITROCELLULOSE, CAMPHOR, BENZOPHENONE-1, ISOSTEAROYL HYDROLIZED PROTEIN, KERATIN AMINO ACIDS, CI 17200
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ingredients
| score | data gap | concerns | |
| TOLUENE | 10 | 54% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (BENZENE), Occupational hazards |
| BENZOPHENONE-1 | 5 | 79% | Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| ETHYL ACETATE | 4 | 78% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| TOSYLAMIDE/ FORMALDEHYDE RESIN | 4 | 72% | Allergies/immunotoxicity |
| CAMPHOR | 4 | 69% | Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| NITROCELLULOSE | 1 | 94% | Organ system toxicity (non-reproductive) |
| CI 17200 | 1 | 93% | none identified |
| POLYVINYL BUTYRAL | 0 | 89% | none identified |
| BUTYL ACETATE | 1 | 78% | Irritation (skin, eyes, or lungs), Occupational hazards |
| AMP ISOSTEAROYL HYDROLYZED WHEAT PROTEIN ISOSTEAROYL HYDROLIZED PROTEIN | 0 | 100% | none identified |
| KERATIN AMINO ACIDS | 0 | 100% | none identified |
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | CI 17200 | |
| One or more in vitro tests on mammalian cells show positive mutation results | CAMPHOR, ETHYL ACETATE | |
| Cancer - not classifiable/not likely to be human carcinogen | TOLUENE, ISOPROPYL ALCOHOL |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL | |
| Possible human developmental toxicant | TOLUENE | |
| Human nervous system toxicant - moderate evidence | ETHYL ACETATE |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Restrictions on impurities recommended by industry safety panel | TOLUENE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | CAMPHOR | |
| Violation of industry recommendations - Unsafe for use in cosmetics | TOLUENE |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | BUTYL ACETATE | |
| One or more animal studies show brain and nervous system effects at high doses | BENZOPHENONE-1 | |
| One or more animal studies show brain and nervous system effects at low doses | CAMPHOR | |
| Strong evidence of human neurotoxicity | ETHYL ACETATE, TOLUENE, ISOPROPYL ALCOHOL |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine disruption at moderate doses | BENZOPHENONE-1 |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of immune system toxicity | TOLUENE | |
| Human skin toxicant - strong evidence | BENZOPHENONE-1 | |
| Known human immune system toxicant | TOSYLAMIDE/ FORMALDEHYDE RESIN |
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of sense organ toxicity | ISOPROPYL ALCOHOL, ETHYL ACETATE | |
| One or more animal studies show gastrointestinal effects at low doses | CAMPHOR, BENZOPHENONE-1 | |
| Known human respiratory toxicant | TOLUENE |
Ecotoxicology*
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | TOLUENE |
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as skin irritant | products for use on skin | TOLUENE, BUTYL ACETATE |
| Classified as irritant | ISOPROPYL ALCOHOL, ETHYL ACETATE |
Data gaps*
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOLUENE, ETHYL ACETATE, BUTYL ACETATE, BENZOPHENONE-1 | |
| Not assessed for safety in cosmetics by industry panel | POLYVINYL BUTYRAL, CI 17200, NITROCELLULOSE, KERATIN AMINO ACIDS, ISOPROPYL ALCOHOL, CAMPHOR, AMP ISOSTEAROYL HYDROLYZED WHEAT PROTEIN | |
| Considered safe based on assumption of low absorption | TOLUENE | |
| Insufficient data to determine safety | TOLUENE |
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | CAMPHOR | |
| Allowed workplace exposures restricted to high doses | BUTYL ACETATE, ETHYL ACETATE, ISOPROPYL ALCOHOL, TOLUENE |
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