Olay Regenerist Advanced Anti-Aging UV Defense Regenerating Lotion, SPF 50 || Skin Deep: Cosmetic Safety Reviews

OLAY REGENERIST ADVANCED ANTI-AGING UV DEFENSE REGENERATING LOTION, SPF 50

last updated: 10/01/09 brand: Olay by Procter & Gamble

SCORE

	health hazard
	sun hazard

74%

data gap

Find Your Sunscreengreat free widgetsWidgetbox

PRODUCT USES

anti-aging
facial moisturizer/treatment
sunscreen: moisturizer

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Buy on Amazon, Support EWG!

Sunscreen effectiveness* breakdown

HIGH	UVB sunburn protection
MEDIUM	UVA protection
MEDIUM	sunscreen stability

*Note that the same active ingredient combination may score differently in two different products depending on the concentration of the ingredients and the mixture of inactive ingredients.

Active ingredient UV
blocking strength

Product total

HOMOSALATE (15%)

OXYBENZONE (BENZOPHENONE-3) (6%)

AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) (3%)

OCTOCRYLENE (2.7%)

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Active Ingredients: Homosalate (15.0%), Oxybenzone (6.0%), Avobenzone (3.0%), Octocrylene (2.7%)Inactive Ingredients: Water, Glycerin, Polymethylsilsesquioxane, Niacinamide, Polyethylene, Pentylene Glycol, Dimethicone, Panthenol (**), Palmitoyl Pentapeptide 4 (***), Carnosine (***)

Directions from packaging: Wet face. Dispense a small amount of product into hands. Add water and work into a lather, adding more water if necessary. Massage gently onto face and neck. Rinse thoroughly.

Warnings from packaging: WarningsFor external use only. Not to be swallowed. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

user reviews & comments

NEW! No reviews or ratings yet. Log in and be the first to leave a comment!

ingredients

	score	data gap	concerns
OXYBENZONE (BENZOPHENONE-3) (Active Ingredient)	9	55%	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
POLYETHYLENE	6	69%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
HOMOSALATE (Active Ingredient)	4	74%	Violations, restrictions & warnings, Enhanced skin absorption, Contamination concerns (SALICYLIC ACID, TRIMETHYLCYCLOHEXANOL)
DIMETHICONE	2	74%	Violations, restrictions & warnings
OCTOCRYLENE (Active Ingredient)	3	71%	Violations, restrictions & warnings, Biochemical or cellular level changes
PANTHENOL	2	88%	Multiple, additive exposure sources
NIACINAMIDE	2	81%	Organ system toxicity (non-reproductive), Biochemical or cellular level changes
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE) (Active Ingredient)	2	73%	Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE)
PENTYLENE GLYCOL	1	89%	none identified
CARNOSINE	1	85%	none identified
POLYMETHYLSILSESQUIOXANE	0	100%	none identified
PALMITOYL PENTAPEPTIDE-4	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		OXYBENZONE (BENZOPHENONE-3)
One or more in vitro tests on mammalian cells show positive mutation results		NIACINAMIDE, GLYCERIN,
One or more in vitro tests on mammalian cells show positive mutation results		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Cancer - not classifiable/not likely to be human carcinogen		POLYETHYLENE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at moderate doses		GLYCERIN
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show reproductive effects at moderate doses		CARNOSINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		POLYETHYLENE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		OXYBENZONE (BENZOPHENONE-3), HOMOSALATE, OCTOCRYLENE, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN, NIACINAMIDE, OXYBENZONE (BENZOPHENONE-3), PENTYLENE GLYCOL, POLYETHYLENE, CARNOSINE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		GLYCERIN
One or more animal studies show endocrine disruption at moderate doses		NIACINAMIDE
One or more studies show weak endocrine disruption		HOMOSALATE
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Possible human photoallergenic toxicant		OXYBENZONE (BENZOPHENONE-3)
Human immune system toxicant - moderate evidence		POLYETHYLENE
Associated with immunotoxicity		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient is suspected or measured to accumulate in people		OXYBENZONE (BENZOPHENONE-3)
Found to be persistent and bioaccumulative in wildlife		OCTOCRYLENE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		PANTHENOL, PENTYLENE GLYCOL, OCTOCRYLENE, CARNOSINE
Possible human immune system toxicant		POLYETHYLENE
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, NIACINAMIDE
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3)

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		DIMETHICONE, GLYCERIN, POLYETHYLENE, NIACINAMIDE
Used in food or as an additive with limited or no toxicity information available		PANTHENOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		OXYBENZONE (BENZOPHENONE-3), OCTOCRYLENE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show skin irritation at high doses		PENTYLENE GLYCOL
One or more animal studies show skin irritation at moderate doses		GLYCERIN
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	POLYETHYLENE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Missing safety data noted by cosmetic industry review		POLYETHYLENE
Considered safe based on assumption of low absorption		POLYETHYLENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		POLYETHYLENE, PANTHENOL, OXYBENZONE (BENZOPHENONE-3), NIACINAMIDE, DIMETHICONE
Not assessed for safety in cosmetics by industry panel		PALMITOYL PENTAPEPTIDE-4, POLYMETHYLSILSESQUIOXANE, OCTOCRYLENE, PENTYLENE GLYCOL, HOMOSALATE, GLYCERIN, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), CARNOSINE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		GLYCERIN

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OXYBENZONE (BENZOPHENONE-3), OCTOCRYLENE
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		NIACINAMIDE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		GLYCERIN, POLYETHYLENE