L'Oréal Couleur Experte Hair Color, 8.1 Tiramisu, Medium Ash Blonde, Cool (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

L'ORéAL COULEUR EXPERTE HAIR COLOR, 8.1 TIRAMISU, MEDIUM ASH BLONDE, COOL (2006 FORMULATION)

last updated: 05/01/06 brand: L'Oréal by L'Oréal

SCORE

high hazard (out of 10)

79%

data gap

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72% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: MULTI-TONAL GEL CREME: WATER; DECETH-3; LAURETH-12; OLETH-30; DECETH-5; TRIDECETH-2 CARBOXAMIDE MEA; AMMONIUM HYDROXIDE; GLYCERIN; OLEIC ACID; HEXADIMETHRINE CHLORIDE; OLEYL ALCOHOL; POLYQUATERNIUM-6; FRAGRANCE; P-AMINOPHENOL; P-PHENYLENEDIAMINE; ETHANOLAMINE; AMMONIUM THIOLACTATE; P-METHYLAMINOPHENOL SULFATE; ASCORBIC ACID; 4-AMINO-2-HYDROXYTOLUENE; EDTA; 2-METHYL-5-HYDROXYETHYLAMINOPHENOL; RESORCINOL; POLYQUATERNIUM-24; M-AMINOPHENOL; 2-METHYLRESORCINOL; 6-HYDROXYINDOLE. MICRO-FINE ILLUMINATING POWDER: POTASSIUM PERSULFATE; SODIUM SILICATE; SODIUM PERSULFATE; ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER; UREA; KAOLIN; MAGNESIUM STEARATE; AMMONIUM CHLORIDE; DIETHYLHEXYL SODIUM SULFOSUCCINATE; VP/VA COPOLYMER; POLYDECENE; SODIUM METASILICATE; MAGNESIUM PEROXIDE; EDTA; TITANIUM DIOXIDE; CYAMOPSIS TETRAGONOLOBA (GUAR) GUM; SODIUM CARBOXYMETHYL STARCH; SODIUM BENZOATE. MULTI-TONAL CREME DEVELOPER: WATER; HYDROGEN PEROXIDE; CETEARYL ALCOHOL; TRIDECETH-2-CARBOXAMIDE MEA; CETEARETH-30; GLYCERIN; PENTASODIUM PENTETATE; SODIUM STANNATE; TETRASODIUM PYROPHOSPHATE. ILLUMINATING CREME DEVELOPER: WATER; HYDROGEN PEROXIDE; CETEARYL ALCOHOL; TRIDECETH-2-CARBOXAMIDE MEA; CETEARETH-30; GLYCERIN; PENTASODIUM PENTETATE; SODIUM STANNATE; TETRASODIUM PYROPHOSPHATE. MULTI-MOISTURE CREME CONDITIONER: WATER; CETEARYL ALCOHOL; GLYCERIN; BEHENTRIMONIUM CHLORIDE; EUPHORBIA CERIFERA (CANDELILLA) WAX; AMODIMETHICONE; CETYL ESTERS; ISOPROPYL ALCOHOL; FRAGRANCE; METHYLPARABEN; TRIDECETH-12; PRUNUS ARMENIACA (APRICOT) KERNEL OIL; CHLORHEXIDINE DIHYDROCHLORIDE; CETRIMONIUM CHLORIDE.

Directions from packaging: Follow the enclosed instructions.

Warnings from packaging: Important: haircolor products can cause an allergic reaction which, in certain rare cases, can be serious. Therefore, before you use this product it is necessary to follow these precautions: do not use: if you have already had a reaction to a haircolor or hair lightening product. If you have a sensitive, itchy or damaged scalp. Perform an allergy test with a portion of this product 48 hours before full application (see the instruction sheet). Avoid contact with eyes and skin (other than areas of application). If product gets into eyes, rinse with lukewarm water immediately. Wear gloves provided in kit. Thoroughly rinse hair after application. Do not use for anything other than coloring your hair. Do not use on relaxed hair or just after bleaching your hair. Do not use over compound henna or progressive color. Do not inhale or ingest. Keep product out of the reach of children. This product contains ingredients which may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dyeing the eyelashes or eyebrows; to do so may cause blindness. This product contains persulfates and other ingredients which may cause serious irritant, respiratory and/or allergic reactions. Prepare and use only in a well-ventilated area. Enclosed insert contains important health and safety information. Follow the instructions. View All Products In Loreal Hair Color Category

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-30	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ETHANOLAMINE	5	66%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
POTASSIUM PERSULFATE	5	66%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
SODIUM PERSULFATE	5	69%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
M-AMINOPHENOL	6	65%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards
P-METHYLAMINOPHENOL SULFATE	5	60%	Cancer, Allergies/immunotoxicity, Occupational hazards
CHLORHEXIDINE DIHYDROCHLORIDE	4	73%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
4-AMINO-2-HYDROXYTOLUENE	5	67%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
OLETH-30	3	87%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TITANIUM DIOXIDE (NON-NANO)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
6-HYDROXYINDOLE	3	67%	Cancer, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
UREA	4	67%	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM METASILICATE	4	64%	Developmental/reproductive toxicity, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LAURETH-12	3	100%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CYAMOPSIS TETRAGONOLOBA (GUAR) GUM	1	79%	none identified
EDTA	3	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
AMMONIUM CHLORIDE	3	77%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
2-METHYL-5-HYDROXYETHYLAMINOPHENOL	3	73%	Cancer, Allergies/immunotoxicity
CETRIMONIUM CHLORIDE	3	71%	Allergies/immunotoxicity
SODIUM SILICATE	3	70%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
POLYQUATERNIUM-6	2	87%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
2-METHYLRESORCINOL	2	84%	Allergies/immunotoxicity
OLEIC ACID	1	82%	Irritation (skin, eyes, or lungs)
TETRASODIUM PYROPHOSPHATE	2	82%	Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
AMMONIUM HYDROXIDE	2	81%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DIOCTYL SODIUM SULFOSUCCINATE DIETHYLHEXYL SODIUM SULFOSUCCINATE	2	81%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
KAOLIN	1	79%	Occupational hazards
MAGNESIUM PEROXIDE	0	76%	none identified
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
SODIUM BENZOATE	2	69%	Organ system toxicity (non-reproductive)
BEHENTRIMONIUM CHLORIDE	0	94%	none identified
SODIUM CARBOXYMETHYL STARCH	0	94%	none identified
CETEARYL ALCOHOL	0	93%	none identified
ASCORBIC ACID (VITAMIN C)	1	91%	none identified
VP/ VA COPOLYMER	1	89%	none identified
DECETH-5	1	88%	Irritation (skin, eyes, or lungs)
SODIUM STANNATE	1	88%	Occupational hazards
TRIDECETH-12	1	88%	Organ system toxicity (non-reproductive)
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
MAGNESIUM STEARATE	1	83%	Occupational hazards
PENTASODIUM PENTETATE	0	74%	none identified
ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER	0	100%	none identified
DECETH-3	0	100%	none identified
HEXADIMETHRINE CHLORIDE	0	100%	none identified
POLYDECENE	0	100%	none identified
TRIDECETH-2 CARBOXAMIDE MEA	0	100%	none identified
AMMONIUM THIOLACTATE	0	100%	none identified
AMODIMETHICONE	0	99%	none identified
POLYQUATERNIUM-24	0	94%	none identified
PRUNUS ARMENIACA (APRICOT) KERNEL OIL	0	94%	none identified
EUPHORBIA CERIFERA (CANDELILLA) WAX	0	93%	none identified
CETYL ESTERS	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		CYAMOPSIS TETRAGONOLOBA (GUAR) GUM
One or more in vitro tests non-mammalian cells show positive mutation results		AMMONIUM HYDROXIDE
One or more in vitro tests on mammalian cells show positive mutation results		UREA, TITANIUM DIOXIDE (NON-NANO), SODIUM BENZOATE, OLEIC ACID, METHYLPARABEN, GLYCERIN, ETHANOLAMINE, EDTA, CETRIMONIUM CHLORIDE, ASCORBIC ACID (VITAMIN C), AMMONIUM CHLORIDE
Cancer - limited evidence		P-METHYLAMINOPHENOL SULFATE, M-AMINOPHENOL, 6-HYDROXYINDOLE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL, HYDROGEN PEROXIDE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		UREA, SODIUM BENZOATE, M-AMINOPHENOL, KAOLIN, ETHANOLAMINE, EDTA, DIOCTYL SODIUM SULFOSUCCINATE
One or more animal studies show reproductive effects at moderate doses		P-AMINOPHENOL, GLYCERIN
One or more animal studies show reproductive effects at low doses		SODIUM METASILICATE
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		SODIUM SILICATE, SODIUM PERSULFATE, SODIUM METASILICATE, SODIUM BENZOATE, POTASSIUM PERSULFATE, CHLORHEXIDINE DIHYDROCHLORIDE, ETHANOLAMINE, P-PHENYLENEDIAMINE, RESORCINOL, CETEARETH-30, CETRIMONIUM CHLORIDE, P-METHYLAMINOPHENOL SULFATE, P-AMINOPHENOL, M-AMINOPHENOL, 6-HYDROXYINDOLE, 4-AMINO-2-HYDROXYTOLUENE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-AMINOPHENOL, SODIUM PERSULFATE, POTASSIUM PERSULFATE, P-PHENYLENEDIAMINE
Determined safe for use in cosmetics, subject to concentration or use limitations - any		2-METHYL-5-HYDROXYETHYLAMINOPHENOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		M-AMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		P-PHENYLENEDIAMINE, UREA, CHLORHEXIDINE DIHYDROCHLORIDE, CHLORHEXIDINE DIHYDROCHLORIDE, RESORCINOL
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		4-AMINO-2-HYDROXYTOLUENE, GLYCERIN
One or more animal studies show brain and nervous system effects at moderate doses		POLYQUATERNIUM-6, RESORCINOL, UREA, SODIUM BENZOATE, P-AMINOPHENOL, OLEIC ACID, METHYLPARABEN, M-AMINOPHENOL, ETHANOLAMINE, KAOLIN, DIOCTYL SODIUM SULFOSUCCINATE, EDTA
One or more animal studies show brain and nervous system effects at low doses		TETRASODIUM PYROPHOSPHATE
One or more animal studies show brain and nervous system effects at moderate doses		AMMONIUM CHLORIDE, CETEARETH-30
One or more animal studies show brain and nervous system effects at very low doses		HYDROGEN PEROXIDE
Moderate evidence of human neurotoxicity		FRAGRANCE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		P-PHENYLENEDIAMINE, GLYCERIN, HYDROGEN PEROXIDE, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM, AMMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE
Human any disruptor - strong evidence		RESORCINOL, METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human immune system toxicant - moderate evidence		CHLORHEXIDINE DIHYDROCHLORIDE
Limited evidence of immune system toxicity	products for use on skin	6-HYDROXYINDOLE
Human skin toxicant - strong evidence		SODIUM SILICATE, SODIUM PERSULFATE, SODIUM METASILICATE, POTASSIUM PERSULFATE, METHYLPARABEN, M-AMINOPHENOL, ETHANOLAMINE, CETRIMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYLRESORCINOL, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL
Known human immune system toxicant		RESORCINOL, P-METHYLAMINOPHENOL SULFATE, P-AMINOPHENOL, FRAGRANCE, P-PHENYLENEDIAMINE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TITANIUM DIOXIDE (NON-NANO), SODIUM SILICATE, ISOPROPYL ALCOHOL, POLYQUATERNIUM-6, EDTA, AMMONIUM HYDROXIDE, AMMONIUM CHLORIDE
Not suspected to be persistent		TRIDECETH-12

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		SODIUM SILICATE
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		VP/ VA COPOLYMER, TRIDECETH-12, POLYQUATERNIUM-6
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-30
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		MAGNESIUM STEARATE, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		SODIUM METASILICATE, OLETH-30, POTASSIUM PERSULFATE, OLEIC ACID, CETRIMONIUM CHLORIDE, 4-AMINO-2-HYDROXYTOLUENE, 2-METHYLRESORCINOL, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, UREA
Limited evidence of sense organ toxicity		ISOPROPYL ALCOHOL
One or more animal studies show metabolic effects at low doses		TETRASODIUM PYROPHOSPHATE, SODIUM PERSULFATE, SODIUM BENZOATE, RESORCINOL, EDTA, DIOCTYL SODIUM SULFOSUCCINATE, AMMONIUM HYDROXIDE
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, HYDROGEN PEROXIDE, TITANIUM DIOXIDE (NON-NANO), AMMONIUM CHLORIDE
Possible human immune system toxicant		P-AMINOPHENOL, ETHANOLAMINE
Known human any toxicant		METHYLPARABEN, P-PHENYLENEDIAMINE
Possible human immune system toxicant		CHLORHEXIDINE DIHYDROCHLORIDE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		POTASSIUM PERSULFATE, SODIUM METASILICATE, HYDROGEN PEROXIDE, ISOPROPYL ALCOHOL, ETHANOLAMINE, AMMONIUM HYDROXIDE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		TRIDECETH-12, POLYQUATERNIUM-6, AMMONIUM CHLORIDE
Not suspected to be an environmental toxin		TITANIUM DIOXIDE (NON-NANO), SODIUM SILICATE, ISOPROPYL ALCOHOL, EDTA
Wildlife and environmental toxicity		RESORCINOL, P-PHENYLENEDIAMINE, P-METHYLAMINOPHENOL SULFATE, P-AMINOPHENOL, M-AMINOPHENOL, AMMONIUM HYDROXIDE, 6-HYDROXYINDOLE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SODIUM BENZOATE, P-METHYLAMINOPHENOL SULFATE, 4-AMINO-2-HYDROXYTOLUENE
One or more animal studies show skin irritation at moderate doses		TRIDECETH-12, TITANIUM DIOXIDE (NON-NANO), P-AMINOPHENOL, M-AMINOPHENOL
One or more animal studies show skin irritation at low doses		OLETH-30
One or more animal studies show skin irritation at moderate doses		GLYCERIN
One or more animal studies show skin irritation at low doses		UREA, OLEIC ACID, METHYLPARABEN, DIOCTYL SODIUM SULFOSUCCINATE, DECETH-5, CETEARETH-30
Human skin irritant - moderate evidence		ETHANOLAMINE, HYDROGEN PEROXIDE, CHLORHEXIDINE DIHYDROCHLORIDE, AMMONIUM HYDROXIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	SODIUM SILICATE
Classified as irritant		SODIUM METASILICATE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	OLEYL ALCOHOL
Classified as irritant		RESORCINOL, POTASSIUM PERSULFATE, P-PHENYLENEDIAMINE, ISOPROPYL ALCOHOL, EDTA, AMMONIUM CHLORIDE, 6-HYDROXYINDOLE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		CETYL ESTERS, OLETH-30, MAGNESIUM STEARATE, AMODIMETHICONE, SODIUM METASILICATE, ASCORBIC ACID (VITAMIN C), OLETH-30
Insufficient data to determine safety		4-AMINO-2-HYDROXYTOLUENE, M-AMINOPHENOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE
Safety assessment was based on related chemical		PENTASODIUM PENTETATE
Missing safety data noted by cosmetic industry review		P-PHENYLENEDIAMINE, PENTASODIUM PENTETATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		OLETH-30
Missing safety data noted by cosmetic industry review		P-AMINOPHENOL, M-AMINOPHENOL
Considered safe based on assumption of low absorption		4-AMINO-2-HYDROXYTOLUENE
Missing safety data noted by cosmetic industry review		4-AMINO-2-HYDROXYTOLUENE
Considered safe based on assumption of low absorption		SODIUM SILICATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		UREA
Considered safe based on assumption of low absorption		SODIUM METASILICATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		SODIUM METASILICATE, SODIUM SILICATE, RESORCINOL, P-PHENYLENEDIAMINE, PENTASODIUM PENTETATE, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, OLEYL ALCOHOL, OLEIC ACID, METHYLPARABEN, EDTA, MAGNESIUM STEARATE, M-AMINOPHENOL, DIOCTYL SODIUM SULFOSUCCINATE, CETYL ESTERS, CETEARYL ALCOHOL, EUPHORBIA CERIFERA (CANDELILLA) WAX, AMODIMETHICONE, ASCORBIC ACID (VITAMIN C)
Not assessed for safety in cosmetics by industry panel		TRIDECETH-12
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		2-METHYLRESORCINOL, 4-AMINO-2-HYDROXYTOLUENE
Not assessed for safety in cosmetics by industry panel		AMMONIUM THIOLACTATE, VP/ VA COPOLYMER, TRIDECETH-2 CARBOXAMIDE MEA, TITANIUM DIOXIDE (NON-NANO), TETRASODIUM PYROPHOSPHATE, SODIUM STANNATE, SODIUM CARBOXYMETHYL STARCH, PRUNUS ARMENIACA (APRICOT) KERNEL OIL, POLYQUATERNIUM-6, POLYQUATERNIUM-24, POLYDECENE, MAGNESIUM PEROXIDE, LAURETH-12, ISOPROPYL ALCOHOL, HYDROGEN PEROXIDE, HEXADIMETHRINE CHLORIDE, GLYCERIN, FRAGRANCE, DECETH-5, DECETH-3, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM, BEHENTRIMONIUM CHLORIDE, AMMONIUM HYDROXIDE, AMMONIUM CHLORIDE, ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER, 6-HYDROXYINDOLE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		SODIUM STANNATE
Allowed workplace exposures restricted to moderate doses		GLYCERIN, MAGNESIUM STEARATE, TETRASODIUM PYROPHOSPHATE
Allowed workplace exposures restricted to high doses		ISOPROPYL ALCOHOL
Allowed workplace exposures restricted to low doses		M-AMINOPHENOL, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE
Allowed workplace exposures restricted to very low doses		POTASSIUM PERSULFATE, SODIUM PERSULFATE
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), 6-HYDROXYINDOLE, AMMONIUM CHLORIDE
Allowed workplace exposures restricted to low doses		KAOLIN,
Allowed workplace exposures restricted to low doses		RESORCINOL, ETHANOLAMINE, HYDROGEN PEROXIDE
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		SODIUM BENZOATE
Interferes with gene expresion		METHYLPARABEN
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		DIOCTYL SODIUM SULFOSUCCINATE, GLYCERIN, HYDROGEN PEROXIDE