Sekkisei Emulsion (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

SEKKISEI EMULSION (2006 FORMULATION)

last updated: 05/01/06 brand: Sekkisei by KOSE America

SCORE

high hazard (out of 10)

84%

data gap

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100% of facial moisturizer/treatments have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: WATER, ALCOHOL, BUTYLENE GLYCOL, GLYCERIN, DIPROPYLENE GLYCOL, ASCORBYL GLUCOSIDE, PROPYLENE GLYCOL DICAPRATE, DIMETHICONE, CETYL ALCOHOL, DIPENTAERYTHRITYL HEXAHYDROXYSTEARATE/STEARATE/ROSINATE, SQUALANE, ANGELICA ACUTILOBA ROOT EXTRACT, COIX LACRYMA JOBI (JOB'S TEARS) SEED EXTRACT, GENTIANA LUTEA EXTRACT, INULA BRITANNICA FLOWER EXTRACT, MELOTHRIA HETEROPHYLLA EXTRACT, PAEONIA ALBIFLORA ROOT EXTRACT, POLYPHOSPHORYLCHOLINE GLYCOL ACRYLATE, TOCOPHERYL ACETATE, TRITICUM VULGARE (WHEAT) GERM OIL, C13-16 ISOPARAFFIN, CELLULOSE GUM, CITRIC ACID, DISODIUM EDTA, DISODIUM PHOSPHATE, ETHYLHEXYL METHOXYCINNAMATE, HYDROGENATED LECITHIN, HYDROGENATED RAPESEED GLYCERIDE, LAURETH 7, PEG-8, POLYACRYLAMIDE, PLYSORBATE 80, SODIUM HYDROXIDE, SODIUM METHYL STEAROYL TAURATE, SORBITAN STEARATE, ETHYLPARABEN, METHYLPARABEN, PROPYLPARABEN, FRAGRANCE (PARFUM)

Directions from packaging: + After toner, gently massage 1-2 pumps into skin. + Wipe the pump clean after use and place the cap back on firmly.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient)	8	65%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
PEG-8	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ETHANOL ALCOHOL	5	74%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
LAURETH-7	3	100%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DIMETHICONE	2	74%	Violations, restrictions & warnings
CITRIC ACID	3	72%	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
POLYACRYLAMIDE	3	71%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (ACRYLAMIDE)
POLYSORBATE-80 PLYSORBATE 80	2	80%	Developmental/reproductive toxicity
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
HYDROGENATED LECITHIN	2	74%	Enhanced skin absorption, Contamination concerns (NITROSAMINES)
SQUALANE	1	93%	Irritation (skin, eyes, or lungs)
SORBITAN STEARATE	1	92%	none identified
TRITICUM VULGARE (WHEAT) GERM OIL	1	90%	none identified
C13-16 ISOPARAFFIN	1	89%	Persistence and bioaccumulation
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DISODIUM PHOSPHATE	1	86%	none identified
DIPROPYLENE GLYCOL	1	84%	Irritation (skin, eyes, or lungs)
CELLULOSE GUM	1	80%	none identified
BUTYLENE GLYCOL	1	79%	Irritation (skin, eyes, or lungs)
ASCORBYL GLUCOSIDE	0	100%	none identified
COIX LACRYMA-JOBI (JOB'S TEARS) SEED EXTRACT	0	100%	none identified
DIPENTAERYTHRITYL HEXAHYDROXYSTEARATE/ STEARATE/ ROSINATE	0	100%	none identified
GENTIANA LUTEA (YELLOW GENTIAN) ROOT EXTRACT GENTIANA LUTEA EXTRACT	0	100%	none identified
HYDROGENATED RAPESEED GLYCERIDE	0	100%	none identified
INULA BRITANNICA (BRITISH YELLOWHEAD) FLOWER EXTRACT INULA BRITANNICA FLOWER EXTRACT	0	100%	none identified
MELOTHRIA HETEROPHYLLA EXTRACT	0	100%	none identified
POLYPHOSPHORYLCHOLINE GLYCOL ACRYLATE	0	100%	none identified
SODIUM METHYL STEAROYL TAURATE	0	100%	none identified
ANGELICA ACUTILOBA	0	100%	none identified
PAEONIA ALBIFLORA ROOT EXTRACT	0	100%	none identified
PROPYLENE GLYCOL DICAPRATE	0	90%	Enhanced skin absorption
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		CELLULOSE GUM
One or more in vitro tests non-mammalian cells show positive mutation results		TRITICUM VULGARE (WHEAT) GERM OIL
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHERYL ACETATE, SODIUM HYDROXIDE, PROPYLPARABEN, PROPYLENE GLYCOL, POLYSORBATE-80, METHYLPARABEN, GLYCERIN, ETHYLPARABEN, DISODIUM EDTA
Cancer - limited evidence		ETHANOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		BUTYLENE GLYCOL, DISODIUM EDTA, ETHYLPARABEN
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at moderate doses		CELLULOSE GUM, GLYCERIN
One or more animal studies show reproductive effects at very low doses		POLYSORBATE-80
Limited evidence of reproductive toxicity		ETHANOL

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PROPYLENE GLYCOL, POLYACRYLAMIDE, PEG-8
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		HYDROGENATED LECITHIN
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		ETHANOL
One or more animal studies show brain and nervous system effects at high doses		PROPYLENE GLYCOL, POLYSORBATE-80, BUTYLENE GLYCOL, DIPROPYLENE GLYCOL, GLYCERIN, POLYACRYLAMIDE
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA
One or more animal studies show brain and nervous system effects at moderate doses		DISODIUM PHOSPHATE, METHYLPARABEN
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		GLYCERIN, DISODIUM EDTA, BUTYLENE GLYCOL
Human any disruptor - strong evidence		PROPYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), ETHYLPARABEN, METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		PROPYLPARABEN, TOCOPHERYL ACETATE, METHYLPARABEN, ETHYLPARABEN
Known human immune system toxicant		FRAGRANCE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		SODIUM HYDROXIDE
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Not suspected to be persistent		CETYL ALCOHOL
Not suspected to be bioaccumulative		ETHANOL, POLYACRYLAMIDE
Persistent, bioaccumulative in wildlife		C13-16 ISOPARAFFIN

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		CELLULOSE GUM
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	TRITICUM VULGARE (WHEAT) GERM OIL, PROPYLENE GLYCOL, DIPROPYLENE GLYCOL, POLYSORBATE-80, CETYL ALCOHOL
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		POLYACRYLAMIDE,
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	BUTYLENE GLYCOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		DISODIUM PHOSPHATE, TOCOPHERYL ACETATE
Limited evidence of sense organ toxicity		PEG-8, PROPYLPARABEN, ETHYLPARABEN
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ETHANOL, CITRIC ACID
One or more animal studies show metabolic effects at very low doses		SODIUM HYDROXIDE, GLYCERIN
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		SODIUM HYDROXIDE, ETHANOL

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		TOCOPHERYL ACETATE, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM HYDROXIDE, SORBITAN STEARATE, POLYSORBATE-80, POLYACRYLAMIDE, PEG-8, METHYLPARABEN, GLYCERIN, GENTIANA LUTEA (YELLOW GENTIAN) ROOT EXTRACT, ETHANOL, DISODIUM PHOSPHATE, DISODIUM EDTA, DIMETHICONE, CITRIC ACID, CETYL ALCOHOL, CELLULOSE GUM, BUTYLENE GLYCOL
Used in food or as an additive with limited or no toxicity information available		ETHANOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		POLYACRYLAMIDE, CETYL ALCOHOL
Not suspected to be an environmental toxin		SODIUM HYDROXIDE, ETHANOL
Wildlife and environmental toxicity		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		TRITICUM VULGARE (WHEAT) GERM OIL, SORBITAN STEARATE, GLYCERIN, DISODIUM PHOSPHATE
One or more animal studies show skin irritation at low doses		SQUALANE
One or more animal studies show skin irritation at moderate doses		CITRIC ACID
One or more animal studies show skin irritation at low doses		METHYLPARABEN, ETHANOL
One or more animal studies show skin irritation at very low doses		SODIUM HYDROXIDE, CETYL ALCOHOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	DIPROPYLENE GLYCOL, BUTYLENE GLYCOL
Classified as skin irritant		PROPYLENE GLYCOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PROPYLENE GLYCOL DICAPRATE, PROPYLENE GLYCOL
Considered safe based on assumption of low absorption		POLYACRYLAMIDE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		METHYLPARABEN, TRITICUM VULGARE (WHEAT) GERM OIL, ETHYLPARABEN, PROPYLENE GLYCOL DICAPRATE, TOCOPHERYL ACETATE, SORBITAN STEARATE, PROPYLPARABEN, POLYSORBATE-80, DISODIUM EDTA, DIPROPYLENE GLYCOL, DIMETHICONE, CELLULOSE GUM, CETYL ALCOHOL, BUTYLENE GLYCOL
Not assessed for safety in cosmetics by industry panel		PAEONIA ALBIFLORA ROOT EXTRACT, ANGELICA ACUTILOBA, SQUALANE, SODIUM METHYL STEAROYL TAURATE, SODIUM HYDROXIDE, POLYPHOSPHORYLCHOLINE GLYCOL ACRYLATE, MELOTHRIA HETEROPHYLLA EXTRACT, LAURETH-7, INULA BRITANNICA (BRITISH YELLOWHEAD) FLOWER EXTRACT, HYDROGENATED RAPESEED GLYCERIDE, GLYCERIN, GENTIANA LUTEA (YELLOW GENTIAN) ROOT EXTRACT, FRAGRANCE, ETHANOL, DISODIUM PHOSPHATE, DIPENTAERYTHRITYL HEXAHYDROXYSTEARATE/ STEARATE/ ROSINATE, COIX LACRYMA-JOBI (JOB'S TEARS) SEED EXTRACT, CITRIC ACID, C13-16 ISOPARAFFIN, ASCORBYL GLUCOSIDE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to high doses		ETHANOL
No workplace limits set		SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CELLULOSE GUM, CITRIC ACID, ETHANOL, GLYCERIN, POLYACRYLAMIDE, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		METHYLPARABEN