

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Sodium monofluorophosphate; glycerin; water; hydrated silica; calcium carbonate; xylitol; natural flavors; sodium lauryl sulfate; Chondrus crispus (carrageenan); Glycyrrhiza uralensis (licorice) root extract;
Directions from packaging: brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. use only a pea sized amount and supervise child’s brushing and rinsing (to minimize swallowing). children under 2 years: ask a dentist or physician.
Warnings from packaging: Keep out of the reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or dial (412) 390-3381 right away (Poison Control Center).
| score | data gap | concerns | |
| SODIUM MONOFLUOROPHOSPHATE (Active Ingredient) | 6 | 69% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| CARRAGEENAN | 2 | 75% | Organ system toxicity (non-reproductive), Contamination concerns (DEGRADED CARRAGEENAN), Biochemical or cellular level changes |
| MENTHA PIPERITA (PEPPERMINT) OIL | 3 | 73% | Enhanced skin absorption, Contamination concerns (LIMONENE, MENTHOL, MENTHONE) |
| SODIUM LAURYL SULFATE | 3 | 68% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| HYDRATED SILICA | 2 | 79% | Persistence and bioaccumulation |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| XYLITOL | 1 | 88% | none identified |
| CALCIUM CARBONATE | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT | 1 | 85% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, MENTHA PIPERITA (PEPPERMINT) OIL | |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM MONOFLUOROPHOSPHATE, SODIUM LAURYL SULFATE, GLYCERIN | |
| Not likely to be carcinogenic in humans | CARRAGEENAN | |
| Cancer - not classifiable/not likely to be human carcinogen | HYDRATED SILICA |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN | |
| Human nervous system toxicant - moderate evidence | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAURYL SULFATE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SODIUM MONOFLUOROPHOSPHATE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | MENTHA PIPERITA (PEPPERMINT) OIL |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM LAURYL SULFATE, GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT | |
| One or more animal studies show brain and nervous system effects at high doses | GLYCERIN, XYLITOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | MENTHA PIPERITA (PEPPERMINT) OIL, CARRAGEENAN | |
| Strong evidence of human neurotoxicity | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | SODIUM LAURYL SULFATE, GLYCERIN | |
| One or more animal studies show endocrine disruption at moderate doses | GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be persistent | SODIUM LAURYL SULFATE | |
| Persistent, bioaccumulative in wildlife and humans | HYDRATED SILICA |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | XYLITOL, MENTHA PIPERITA (PEPPERMINT) OIL | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | CALCIUM CARBONATE |
| One or more animal studies show broad systemic effects at low doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient) | GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT | |
| One or more animal studies show broad systemic effects at very low doses | SODIUM MONOFLUOROPHOSPHATE, CARRAGEENAN |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | SODIUM LAURYL SULFATE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at low doses | CALCIUM CARBONATE | |
| One or more animal studies show skin irritation at moderate doses | GLYCERIN | |
| One or more animal studies show skin irritation at very low doses | SODIUM LAURYL SULFATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not assessed for safety in cosmetics by industry panel | HYDRATED SILICA, GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT, XYLITOL, SODIUM MONOFLUOROPHOSPHATE, GLYCERIN, CARRAGEENAN, CALCIUM CARBONATE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, CALCIUM CARBONATE | |
| Allowed workplace exposures restricted to low doses | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | XYLITOL, GLYCERIN | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | SODIUM LAURYL SULFATE | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | CARRAGEENAN |
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