B. Kamins MALE Bio-Maple Anti-Aging Soothing Eye Gel (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

B. KAMINS MALE BIO-MAPLE ANTI-AGING SOOTHING EYE GEL (2006 FORMULATION)

last updated: 05/01/06 brand: B. Kamins by Kamins Dermatologics

SCORE

moderate hazard (out of 10)

81%

data gap

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44% of anti-agings have lower concerns
45% of around-eye creams have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: WATER (AQUA), CYCLOMETHICONE, SODIUM HYALURONATE, HYDROLYZED GLYCOSAMINOGLYCANS, PEG 8, SORBITAN STEARATE, SUCROSE COCOATE, GLYCERIN, SQUALANE, POLYACRYLAMIDE, C13 & 14 ISOPARAFFIN, LAURETH 7, ESCULIN, CUCUMIS SATIVUS FRUIT EXTRACT (CUCUMBER), BIO-MAPLE (ACER SACCHARUM, MAPLE ISOLATE), TOCOPHERYL ACETATE (VITAMIN E), RETINYL PALMITATE (VITAMIN A), ALOE BARBADENSIS LEAF JUICE POWDER, PHENOXYETHANOL, METHYLPARABEN, ETHYLPARABEN, BUTYLPARABEN, PROPYLPARABEN

Directions from packaging: After cleansing, apply morning and night to outer eye area. Reapply as needed.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
BUTYLPARABEN	6	79%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PEG-8	4	76%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
RETINYL PALMITATE	5	68%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
LAURETH-7	3	100%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
POLYACRYLAMIDE	3	71%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (ACRYLAMIDE)
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
C13-14 ISOPARAFFIN	1	93%	none identified
SQUALANE	1	93%	Irritation (skin, eyes, or lungs)
SORBITAN STEARATE	1	92%	none identified
ESCULIN	1	87%	Biochemical or cellular level changes
SODIUM HYALURONATE	1	83%	none identified
ALOE BARBADENSIS (ALOE VERA) LEAF JUICE POWDER ALOE BARBADENSIS LEAF JUICE POWDER	1	73%	none identified
ACER SACCHARUM (MAPLE) ISOLATE	0	100%	none identified
ACER SACCHARUM (SUGAR MAPLE) EXTRACT	0	100%	none identified
BIO-MAPLE COMPOUND	0	100%	none identified
CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT CUCUMIS SATIVUS FRUIT EXTRACT (CUCUMBER)	0	100%	none identified
HYDROLYZED GLYCOSAMINOGLYCANS	0	100%	none identified
SUCROSE COCOATE	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN, GLYCERIN, ETHYLPARABEN
Cancer - limited evidence		RETINYL PALMITATE
One or more in vitro tests on mammalian cells show positive mutation results		BUTYLPARABEN

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at moderate doses		SODIUM HYALURONATE
One or more animal studies show reproductive effects at high doses		ETHYLPARABEN
One or more animal studies show reproductive effects at moderate doses		GLYCERIN
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) LEAF JUICE POWDER
One or more animal studies show any effects at very low doses		BUTYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-8, POLYACRYLAMIDE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		PHENOXYETHANOL, RETINYL PALMITATE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ALOE BARBADENSIS (ALOE VERA) LEAF JUICE POWDER

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN, POLYACRYLAMIDE, RETINYL PALMITATE
One or more animal studies show brain and nervous system effects at moderate doses		PHENOXYETHANOL, SODIUM HYALURONATE, METHYLPARABEN

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		GLYCERIN
Human any disruptor - strong evidence		PROPYLPARABEN, METHYLPARABEN, ETHYLPARABEN, BUTYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN, ETHYLPARABEN, BUTYLPARABEN

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		POLYACRYLAMIDE
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	SODIUM HYALURONATE
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		POLYACRYLAMIDE,
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CYCLOMETHICONE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		TOCOPHERYL ACETATE, ESCULIN,
One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)		C13-14 ISOPARAFFIN
Limited evidence of skin toxicity		RETINYL PALMITATE, PROPYLPARABEN, PEG-8, ETHYLPARABEN, BUTYLPARABEN
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	PHENOXYETHANOL
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN
Known human any toxicant		METHYLPARABEN

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		POLYACRYLAMIDE
Wildlife and environmental toxicity		PROPYLPARABEN
Suspected to be an environmental toxin		CYCLOMETHICONE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		SORBITAN STEARATE, SODIUM HYALURONATE, GLYCERIN, CYCLOMETHICONE, BUTYLPARABEN
One or more animal studies show skin irritation at low doses		SQUALANE, METHYLPARABEN
Classified as irritant		PHENOXYETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Considered safe based on assumption of low absorption		POLYACRYLAMIDE
Missing safety data noted by cosmetic industry review		ALOE BARBADENSIS (ALOE VERA) LEAF JUICE POWDER
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHERYL ACETATE, SORBITAN STEARATE, RETINYL PALMITATE, PHENOXYETHANOL, PROPYLPARABEN, METHYLPARABEN, ETHYLPARABEN
Not assessed for safety in cosmetics by industry panel		CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT, ESCULIN, GLYCERIN, HYDROLYZED GLYCOSAMINOGLYCANS, LAURETH-7, SQUALANE, SUCROSE COCOATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BUTYLPARABEN, CYCLOMETHICONE
Not assessed for safety in cosmetics by industry panel		C13-14 ISOPARAFFIN, BIO-MAPLE COMPOUND, ACER SACCHARUM (SUGAR MAPLE) EXTRACT, ACER SACCHARUM (MAPLE) ISOLATE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		PHENOXYETHANOL
Allowed workplace exposures restricted to moderate doses		GLYCERIN

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Interferes with gene expresion		METHYLPARABEN, BUTYLPARABEN
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		POLYACRYLAMIDE, GLYCERIN, CYCLOMETHICONE
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		ESCULIN