Physician's Complex Dermal Relaxer || Skin Deep: Cosmetic Safety Reviews

PHYSICIAN'S COMPLEX DERMAL RELAXER

last updated: 05/01/06 brand: Physician's Complex by CosMed

SCORE

moderate hazard (out of 10)

79%

data gap

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57% of anti-agings have lower concerns
62% of facial moisturizer/treatments have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
New Signer: This company has recently signed the Compact for Safe Cosmetics and is working toward compliance.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Contamination concerns, Biochemical or cellular level changes

Ingredients from packaging: WATER, GLYCERYL STEARATE, SESAME OIL, CAPRYLIC/CAPRIC TRIGLYCERIDE, PEG-150 DISTEARATE, CETYL ALCOHOL, GYNOSTEMMA, BISMUTH OXY CHLORIDE, GAMMA AMINO BUTYRIC ACID, EUGENOL, ETHOXYDIGLYCOL, POLYSORBATE 60, BUTYLENE GLYCOL, XANTHAN GUM, METHYLPARABEN, PROPYLPARABEN, ETHYLPARABEN, FRAGRANCE.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
EUGENOL	7	56%	Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
PEG-150 DISTEARATE	4	73%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
GAMMA AMINOBUTYRIC ACID	3	80%	Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive)
ETHOXYDIGLYCOL	2	82%	Organ system toxicity (non-reproductive)
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	none identified
BISMUTH OXYCHLORIDE	1	89%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
POLYSORBATE-60	1	81%	none identified
BUTYLENE GLYCOL	1	79%	Irritation (skin, eyes, or lungs)
GYNOSTEMMA PENTAPHYLLUM	0	100%	none identified
SESAMUM INDICUM (SESAME) OIL	0	99%	none identified
XANTHAN GUM	0	94%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		POLYSORBATE-60
One or more in vitro tests non-mammalian cells show positive mutation results		ETHOXYDIGLYCOL
One or more in vitro tests on mammalian cells show positive mutation results		PROPYLPARABEN, METHYLPARABEN, ETHYLPARABEN
Not likely to be carcinogenic in humans		EUGENOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		POLYSORBATE-60, GAMMA AMINOBUTYRIC ACID, ETHYLPARABEN, ETHOXYDIGLYCOL, BUTYLENE GLYCOL
One or more animal studies show any effects at low doses		PROPYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-150 DISTEARATE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)		EUGENOL
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		ETHOXYDIGLYCOL, BUTYLENE GLYCOL
One or more animal studies show brain and nervous system effects at moderate doses		METHYLPARABEN
One or more animal studies show brain and nervous system effects at low doses		EUGENOL
One or more animal studies show brain and nervous system effects at very low doses		GAMMA AMINOBUTYRIC ACID
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more studies show endocrine system disruption at very low doses		GAMMA AMINOBUTYRIC ACID
One or more animal studies show endocrine system disruption at high doses		BUTYLENE GLYCOL
Human any disruptor - strong evidence		PROPYLPARABEN, METHYLPARABEN, ETHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human skin toxicant - strong evidence		METHYLPARABEN, PROPYLPARABEN, ETHYLPARABEN
Known human immune system toxicant		EUGENOL, FRAGRANCE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		BISMUTH OXYCHLORIDE
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CETYL ALCOHOL, BUTYLENE GLYCOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		POLYSORBATE-60, GLYCERYL MONOSTEARATE
Limited evidence of sense organ toxicity		PROPYLPARABEN, PEG-150 DISTEARATE, ETHYLPARABEN
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	ETHOXYDIGLYCOL
One or more animal studies show cardiovascular effects at low doses		EUGENOL
One or more animal studies show broad systemic effects at very low doses		GAMMA AMINOBUTYRIC ACID
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		CETYL ALCOHOL
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		ETHOXYDIGLYCOL
One or more animal studies show skin irritation at low doses		METHYLPARABEN
One or more animal studies show skin irritation at very low doses		EUGENOL, CETYL ALCOHOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PEG-150 DISTEARATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		SESAMUM INDICUM (SESAME) OIL, POLYSORBATE-60, PEG-150 DISTEARATE, PROPYLPARABEN, ETHYLPARABEN, GLYCERYL MONOSTEARATE, METHYLPARABEN
Not assessed for safety in cosmetics by industry panel		GYNOSTEMMA PENTAPHYLLUM, XANTHAN GUM
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BUTYLENE GLYCOL, CETYL ALCOHOL, ETHOXYDIGLYCOL
Not assessed for safety in cosmetics by industry panel		GAMMA AMINOBUTYRIC ACID, FRAGRANCE, EUGENOL, CAPRYLIC/ CAPRIC TRIGLYCERIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Interferes with gene expresion		METHYLPARABEN