B. Kamins Glycolic-8, Glycolic-8 (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

B. KAMINS GLYCOLIC-8, GLYCOLIC-8 (2006 FORMULATION)

last updated: 05/01/06 brand: B. Kamins by Kamins Dermatologics

SCORE

moderate hazard (out of 10)

70%

data gap

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35% of anti-agings have lower concerns
42% of facial moisturizer/treatments have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: WATER/EAU (AQUA), GLYCOLIC ACID 8%/ACIDE GLYCOLIQUE 8%, BIO-MAPLE COMPOUND (ACER SACCHARUM ISOLATE), LAURETH-4, PHENOXYETHANOL, BUTYPARABEN, ETHYLPARABEN, METHYLPARABEN. MAY CONTAIN SODIUM HYDROXIDE TO ADJUST PH.

Directions from packaging: Apply morning and night to cleansed skin using the applicator to target specific problem areas on the face and neck, avoiding eye area.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
BUTYLPARABEN BUTYPARABEN	6	79%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
GLYCOLIC ACID	4	70%	Violations, restrictions & warnings
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
LAURETH-4	3	96%	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
SODIUM HYDROXIDE	3	77%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ACER SACCHARUM (MAPLE) ISOLATE BIO-MAPLE COMPOUND (ACER SACCHARUM ISOLATE)	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL
One or more in vitro tests on mammalian cells show positive mutation results		SODIUM HYDROXIDE, METHYLPARABEN, ETHYLPARABEN, BUTYLPARABEN

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		ETHYLPARABEN, GLYCOLIC ACID
One or more animal studies show any effects at very low doses		BUTYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		GLYCOLIC ACID
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		GLYCOLIC ACID, PHENOXYETHANOL
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits		GLYCOLIC ACID

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at moderate doses		METHYLPARABEN, PHENOXYETHANOL, GLYCOLIC ACID
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		BUTYLPARABEN, METHYLPARABEN, ETHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
Human skin toxicant - strong evidence		ETHYLPARABEN, METHYLPARABEN, BUTYLPARABEN

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		PHENOXYETHANOL, GLYCOLIC ACID
Limited evidence of sense organ toxicity		ETHYLPARABEN, BUTYLPARABEN
One or more animal studies show metabolic effects at very low doses		SODIUM HYDROXIDE
Known human any toxicant		METHYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		BUTYLPARABEN
One or more animal studies show skin irritation at low doses		METHYLPARABEN
One or more animal studies show skin irritation at very low doses		SODIUM HYDROXIDE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	LAURETH-4
Classified as irritant		PHENOXYETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PHENOXYETHANOL
Safety assessment was based on related chemical		LAURETH-4
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		METHYLPARABEN, LAURETH-4, ETHYLPARABEN
Not assessed for safety in cosmetics by industry panel		SODIUM HYDROXIDE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BUTYLPARABEN
Not assessed for safety in cosmetics by industry panel		ACER SACCHARUM (MAPLE) ISOLATE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
No workplace limits set		SODIUM HYDROXIDE, GLYCOLIC ACID
Allowed workplace exposures restricted to low doses		PHENOXYETHANOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN