OBAGI-C RX SYSTEM C CLARIFYING SERUM (2006 FORMULATION)
last updated: 05/01/06 brand: OBAGI by OBAGI Medical Products
COMPANY POLICIES
Compact for Safe Cosmetics
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Animal Testing Policy |
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
Ingredients from packaging: EACH GRAM OF OBAGI-C RX SYSTEM C-CLARIFYING SERUM CONTAINS HYDROQUINON USP 40 MG/GM IN A BASE OF PROPYLENE GLYCOL, PROPYLENE CARBONATE, L-ASCORBATE ACID (VITAMIN C), PURIFIED WATER AND SODIUM LAURYL SULFATE
Directions from packaging: A thin application should be applied daily to the affected area.
user reviews & comments
| anonymous 595 | "Hydroquinon is not listed as an ingredient even though you list it from the manufacturers list. This would make it a very hazardous product - not a 1 ..." Thank you for your comment! We have corrected the formulation in the database. -- Skin Deep Admin |
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ingredients
| score | data gap | concerns | |
| HYDROQUINONE | 10 | 52% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| SODIUM LAURYL SULFATE | 3 | 68% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ASCORBIC ACID (VITAMIN C) L-ASCORBATE ACID (VITAMIN C) | 1 | 91% | none identified |
| PROPYLENE CARBONATE | 1 | 85% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| WATER (PURIFIED) | 0 | 0% | innocuous |
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM LAURYL SULFATE, PROPYLENE GLYCOL, ASCORBIC ACID (VITAMIN C) | |
| Limited evidence of carcinogenicity | HYDROQUINONE |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL | |
| One or more animal studies show reproductive effects at high doses | SODIUM LAURYL SULFATE | |
| Human nervous system toxicant - moderate evidence | HYDROQUINONE |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAURYL SULFATE, PROPYLENE GLYCOL | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Safe for brief discontinuous use followed by thorough rinsing | products that are intended to be left on the skin | HYDROQUINONE |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | HYDROQUINONE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - any | HYDROQUINONE, HYDROQUINONE |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Strong evidence of human neurotoxicity | HYDROQUINONE | |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show brain and nervous system effects at high doses | PROPYLENE GLYCOL |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | SODIUM LAURYL SULFATE, HYDROQUINONE |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Known human immune system toxicant | HYDROQUINONE |
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) | products for use around the eyes, mouth, or lips | PROPYLENE GLYCOL |
| One or more animal studies show sense organ effects at low doses | products for use around the eyes, mouth, or lips | PROPYLENE CARBONATE |
| One or more animal studies show broad systemic effects at low doses | SODIUM LAURYL SULFATE | |
| Known human respiratory toxicant | HYDROQUINONE |
Ecotoxicology*
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | SODIUM LAURYL SULFATE | |
| Wildlife and environmental toxicity | HYDROQUINONE |
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as irritant | PROPYLENE CARBONATE, PROPYLENE GLYCOL | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | SODIUM LAURYL SULFATE |
| One or more animal studies show skin irritation at very low doses | HYDROQUINONE |
Data gaps*
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | ASCORBIC ACID (VITAMIN C), PROPYLENE GLYCOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | ASCORBIC ACID (VITAMIN C), PROPYLENE CARBONATE |
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | HYDROQUINONE |
Biochemical or cellular level changes*
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | SODIUM LAURYL SULFATE | |
| One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood | PROPYLENE GLYCOL |
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