Earth Science Placentagen Eye & Throat Cream (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

EARTH SCIENCE PLACENTAGEN EYE & THROAT CREAM (2006 FORMULATION)

last updated: 05/01/06 brand: Earth Science by Earth Essentials, Inc.

SCORE

moderate hazard (out of 10)

83%

data gap

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28% of facial moisturizer/treatments have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: PURIFIED WATER, APRICOT OIL, KOLA NUT EXTRACT, ALOE VERA JUICE, GLYCERYL STEARATE, PEG-100 STEARATE, GLYCERIN (VEGETABLE), CETYL ALCOHOL, PLACENTAL EXTRACT, TOCOPHEROL, SOYA STEROL, HYALURONIC ACID, ASCORBIC ACID, GRAPEFRUIT SEED EXTRACT, SORBIC ACID, DIMETHICONE, RETINYL PALMITATE, LAVENDER EXTRACT, GARDENIA OIL, GRAPESKIN EXTRACT, ALLANTOIN.

Directions from packaging: Gently smooth a small amount into the skin massaging away from the eyes. Gently massage the throat area with a small amount using gentle upward strokes.

Warnings from packaging: Do not get into eyes.

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ingredients

	score	data gap	concerns
PEG-100 STEARATE	4	69%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PLACENTAL EXTRACT	5	75%	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (PROGESTERONE, ESTROGEN, ESTRONE)
RETINYL PALMITATE	5	68%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT	4	100%	Multiple, additive exposure sources, Contamination concerns (BENZETHONIUM CHLORIDE, METHYLPARABEN, TRICLOSAN)
SORBIC ACID	3	80%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DIMETHICONE	2	74%	Violations, restrictions & warnings
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
ASCORBIC ACID (VITAMIN C)	1	91%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ALOE BARBADENSIS (ALOE VERA) JUICE	1	73%	none identified
COLA ACUMINATA (KOLA) SEED EXTRACT KOLA NUT EXTRACT	0	100%	none identified
GLYCINE SOJA (SOYBEAN) STEROLS SOYA STEROL	0	100%	none identified
LAVANDULA ANGUSTIFOLIA (LAVENDER) EXTRACT	0	100%	none identified
VITIS VINIFERA (GRAPE) SKIN EXTRACT	0	100%	none identified
GARDENIA FLORIDA OIL GARDENIA OIL	0	100%	none identified
ALLANTOIN	0	94%	none identified
HYALURONIC ACID	0	94%	none identified
PRUNUS ARMENIACA (APRICOT) OIL	0	94%	none identified
WATER (PURIFIED)	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at moderate doses		PEG-100 STEARATE
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHEROL, SORBIC ACID, GLYCERIN, ASCORBIC ACID (VITAMIN C)
Cancer - limited evidence		RETINYL PALMITATE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		PEG-100 STEARATE
One or more animal studies show reproductive effects at moderate doses		GLYCERIN,
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) JUICE
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		RETINYL PALMITATE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ALOE BARBADENSIS (ALOE VERA) JUICE, PEG-100 STEARATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		PLACENTAL EXTRACT

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		RETINYL PALMITATE, GLYCERIN

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		GLYCERIN
One or more studies show weak endocrine disruption		PLACENTAL EXTRACT

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human skin toxicant - strong evidence		SORBIC ACID

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show cardiovascular effects at high doses (low dose studies may be unavailable for this ingredient)		CETYL ALCOHOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		GLYCERYL MONOSTEARATE
Limited evidence of skin toxicity		RETINYL PALMITATE, PEG-100 STEARATE, SORBIC ACID
Potential risk of infectious disease - any		PLACENTAL EXTRACT
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PEG-100 STEARATE, VITIS VINIFERA (GRAPE) SKIN EXTRACT, TOCOPHEROL, SORBIC ACID, RETINYL PALMITATE, PRUNUS ARMENIACA (APRICOT) OIL, GLYCERYL MONOSTEARATE, GLYCERIN, DIMETHICONE, CETYL ALCOHOL, ASCORBIC ACID (VITAMIN C)
Used in food or as an additive with limited or no toxicity information available		CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		CETYL ALCOHOL

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		GLYCERIN
One or more animal studies show skin irritation at very low doses		PEG-100 STEARATE, SORBIC ACID, CETYL ALCOHOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		ASCORBIC ACID (VITAMIN C), PEG-100 STEARATE
Missing safety data noted by cosmetic industry review		ALOE BARBADENSIS (ALOE VERA) JUICE
Insufficient data to determine safety		PLACENTAL EXTRACT
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PEG-100 STEARATE, TOCOPHEROL, RETINYL PALMITATE, SORBIC ACID, GLYCERYL MONOSTEARATE, DIMETHICONE
Not assessed for safety in cosmetics by industry panel		ALLANTOIN, CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT, COLA ACUMINATA (KOLA) SEED EXTRACT
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		CETYL ALCOHOL, ASCORBIC ACID (VITAMIN C)
Not assessed for safety in cosmetics by industry panel		GARDENIA FLORIDA OIL, VITIS VINIFERA (GRAPE) SKIN EXTRACT, PRUNUS ARMENIACA (APRICOT) OIL, GLYCERIN, GLYCINE SOJA (SOYBEAN) STEROLS, LAVANDULA ANGUSTIFOLIA (LAVENDER) EXTRACT

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		GLYCERIN

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		GLYCERIN
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE