

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards |
Ingredients from packaging: ACTIVE INGREDIENTS CALAMINE (3.0%), PRAMOXINE HCI (1.0%), CAMPHOR (0.47%) INGREDIENTS PETROLATUM, ISOPROPYL PALMITATE, CETYL ALCOHOL, DIMETHICONE, SODIUM CHLORIDE, OAT FLOUR AVENA SATIVA
Directions from packaging: Adults and Children 2 years and older: Apply no more than 4 times daily. Children under 2 years of age: Do not use, consult a physician.
Warnings from packaging: + For external use only. + Avoid contact with eyes. + If condition does not improve or recurs within 7 days, discontinue use and consult a physician. + Keep this and all drugs out of the reach of children. + In case of accidental ingestion, seek professional assistance or contact a Poison Control Center immediately. + Store at 59-86 degrees F.
| score | data gap | concerns | |
| CAMPHOR (Active Ingredient) | 4 | 69% | Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| PETROLATUM | 2 | 94% | Organ system toxicity (non-reproductive), Contamination concerns (PAHS) |
| CALAMINE (Active Ingredient) | 0 | 94% | none identified |
| CETYL ALCOHOL | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ISOPROPYL PALMITATE | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| PRAMOXINE HCL PRAMOXINE HCI (Active Ingredient) | 1 | 87% | Neurotoxicity, Organ system toxicity (non-reproductive) |
| AVENA SATIVA (OAT) KERNEL FLOUR OAT FLOUR AVENA SATIVA | 0 | 94% | none identified |
| SODIUM CHLORIDE | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM CHLORIDE, CAMPHOR |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | CAMPHOR | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at low doses | CAMPHOR, PRAMOXINE HCL |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as expected to be toxic or harmful | PETROLATUM | |
| One or more animal studies show cardiovascular effects at high doses (low dose studies may be unavailable for this ingredient) | CETYL ALCOHOL | |
| One or more animal studies show broad systemic effects at low doses | PRAMOXINE HCL, CAMPHOR, ISOPROPYL PALMITATE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | CETYL ALCOHOL | |
| Not suspected to be an environmental toxin | PETROLATUM |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | SODIUM CHLORIDE | |
| One or more animal studies show skin irritation at low doses | ISOPROPYL PALMITATE | |
| One or more animal studies show skin irritation at very low doses | CETYL ALCOHOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | ISOPROPYL PALMITATE, CETYL ALCOHOL | |
| Not assessed for safety in cosmetics by industry panel | AVENA SATIVA (OAT) KERNEL FLOUR, CALAMINE, CAMPHOR, PETROLATUM, PRAMOXINE HCL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DIMETHICONE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | CAMPHOR |
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