Pevonia Botanica Refining Marine D.N.A. Concentrate || Skin Deep: Cosmetic Safety Reviews

PEVONIA BOTANICA REFINING MARINE D.N.A. CONCENTRATE

last updated: 05/01/06 brand: Pevonia Botanica by Pevonia Botanica

SCORE

moderate hazard (out of 10)

68%

data gap

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33% of facial moisturizer/treatments have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-compliant: This company has signed the Compact for Safe Cosmetics but is not in compliance because of their use of one or more ingredients prohibited or restricted under the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: WATER, DNA, GLYCERIN, CARBOMER, POLYSORBATE 20, SODIUM CHLORIDE, PECTIN, SODIUM HYDROXIDE, GARDENIA FLOWER EXTRACT, METHYLPARABEN, PROPYLPARABEN

Directions from packaging: Apply 5 to 7 drops on clean skin all over face and neck. Massage gently. Recommended for dehydrated skin with dilated pores and uneven texture. Apply in the evening. Best results when used before the DNA Cream.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PECTIN	2	88%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
SODIUM HYDROXIDE	3	77%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
DNA	1	97%	none identified
POLYSORBATE-20	1	84%	none identified
GARDENIA FLORIDA EXTRACT GARDENIA FLOWER EXTRACT	0	100%	none identified
CARBOMER	0	93%	none identified
SODIUM CHLORIDE	0	0%	innocuous
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		DNA
One or more in vitro tests on mammalian cells show positive mutation results		PROPYLPARABEN, SODIUM CHLORIDE, GLYCERIN, SODIUM HYDROXIDE, METHYLPARABEN

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at moderate doses		GLYCERIN
One or more animal studies show reproductive effects at high doses		POLYSORBATE-20
One or more animal studies show any effects at low doses		PROPYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN
One or more animal studies show brain and nervous system effects at moderate doses		METHYLPARABEN
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		PROPYLPARABEN
One or more animal studies show endocrine system disruption at high doses		GLYCERIN
Human any disruptor - strong evidence		METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human immune system toxicant - moderate evidence		PECTIN
Human skin toxicant - strong evidence		PROPYLPARABEN, METHYLPARABEN

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	SODIUM CHLORIDE
One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient)		POLYSORBATE-20
Limited evidence of sense organ toxicity		PROPYLPARABEN
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, SODIUM HYDROXIDE
Known human any toxicant		METHYLPARABEN
Possible human immune system toxicant		PECTIN

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		PROPYLPARABEN
Not suspected to be an environmental toxin		SODIUM HYDROXIDE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at very low doses		SODIUM HYDROXIDE
One or more animal studies show skin irritation at low doses		METHYLPARABEN
One or more animal studies show skin irritation at moderate doses		GLYCERIN, POLYSORBATE-20, SODIUM CHLORIDE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PROPYLPARABEN, POLYSORBATE-20
Not assessed for safety in cosmetics by industry panel		DNA, GLYCERIN, PECTIN, SODIUM HYDROXIDE, GARDENIA FLORIDA EXTRACT
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		CARBOMER, METHYLPARABEN

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
No workplace limits set		SODIUM HYDROXIDE
Allowed workplace exposures restricted to moderate doses		GLYCERIN

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		GLYCERIN
Interferes with gene expresion		METHYLPARABEN