

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Biochemical or cellular level changes |
Ingredients from packaging: PURIFIED WATER, APPLE CIDER, SODIUM BICARBONATE, BIO-IDENICAL PLANT PROTEIN EXTRACT, PLACENTA EXTRACT, CACTACEAE (CACTUS) EXTRACT, MACROCYSTIS (SEAWEED) EXTRACT, XANTHAN GUM, PROPYLENE GLYCOL, DIAZOLIDINYL UREA, METHYLPARABEN, PROPYLPARABEN, POTASSIUM SORBATE, FD&C YELLOW #6.
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| DIAZOLIDINYL UREA | 6 | 59% | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| PLACENTAL EXTRACT PLACENTA EXTRACT | 5 | 75% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (PROGESTERONE, ESTROGEN, ESTRONE) |
| PROPYLPARABEN | 5 | 71% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| UNSPECIFIED EXTRACTS BIO-IDENICAL PLANT PROTEIN EXTRACT | 4 | 100% | Miscellaneous |
| FD&C YELLOW 6 | 1 | 70% | none identified |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| SODIUM BICARBONATE | 2 | 80% | none identified |
| POTASSIUM SORBATE | 1 | 85% | none identified |
| PYRUS MALUS (APPLE) JUICE APPLE CIDER | 0 | 100% | none identified |
| MACROCYSTIS PYRIFERA EXTRACT MACROCYSTIS (SEAWEED) EXTRACT | 0 | 100% | none identified |
| CACTACEAE (CACTUS) EXTRACT | 0 | 100% | none identified |
| XANTHAN GUM | 0 | 94% | none identified |
| WATER (PURIFIED) | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM BICARBONATE, PROPYLENE GLYCOL, PROPYLPARABEN, POTASSIUM SORBATE | |
| Cancer - not classifiable/not likely to be human carcinogen | FD&C YELLOW 6 | |
| One or more in vitro tests on mammalian cells show positive mutation results | DIAZOLIDINYL UREA, METHYLPARABEN |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive system effects at high doses | FD&C YELLOW 6 | |
| One or more animal studies show reproductive effects at moderate doses | SODIUM BICARBONATE | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PROPYLENE GLYCOL, DIAZOLIDINYL UREA | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | PLACENTAL EXTRACT | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | PROPYLENE GLYCOL, SODIUM BICARBONATE, POTASSIUM SORBATE, FD&C YELLOW 6, DIAZOLIDINYL UREA | |
| One or more animal studies show brain and nervous system effects at moderate doses | METHYLPARABEN |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more studies show weak endocrine disruption | PLACENTAL EXTRACT | |
| One or more animal studies show endocrine system disruption at high doses | DIAZOLIDINYL UREA | |
| Human any disruptor - strong evidence | PROPYLPARABEN, METHYLPARABEN |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human skin toxicant - strong evidence | PROPYLPARABEN, METHYLPARABEN | |
| Known human immune system toxicant | DIAZOLIDINYL UREA |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | PROPYLENE GLYCOL, FD&C YELLOW 6, DIAZOLIDINYL UREA | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | POTASSIUM SORBATE, SODIUM BICARBONATE | |
| Known human any toxicant | METHYLPARABEN | |
| Limited evidence of sense organ toxicity | PROPYLPARABEN | |
| Potential risk of infectious disease - any | PLACENTAL EXTRACT |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | UNSPECIFIED EXTRACTS |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | PROPYLPARABEN |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | SODIUM BICARBONATE | |
| One or more animal studies show skin irritation at low doses | METHYLPARABEN | |
| Classified as skin irritant | PROPYLENE GLYCOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL | |
| Insufficient data to determine safety | PLACENTAL EXTRACT | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | POTASSIUM SORBATE, SODIUM BICARBONATE, PROPYLPARABEN, METHYLPARABEN | |
| Not assessed for safety in cosmetics by industry panel | CACTACEAE (CACTUS) EXTRACT, MACROCYSTIS PYRIFERA EXTRACT, XANTHAN GUM, UNSPECIFIED EXTRACTS, PYRUS MALUS (APPLE) JUICE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | SODIUM BICARBONATE, PROPYLENE GLYCOL | |
| Interferes with gene expresion | METHYLPARABEN |
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