Revision 8% Skin Lightening Gel || Skin Deep: Cosmetic Safety Reviews

REVISION 8% SKIN LIGHTENING GEL

last updated: 02/12/10 brand: Revision by Revision Skincare

SCORE

moderate hazard (out of 10)

90%

data gap

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49% of anti-agings have lower concerns
28% of skin fading/lighteners have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards

Ingredients from packaging: CYCLOMETHICONE, PETROLATUM, POLYSILICONE-11, KOJIC ACID, KOJIC DIPALMITATE, HYDROQUINONE, L-ASCORBIC ACID, SQUALANE, TOCOPHERYL ACETATE, WHEAT GERM EXTRACT, SUNFLOWER EXTRACT, BARLEY EXTRACT, LICORICE EXTRACT.

Directions from packaging: Apply once or twice daily to clean skin and allow to absorb. Wait 10 minutes before applying makeup. Caution: For external use only. Avoid the eye area. If irritation or reddening occurs and persists discontinue use.

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ingredients

	score	data gap	concerns
HYDROQUINONE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
PETROLATUM	2	94%	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
SQUALANE	1	93%	Irritation (skin, eyes, or lungs)
ASCORBIC ACID (VITAMIN C) L-ASCORBIC ACID	1	91%	none identified
KOJIC ACID	1	82%	none identified
GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT LICORICE EXTRACT	0	100%	none identified
HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT SUNFLOWER EXTRACT	0	100%	none identified
HORDEUM VULGARE (BARLEY) EXTRACT	0	100%	none identified
KOJIC DIPALMITATE	0	100%	none identified
POLYSILICONE-11	0	100%	none identified
TRITICUM VULGARE (WHEAT) GERM EXTRACT	0	100%	none identified

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHERYL ACETATE, ASCORBIC ACID (VITAMIN C)
Cancer - not classifiable/not likely to be human carcinogen		KOJIC ACID
Limited evidence of carcinogenicity		HYDROQUINONE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human nervous system toxicant - moderate evidence		HYDROQUINONE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		HYDROQUINONE, HYDROQUINONE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		HYDROQUINONE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Safe for brief discontinuous use followed by thorough rinsing	products that are intended to be left on the skin	HYDROQUINONE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at moderate doses		KOJIC ACID
Strong evidence of human neurotoxicity		HYDROQUINONE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		KOJIC ACID, HYDROQUINONE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE
Known human immune system toxicant		HYDROQUINONE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		PETROLATUM
Not suspected to be persistent		HYDROQUINONE
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		PETROLATUM
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		CYCLOMETHICONE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		TOCOPHERYL ACETATE, KOJIC ACID
Known human respiratory toxicant		HYDROQUINONE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		CYCLOMETHICONE
Not suspected to be an environmental toxin		PETROLATUM
Wildlife and environmental toxicity		HYDROQUINONE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		CYCLOMETHICONE
One or more animal studies show skin irritation at low doses		SQUALANE
One or more animal studies show skin irritation at very low doses		HYDROQUINONE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHERYL ACETATE
Not assessed for safety in cosmetics by industry panel		POLYSILICONE-11, SQUALANE, TRITICUM VULGARE (WHEAT) GERM EXTRACT
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		ASCORBIC ACID (VITAMIN C), CYCLOMETHICONE
Not assessed for safety in cosmetics by industry panel		PETROLATUM, KOJIC DIPALMITATE, KOJIC ACID, HORDEUM VULGARE (BARLEY) EXTRACT, HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT, GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT
Safety assessment was based on related chemical		ASCORBIC ACID (VITAMIN C)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		HYDROQUINONE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CYCLOMETHICONE