Pro-Line No-Lye Conditioning Cream Relaxer with HMC Children's Regular Formula Kit (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

PRO-LINE NO-LYE CONDITIONING CREAM RELAXER WITH HMC CHILDREN'S REGULAR FORMULA KIT (2006 FORMULATION)

last updated: 05/01/06 brand: Pro-Line by Pro-Line International

SCORE

high hazard (out of 10)

81%

data gap

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COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: WATER AQUA, PROPYLENE GLYCOL, HYDROXYETHYLCELLULOSE, HELIANTHUS ANNUUS EXTRACT SUNFLOWER, SALVIA OFFICINALIS LEAF EXTRACT SAGE, SYMPHYTUM OFFICINALE LEAF EXTRACT, ACHILLEA MILLEFOLIUM EXTRACT, LACTIC ACID, METHYLPARABEN, PROPYLPARABEN, DIAZOLIDINYL UREA, FRAGRANCE PARFUM, WATER AQUA, PETROLATUM, CETEARYL ALCOHOL, MINERAL OIL PARAFFINUM LIQUIDUM, POLYSORBATE 60, CALCIUM HYDROXIDE, PROPYLENE GLYCOL, PEG-75 LANOLIN, SODIUM STEAROAMPHOACETATE, OLETH-3 PHOSPHATE, FRAGRANCE PARFUM, WATER AQUA, GUANIDINE CARBONATE, SORBITOL, DENATONIUM BENZOATE, WATER AQUA, DISODIUM COCOAMPHODIPROPIONATE, POLYQUATERNIUM-7, SODIUM LAURETH SULFATE, LAURAMIDE DEA, CITRIC ACID, TETRASODIUM EDTA, POLYSORBATE 20, PEG-150 DISTEARATE, METHYLPARABEN, DIAZOLIDINYL UREA, PHENOLSULFONPHTHALEIN, FRAGRANCE PARFUM, WATER AQUA, MINERAL OIL PARAFFINUM LIQUIDUM, PANTHENOL, ACETAMIDE MEA, HYDROLYZED KERATIN, HYDROLYZED GLYCOSAMINOGLYCANS SODIUM COCOYL COLLAG, HYDROXYETHYLCELLULOSE, SORBITAN STEARATE, POLYQUATERNIUM-22, OLETH-3 PHOSPHATE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, FRAGRANCE PARFUM, WATER AQUA, MINERAL OIL PARAFFINUM LIQUIDUM, LANOLIN, LANOLIN OIL, PETROLATUM, C12-15 ALKYL BENZOATE, HYDROXYLATED LANOLIN, PANTHENOL, SORBITAN OLEATE, SODIUM BORATE, PROPYLPARABEN, DIAZOLIDINYL UREA, FRAGRANCE PARFUM, RED 33 CI 17200, MINERAL OIL PARAFFINUM LIQUIDUM, CERESIN, PETROLATUM .

Warnings from packaging: This product is not a toy. Read instructions inside kit carton carefully before using. Keep out of reach of children. Use only as directed. If accidentally swallowed, consult a physician immediately. Wear gloves when mixing or applying. This product should be applied by an adult. Adult supervision during the mixing, application and clean up of this product is required. 1. This product contains Calcium Hydroxide and Guanidine Carbonate - toxic. You must follow directions carefully to avoid skin and scalp burns, hair loss and eye injury. 2. Keep this product and others away from eyes and mouth. If product gets into eye, rinse immediately and consult a physician. 3. Do not use if scalp is irritated or injured. 4. If hair has been previously relaxed, relax only the new growth as described in the instructions. 5. If relaxer causes skin or scalp irritation, rinse out immediately and wash with an acid-balanced shampoo. If irritation persists or if hair loss occurs, consult a physician. 6. Do not use on bleached hair. Do not use on permanently colored hair that is breaking, splitting or otherwise damaged. 7. Do not use on curly permed or permanently waved hair until it has grown out. Not recommended for children under 6 years of age.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
SODIUM BORATE	6	51%	Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Occupational hazards
PEG-75 LANOLIN	4	75%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-150 DISTEARATE	4	73%	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
METHYLCHLOROISOTHIAZOLINONE	6	63%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
METHYLISOTHIAZOLINONE	6	63%	Violations, restrictions & warnings, Allergies/immunotoxicity
DIAZOLIDINYL UREA	6	59%	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
LACTIC ACID	4	70%	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs)
DISODIUM COCOAMPHODIPROPIONATE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
SODIUM LAURETH SULFATE	4	88%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
MINERAL OIL	2	73%	Organ system toxicity (non-reproductive), Occupational hazards
LANOLIN	4	71%	Allergies/immunotoxicity
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
OLETH-3 PHOSPHATE	3	94%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT ACHILLEA MILLEFOLIUM EXTRACT	3	89%	Allergies/immunotoxicity, Multiple, additive exposure sources
CITRIC ACID	2	72%	Violations, restrictions & warnings
LAURAMIDE DEA	3	70%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES)
PETROLATUM	2	94%	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
POLYQUATERNIUM-7	2	93%	Contamination concerns (ACRYLAMIDE)
PANTHENOL	2	88%	Multiple, additive exposure sources
CALCIUM HYDROXIDE	1	83%	Occupational hazards
TETRASODIUM EDTA	2	81%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
HYDROLYZED KERATIN	2	75%	Violations, restrictions & warnings
ACETAMIDE MEA	1	73%	Contamination concerns (ACETAMIDE MEA)
SALVIA OFFICINALIS (SAGE) LEAF EXTRACT SALVIA OFFICINALIS LEAF EXTRACT SAGE	1	95%	none identified
SYMPHYTUM OFFICINALE (COMFREY) LEAF EXTRACT SYMPHYTUM OFFICINALE LEAF EXTRACT	1	95%	Organ system toxicity (non-reproductive)
C12-15 ALKYL BENZOATE	0	94%	none identified
CERESIN	0	93%	none identified
CETEARYL ALCOHOL	0	93%	none identified
SORBITAN STEARATE	1	92%	none identified
DENATONIUM BENZOATE	1	90%	none identified
GUANIDINE CARBONATE	1	89%	none identified
PHENOLSULFONPHTHALEIN	1	88%	Organ system toxicity (non-reproductive)
SORBITOL	1	88%	none identified
SORBITAN OLEATE	1	86%	none identified
POLYSORBATE-20	1	84%	none identified
HYDROXYETHYLCELLULOSE	1	82%	none identified
POLYSORBATE-60	1	81%	none identified
HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT HELIANTHUS ANNUUS EXTRACT SUNFLOWER	0	100%	none identified
HYDROLYZED GLYCOSAMINOGLYCANS	0	100%	none identified
POLYQUATERNIUM-22	0	100%	none identified
SODIUM COCOYL COLLAGEN AMINO ACID HYDROLYZED GLYCOSAMINOGLYCANS SODIUM COCOYL COLLAG	0	100%	none identified
SODIUM STEAROAMPHOACETATE	0	94%	none identified
HYDROXYLATED LANOLIN	0	93%	none identified
LANOLIN OIL	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		POLYSORBATE-60, MINERAL OIL, LAURAMIDE DEA
One or more in vitro tests non-mammalian cells show positive mutation results		SODIUM BORATE, PHENOLSULFONPHTHALEIN, METHYLCHLOROISOTHIAZOLINONE
One or more in vitro tests on mammalian cells show positive mutation results		SORBITOL, PROPYLENE GLYCOL, PROPYLPARABEN, SALVIA OFFICINALIS (SAGE) LEAF EXTRACT, SORBITAN OLEATE, METHYLPARABEN, DIAZOLIDINYL UREA, CALCIUM HYDROXIDE
Cancer - not classifiable/not likely to be human carcinogen		LACTIC ACID

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		POLYSORBATE-60, POLYSORBATE-20, HYDROXYETHYLCELLULOSE
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL
One or more animal studies show any effects at low doses		PROPYLPARABEN
Limited evidence of reproductive toxicity		SODIUM BORATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-75 LANOLIN
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, SODIUM BORATE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ACETAMIDE MEA, DIAZOLIDINYL UREA, DISODIUM COCOAMPHODIPROPIONATE, LACTIC ACID, LAURAMIDE DEA, METHYLCHLOROISOTHIAZOLINONE, SODIUM BORATE, PROPYLENE GLYCOL, PEG-150 DISTEARATE, METHYLISOTHIAZOLINONE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - concentration limit in some types of cosmetics when combined with certain other ingredient(s)		METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, LACTIC ACID, HYDROLYZED KERATIN, CITRIC ACID
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits		LACTIC ACID
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells demonstrate neurotoxicity		METHYLISOTHIAZOLINONE
One or more animal studies show brain and nervous system effects at high doses		SODIUM BORATE, PROPYLENE GLYCOL, LACTIC ACID, HYDROXYETHYLCELLULOSE, DIAZOLIDINYL UREA
One or more animal studies show brain and nervous system effects at moderate doses		DENATONIUM BENZOATE, METHYLPARABEN
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		SODIUM BORATE, DIAZOLIDINYL UREA
Human any disruptor - strong evidence		METHYLPARABEN, PROPYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		PROPYLPARABEN, METHYLPARABEN, ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT
Known human immune system toxicant		METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, LANOLIN, FRAGRANCE, DISODIUM COCOAMPHODIPROPIONATE, DIAZOLIDINYL UREA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		PETROLATUM
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		PROPYLENE GLYCOL, SORBITAN OLEATE, SORBITOL, POLYSORBATE-20, HYDROXYETHYLCELLULOSE, PANTHENOL, MINERAL OIL, DIAZOLIDINYL UREA, CALCIUM HYDROXIDE, ACETAMIDE MEA
One or more animal studies show kidney or renal system effects at moderate doses (low dose studies may be unavailable for this ingredient)		TETRASODIUM EDTA, SODIUM LAURETH SULFATE, POLYSORBATE-60, LACTIC ACID, GUANIDINE CARBONATE, CITRIC ACID, LAURAMIDE DEA
Limited evidence of sense organ toxicity		PROPYLPARABEN, PEG-75 LANOLIN, PEG-150 DISTEARATE
One or more animal studies show broad systemic effects at low doses		SODIUM BORATE
One or more animal studies show kidney or renal system effects at very low doses		PHENOLSULFONPHTHALEIN
Possible human immune system toxicant		METHYLCHLOROISOTHIAZOLINONE
Limited evidence of any toxicity		SYMPHYTUM OFFICINALE (COMFREY) LEAF EXTRACT
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Prohibited for use in food		SODIUM BORATE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PEG-75 LANOLIN, TETRASODIUM EDTA, SORBITOL, SORBITAN STEARATE, SORBITAN OLEATE, PROPYLPARABEN, PROPYLENE GLYCOL, POLYSORBATE-60, POLYSORBATE-20, PETROLATUM, LANOLIN, MINERAL OIL, PEG-150 DISTEARATE, METHYLPARABEN, LAURAMIDE DEA, LACTIC ACID, CITRIC ACID, CALCIUM HYDROXIDE
Used in food or as an additive with limited or no toxicity information available		SODIUM BORATE, ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT, PANTHENOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be an environmental toxin		SODIUM BORATE, PETROLATUM
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		SORBITAN STEARATE, SORBITAN OLEATE, POLYSORBATE-20, MINERAL OIL, CITRIC ACID
One or more animal studies show skin irritation at low doses		TETRASODIUM EDTA
One or more animal studies show skin irritation at moderate doses		ACETAMIDE MEA
One or more animal studies show skin irritation at low doses		METHYLPARABEN
One or more animal studies show skin irritation at very low doses		LAURAMIDE DEA, LACTIC ACID
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	SODIUM LAURETH SULFATE
Classified as skin irritant		PROPYLENE GLYCOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PEG-150 DISTEARATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TETRASODIUM EDTA
Insufficient data to determine safety		ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT
Safety assessment was based on related chemical		PEG-75 LANOLIN
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PROPYLPARABEN, SODIUM LAURETH SULFATE, SORBITAN OLEATE, PEG-75 LANOLIN
Safety assessment was based on related chemical		PROPYLENE GLYCOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		POLYSORBATE-60, POLYSORBATE-20, PEG-150 DISTEARATE, SORBITAN STEARATE, METHYLPARABEN, POLYQUATERNIUM-7, PANTHENOL, LAURAMIDE DEA, LANOLIN, HYDROXYETHYLCELLULOSE, LANOLIN OIL, DISODIUM COCOAMPHODIPROPIONATE, HYDROXYLATED LANOLIN, CERESIN, CETEARYL ALCOHOL
Not assessed for safety in cosmetics by industry panel		SYMPHYTUM OFFICINALE (COMFREY) LEAF EXTRACT, SORBITOL, SODIUM STEAROAMPHOACETATE, SODIUM COCOYL COLLAGEN AMINO ACID, SALVIA OFFICINALIS (SAGE) LEAF EXTRACT, POLYQUATERNIUM-22, PHENOLSULFONPHTHALEIN, PETROLATUM, OLETH-3 PHOSPHATE, MINERAL OIL, HYDROLYZED KERATIN, HYDROLYZED GLYCOSAMINOGLYCANS, HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT, GUANIDINE CARBONATE, FRAGRANCE, DENATONIUM BENZOATE, CITRIC ACID, CALCIUM HYDROXIDE, C12-15 ALKYL BENZOATE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		SODIUM BORATE
Allowed workplace exposures restricted to moderate doses		CALCIUM HYDROXIDE, MINERAL OIL
No workplace limits set		LACTIC ACID
Allowed workplace exposures restricted to low doses		TETRASODIUM EDTA

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		LAURAMIDE DEA
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, PROPYLENE GLYCOL
Interferes with gene expresion		METHYLPARABEN