

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: INGREDIENTS: 4 OZ: WATER (AQUA PURIFICANTE), CYCLOMETHICONE, ISOHEXADECANE, ISODODECANE, BUTYLENE GLYCOL, SODIUM CHLORIDE, POLOXAMER 184, BENZYL ALCOHOL, DISODIUM EDTA, DMDM HYDANTOIN, TODOPROPYNYL BUTYLCARBAMATE.
| score | data gap | concerns | |
| DMDM HYDANTOIN | 7 | 71% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE) |
| POLOXAMER 184 | 7 | 82% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (ACETIC ACID, FORMIC ACID, PROPYLENE OXIDE, ETHYLENE OXIDE, 1,4-DIOXANE, ALDEHYDES) |
| IODOPROPYNYL BUTYLCARBAMATE TODOPROPYNYL BUTYLCARBAMATE | 4 | 65% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| BENZYL ALCOHOL | 6 | 64% | Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| DISODIUM EDTA | 3 | 78% | Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption |
| CYCLOMETHICONE | 2 | 83% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| ISOHEXADECANE | 0 | 94% | none identified |
| BUTYLENE GLYCOL | 1 | 79% | Irritation (skin, eyes, or lungs) |
| ISODODECANE | 0 | 100% | none identified |
| SODIUM CHLORIDE | 0 | 0% | innocuous |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | SODIUM CHLORIDE, DISODIUM EDTA, BENZYL ALCOHOL |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | DISODIUM EDTA, BENZYL ALCOHOL, BUTYLENE GLYCOL |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | IODOPROPYNYL BUTYLCARBAMATE, BENZYL ALCOHOL | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | BENZYL ALCOHOL, BENZYL ALCOHOL | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | IODOPROPYNYL BUTYLCARBAMATE, DMDM HYDANTOIN, DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | POLOXAMER 184 | |
| Strong evidence of human neurotoxicity | BENZYL ALCOHOL | |
| One or more animal studies show brain and nervous system effects at high doses | BUTYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at low doses | DISODIUM EDTA |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | DISODIUM EDTA, BUTYLENE GLYCOL |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more human case studies show possible allergenic effects | BENZYL ALCOHOL | |
| Human any toxicant - strong evidence | IODOPROPYNYL BUTYLCARBAMATE | |
| Known human immune system toxicant | DMDM HYDANTOIN |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | POLOXAMER 184 | |
| Persistent, bioaccumulative in wildlife | CYCLOMETHICONE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | BENZYL ALCOHOL | |
| One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) | products for use around the eyes, mouth, or lips | CYCLOMETHICONE, BUTYLENE GLYCOL |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | DMDM HYDANTOIN | |
| Limited evidence of gastrointestinal or liver toxicity | IODOPROPYNYL BUTYLCARBAMATE | |
| One or more animal studies show sense organ effects at low doses | products for use around the eyes, mouth, or lips | SODIUM CHLORIDE |
| One or more animal studies show broad systemic effects at low doses | POLOXAMER 184, DISODIUM EDTA |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | CYCLOMETHICONE, POLOXAMER 184 |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at high doses | IODOPROPYNYL BUTYLCARBAMATE | |
| One or more animal studies show skin irritation at moderate doses | SODIUM CHLORIDE, CYCLOMETHICONE | |
| One or more animal studies show skin irritation at low doses | BENZYL ALCOHOL | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | DMDM HYDANTOIN, BUTYLENE GLYCOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | IODOPROPYNYL BUTYLCARBAMATE, POLOXAMER 184 | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | POLOXAMER 184 | |
| Missing safety data noted by cosmetic industry review | POLOXAMER 184 | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DMDM HYDANTOIN, CYCLOMETHICONE, DISODIUM EDTA, BUTYLENE GLYCOL | |
| Not assessed for safety in cosmetics by industry panel | ISOHEXADECANE, ISODODECANE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | BENZYL ALCOHOL |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CYCLOMETHICONE |
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