Biotherm Line Peel Eye Gentle Wrinkle Corrector (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

BIOTHERM LINE PEEL EYE GENTLE WRINKLE CORRECTOR (2006 FORMULATION)

last updated: 05/01/06 brand: Biotherm by L'Oréal

SCORE

moderate hazard (out of 10)

80%

data gap

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42% of anti-agings have lower concerns
43% of around-eye creams have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: INGREDIENTS: 0.5 OZ: WATER, GLYCERIN, CYCLOHEXASILOXANE, NYLON-66, PENTAERYTHRITYL TETRAETHYLHEXANOATE, AMMONIUM POLYACRYLOYLDIMETHYL TAURATE, STEARIC ACID, STEARYL ALCOHOL, TALC, CETYL ALCOHOL, SQUALANE, HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID, BIOSACCHARIDE GUM-1, METHYLSILANOL MANNURONATE, HYDROXYPROLINE, ADENOSINE, VITREOSCILLA FERMENT, ZEA MAYS (CORN) OIL, PRUNUS ARMENIACA (APRICOT KERNEL) OIL, PASSIFLORA EDULIS SEED OIL, ORYZA SATIVA (RICE BRAN) OIL, MICA, SILICA, TITANIUM DIOXIDE, PEG-100 STEARATE, GLYCERYL STEARATE, PALMITIC ACID, MYRISTIC ACID, TRIETHANOLAMINE, PHENOXYETHANOL, CHLORPHENESIN, METHYLPARABEN, ISOBUTYLPARABEN, ETHYLPARABEN, PROPYLPARABEN, BUTYLPARABEN.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
SILICA	1	69%	Biochemical or cellular level changes
PEG-100 STEARATE	4	69%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
BUTYLPARABEN	6	79%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
TRIETHANOLAMINE	6	58%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ETHYLPARABEN	5	80%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
TITANIUM DIOXIDE (NON-NANO)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
ADENOSINE	4	81%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
ORYZA SATIVA (RICE) BRAN OIL	4	74%	Contamination concerns (GOSSYPOL, HEAVY METALS, ORGANOCHLORINES, PESTICIDES)
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
TALC	3	86%	Organ system toxicity (non-reproductive), Contamination concerns (ASBESTIFORM FIBERS), Occupational hazards
ISOBUTYLPARABEN	3	83%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
MICA	3	75%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
CYCLOHEXASILOXANE	1	82%	Persistence and bioaccumulation
ZEA MAYS (CORN) OIL	2	79%	Neurotoxicity
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
MYRISTIC ACID	2	74%	Neurotoxicity, Irritation (skin, eyes, or lungs)
STEARIC ACID	2	74%	Neurotoxicity, Irritation (skin, eyes, or lungs)
CHLORPHENESIN	2	72%	Violations, restrictions & warnings
NYLON-66	1	94%	Organ system toxicity (non-reproductive)
SQUALANE	1	93%	Irritation (skin, eyes, or lungs)
HYDROXYPROLINE	1	92%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
STEARYL ALCOHOL	1	84%	Irritation (skin, eyes, or lungs)
PALMITIC ACID	1	76%	Neurotoxicity
AMMONIUM POLYACRYLOYLDIMETHYL TAURATE	0	100%	none identified
METHYLSILANOL MANNURONATE	0	100%	none identified
PENTAERYTHRITYL TETRAETHYLHEXANOATE	0	100%	none identified
VITREOSCILLA FERMENT	0	100%	none identified
BIOSACCHARIDE GUM-1	0	100%	none identified
PASSIFLORA EDULIS (PASSION FRUIT) SEED OIL PASSIFLORA EDULIS SEED OIL	0	94%	none identified
PRUNUS ARMENIACA (APRICOT) KERNEL OIL	0	94%	none identified
HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID	0	94%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		ZEA MAYS (CORN) OIL, STEARYL ALCOHOL
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL
One or more animal studies show tumor formation at moderate doses		PEG-100 STEARATE
One or more in vitro tests on mammalian cells show positive mutation results		ADENOSINE, TITANIUM DIOXIDE (NON-NANO), PROPYLPARABEN, METHYLPARABEN, HYDROXYPROLINE, GLYCERIN, ETHYLPARABEN, BUTYLPARABEN
Not likely to be carcinogenic in humans		STEARIC ACID, PALMITIC ACID, MYRISTIC ACID
Cancer - not classifiable/not likely to be human carcinogen		TRIETHANOLAMINE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		PEG-100 STEARATE, ZEA MAYS (CORN) OIL, ETHYLPARABEN
One or more animal studies show reproductive effects at moderate doses		GLYCERIN
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at very low doses		ADENOSINE,
One or more animal studies show any effects at very low doses		BUTYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-100 STEARATE, TRIETHANOLAMINE, ORYZA SATIVA (RICE) BRAN OIL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		CHLORPHENESIN, PHENOXYETHANOL, CHLORPHENESIN
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN
One or more animal studies show brain and nervous system effects at low doses		ZEA MAYS (CORN) OIL
One or more animal studies show brain and nervous system effects at moderate doses		CHLORPHENESIN, PHENOXYETHANOL, METHYLPARABEN
One or more animal studies show brain and nervous system effects at low doses		PALMITIC ACID, MYRISTIC ACID
One or more animal studies show brain and nervous system effects at very low doses		ADENOSINE, STEARIC ACID

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		TRIETHANOLAMINE
Human any disruptor - strong evidence		BUTYLPARABEN, ETHYLPARABEN, PROPYLPARABEN
One or more animal studies show endocrine disruption at moderate doses		ISOBUTYLPARABEN
One or more animal studies show endocrine system disruption at high doses		CYCLOHEXASILOXANE, GLYCERIN
Human any disruptor - strong evidence		METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more animal studies show gastrointestinal effects at moderate doses		MICA
Human skin toxicant - strong evidence		ISOBUTYLPARABEN, METHYLPARABEN, PROPYLPARABEN
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Known human immune system toxicant		TRIETHANOLAMINE
Human skin toxicant - strong evidence		BUTYLPARABEN, ETHYLPARABEN

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be persistent		CETYL ALCOHOL
Not suspected to be bioaccumulative		NYLON-66, TALC, TITANIUM DIOXIDE (NON-NANO), TRIETHANOLAMINE
Persistent, bioaccumulative in wildlife and humans		MICA
Persistent, bioaccumulative in wildlife		CYCLOHEXASILOXANE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	STEARYL ALCOHOL, MYRISTIC ACID
Classified as expected to be toxic or harmful		TALC, NYLON-66
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		CYCLOHEXASILOXANE, STEARIC ACID
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	SILICA
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		ZEA MAYS (CORN) OIL
Limited evidence of sense organ toxicity		PEG-100 STEARATE
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CETYL ALCOHOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		GLYCERYL MONOSTEARATE
Limited evidence of sense organ toxicity		PROPYLPARABEN, ISOBUTYLPARABEN, ETHYLPARABEN, BUTYLPARABEN
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	PHENOXYETHANOL
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, ADENOSINE, TITANIUM DIOXIDE (NON-NANO)
Possible human respiratory toxicant		MICA, TRIETHANOLAMINE
Known human any toxicant		METHYLPARABEN

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be an environmental toxin		TRIETHANOLAMINE
Suspected to be an environmental toxin		CETYL ALCOHOL
Not suspected to be an environmental toxin		TITANIUM DIOXIDE (NON-NANO), NYLON-66, TALC
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		PHENOXYETHANOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	STEARYL ALCOHOL
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL, TRIETHANOLAMINE, PEG-100 STEARATE
One or more animal studies show skin irritation at low doses		METHYLPARABEN, MYRISTIC ACID, SQUALANE, STEARIC ACID
One or more animal studies show skin irritation at moderate doses		BUTYLPARABEN, GLYCERIN, PALMITIC ACID, TALC, TITANIUM DIOXIDE (NON-NANO), ZEA MAYS (CORN) OIL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		MYRISTIC ACID, PEG-100 STEARATE, ISOBUTYLPARABEN
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PEG-100 STEARATE, ORYZA SATIVA (RICE) BRAN OIL, STEARIC ACID, STEARYL ALCOHOL, PROPYLPARABEN, PHENOXYETHANOL, PALMITIC ACID, MYRISTIC ACID, METHYLPARABEN, GLYCERYL MONOSTEARATE
Not assessed for safety in cosmetics by industry panel		AMMONIUM POLYACRYLOYLDIMETHYL TAURATE, CHLORPHENESIN, CYCLOHEXASILOXANE, GLYCERIN, HYDROXYPROLINE, METHYLSILANOL MANNURONATE, NYLON-66, PASSIFLORA EDULIS (PASSION FRUIT) SEED OIL, PENTAERYTHRITYL TETRAETHYLHEXANOATE, PRUNUS ARMENIACA (APRICOT) KERNEL OIL, SQUALANE, TALC, TITANIUM DIOXIDE (NON-NANO), VITREOSCILLA FERMENT, ZEA MAYS (CORN) OIL, ADENOSINE, BIOSACCHARIDE GUM-1, HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BUTYLPARABEN, CETYL ALCOHOL, ETHYLPARABEN

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		TRIETHANOLAMINE
Allowed workplace exposures restricted to low doses		TALC, MICA
Allowed workplace exposures restricted to moderate doses		GLYCERIN
Allowed workplace exposures restricted to low doses		PHENOXYETHANOL, TITANIUM DIOXIDE (NON-NANO)

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ZEA MAYS (CORN) OIL
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		GLYCERIN
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		ADENOSINE, SILICA, TITANIUM DIOXIDE (NON-NANO)