Donate Skin Deep

ESTéE LAUDER RE-NUTRIV INTENSIVE LIFTING HAND CREAM, SPF 15 (2005 FORMULATION)

last updated: 04/01/05 brand: Estée Lauder by Estée Lauder

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.


Sunscreens: What's Safe & What Works

Sunscreen effectiveness* breakdown

6UVB hazard/exposure score
8UVA hazard/exposure score
5sunscreen instability

*Note that the same active ingredient combination may score differently in two different products depending on the concentration of the ingredients and the mixture of inactive ingredients.


Active ingredient UV
blocking strength

Product total
OCTINOXATE (OCTYL METHOXYCINNAMATE) (7.5%) 
OCTISALATE (3%) 
OXYBENZONE (BENZOPHENONE-3) (2%) 

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.


Ingredients in this product are linked to:
noCancer
yesDevelopmental/reproductive toxicity
yesViolations, restrictions & warnings
yesAllergies/immunotoxicity
yesOther concerns for ingredients used in this product:
Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes


Ingredients from packaging: OCTINOXATE 7.50%; OCTISALATE 3.00%; OXYBENZONE 2.00%; WATER (AQUA PURIFICATA) PURIFIED; GLYCERIN; GLYCERYL; STEARATE; STEARIC ACID; DIMETHICONE; DICAPRYLYL MALEATE; CYCLOPENTASILOXANE; PENTYLENE GLYCOL; BUTYLENE GLYCOL; SCUTELLARIA BAICALENSIS EXTRACT; PORIA COCOS EXTRACT; SALVIA SCLAREA (CLARY) EXTRACT; PALMITOYL PENTAPEPTIDE-3; BETULA ALBA (BIRCH) EXTRACT; HORDEUM VULGARE (BARLEY) EXTRACT; TRITICUM VULGARE (WHEAT) GERM EXTRACT; GLYCINE; ALGAE EXTRACT; MORUS NIGRA (MULBERRY) ROOT EXTRACT; DIETHYLHEXYL 2,6-NAPHTHALATE; CALLUNA VULGARIS (HEATHER) EXTRACT [SUCROSE; PHYTOSPHINGOSINE; ACETYL GLUCOSAMINE; TRIUNDECANOIN; TOCOPHERYL ACETATE; LINOLEIC ACID; CHOLESTEROL; VITIS VINIFERA (GRAPE) FRUIT EXTRACT; TOCOQUINONE; SQUALANE; ASCORBYL GLUCOSIDE; PENTAERYTHRITYL TETRAOCTANOATE; SYNTHETIC WAX; GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT; STEARYL ALCOHOL; HYDROLYZED WHEAT PROTEIN; POLYDECENE; CETEARETH-20; MAGNESIUM ALUMINUM SILICATE; AMINOMETHYL PROPANOL; CETYL ACETATE; POLYETHYLENE; PEG/PPG-20/15 DIMETHICONE; PEG-40 HYDROGENATED CASTOR OIL; PHENYL METHICONE; CERESIN; ACETYLATED LANOLIN ALCOHOL; BEESWAX (CERA ALBA); HYDROGENATED VEGETABLE OIL; CARBOMER; POLYSORBATE 20; FRAGRANCE (PARFUM); DISODIUM EDTA; SODIUM DEHYDROACETATE; PHENOXYETHANOL; METHYLPARABEN; ETHYLPARABEN; PROPYLPARABEN; BUTYLPARABEN; ISOBUTYLPARABEN; YELLOW 5 (CI 19140); YELLOW 6 (CI 15985)

 

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ingredients

     score    data gap       concerns
METHYLPARABEN1063%Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
OXYBENZONE (BENZOPHENONE-3)
(Active Ingredient)
955%Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE8100%Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20571%Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
POLYETHYLENE669%Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
OCTINOXATE (OCTYL METHOXYCINNAMATE)
(Active Ingredient)
665%Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
BUTYLPARABEN679%Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PEG-40 HYDROGENATED CASTOR OIL475%Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG/ PPG-20/ 15 DIMETHICONE475%Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ETHYLPARABEN580%Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLPARABEN571%Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
MAGNESIUM ALUMINUM SILICATE488%Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
TOCOPHERYL ACETATE481%Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
FD&C YELLOW 6170%none identified
OCTISALATE
(Active Ingredient)
368%Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PHENOXYETHANOL467%Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards
ISOBUTYLPARABEN383%Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5282%Neurotoxicity, Organ system toxicity (non-reproductive)
CYCLOPENTASILOXANE279%Persistence and bioaccumulation
DISODIUM EDTA378%Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
DIMETHICONE274%Violations, restrictions & warnings
ACETYLATED LANOLIN ALCOHOL287%Allergies/immunotoxicity
SYNTHETIC WAX179%Irritation (skin, eyes, or lungs), Occupational hazards
SODIUM DEHYDROACETATE278%Occupational hazards
BETULA ALBA (BIRCH) EXTRACT276%Violations, restrictions & warnings
CHOLESTEROL274%Persistence and bioaccumulation
GLYCERIN274%Organ system toxicity (non-reproductive), Occupational hazards
STEARIC ACID274%Neurotoxicity, Irritation (skin, eyes, or lungs)
AMINOMETHYL PROPANOL271%Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES, OXAZOLIDINE)
HYDROLYZED WHEAT PROTEIN195%Allergies/immunotoxicity
CERESIN093%none identified
CETYL ACETATE193%none identified
LINOLEIC ACID193%Irritation (skin, eyes, or lungs)
SQUALANE193%Irritation (skin, eyes, or lungs)
TOCOQUINONE190%none identified
ACETYL GLUCOSAMINE189%none identified
DICAPRYLYL MALEATE189%none identified
PENTYLENE GLYCOL189%none identified
POLYSORBATE-20184%none identified
STEARYL ALCOHOL184%Irritation (skin, eyes, or lungs)
BUTYLENE GLYCOL179%Irritation (skin, eyes, or lungs)
GLYCINE179%none identified
ASCORBYL GLUCOSIDE0100%none identified
CALLUNA VULGARIS (HEATHER) EXTRACT0100%none identified
DIETHYLHEXYL 2,6-NAPHTHALATE0100%none identified
GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT0100%none identified
HORDEUM VULGARE (BARLEY) EXTRACT0100%none identified
MORUS NIGRA (BLACK MULBERRY) ROOT EXTRACT
MORUS NIGRA (MULBERRY) ROOT EXTRACT
0100%none identified
PALMITOYL PENTAPEPTIDE-3 (MATRIXYL)0100%none identified
PENTAERYTHRITYL TETRAETHYLHEXANOATE
PENTAERYTHRITYL TETRAOCTANOATE
0100%none identified
PHENYL METHICONE0100%none identified
PHYTOSPHINGOSINE0100%none identified
POLYDECENE0100%none identified
PORIA COCOS (FU-LING) EXTRACT
PORIA COCOS EXTRACT
0100%none identified
SALVIA SCLAREA (CLARY SAGE) EXTRACT
SALVIA SCLAREA (CLARY) EXTRACT
0100%none identified
STEARATE0100%none identified
TRITICUM VULGARE (WHEAT) GERM EXTRACT0100%none identified
VITIS VINIFERA (GRAPE) FRUIT EXTRACT0100%none identified
SCUTELLARIA BAICALENSIS EXTRACT0100%none identified
ALGAE EXTRACT094%none identified
HYDROGENATED VEGETABLE OIL094%none identified
BEESWAX093%none identified
CARBOMER093%none identified
TRIUNDECANOIN092%Enhanced skin absorption
WATER00%innocuous


Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show tumor formation at high doses   STEARYL ALCOHOL
One or more in vitro tests non-mammalian cells show positive mutation results   PHENOXYETHANOL, OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show tumor formation at moderate doses   CYCLOPENTASILOXANE
One or more animal studies show tumor formation at moderate doses   SYNTHETIC WAX
One or more in vitro tests on mammalian cells show positive mutation results   TOCOPHERYL ACETATE, PROPYLPARABEN, SODIUM DEHYDROACETATE, METHYLPARABEN, GLYCINE, GLYCERIN, FD&C YELLOW 5, BUTYLPARABEN, DISODIUM EDTA, ETHYLPARABEN
Cancer - not classifiable/not likely to be human carcinogen   CHOLESTEROL, FD&C YELLOW 6, POLYETHYLENE
Not likely to be carcinogenic in humans   STEARIC ACID

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show reproductive system effects at high doses   FD&C YELLOW 6, TOCOQUINONE, FD&C YELLOW 5, POLYSORBATE-20, SODIUM DEHYDROACETATE, ETHYLPARABEN, DISODIUM EDTA, BUTYLENE GLYCOL
One or more animal studies show reproductive effects at moderate doses   OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at moderate doses   GLYCERIN, CHOLESTEROL
Limited evidence of developmental toxicity   OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show any effects at low doses   PROPYLPARABEN
One or more animal studies show any effects at very low doses   BUTYLPARABEN
Human nervous system toxicant - moderate evidence   MAGNESIUM ALUMINUM SILICATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications   POLYETHYLENE, PEG/ PPG-20/ 15 DIMETHICONE, PEG-40 HYDROGENATED CASTOR OIL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel   DIMETHICONE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications   AMINOMETHYL PROPANOL, CETEARETH-20
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only if satisfies manufacturing specifications or purity limits, according to industry safety panel (International Fragrance Association)   BETULA ALBA (BIRCH) EXTRACT
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)   OXYBENZONE (BENZOPHENONE-3), OCTISALATE, PHENOXYETHANOL
Violation of government restrictions - Banned or found unsafe for use in cosmetics   METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show brain and nervous system effects at high doses   SODIUM DEHYDROACETATE, POLYETHYLENE, PENTYLENE GLYCOL, OXYBENZONE (BENZOPHENONE-3), GLYCINE, CHOLESTEROL, FD&C YELLOW 6, GLYCERIN
One or more animal studies show brain and nervous system effects at moderate doses   METHYLPARABEN
One or more animal studies show brain and nervous system effects at high doses   BUTYLENE GLYCOL
One or more animal studies show brain and nervous system effects at moderate doses   PHENOXYETHANOL, CETEARETH-20, AMINOMETHYL PROPANOL,
One or more animal studies show any effects at moderate doses   CYCLOPENTASILOXANE
One or more animal studies show brain and nervous system effects at low doses   DISODIUM EDTA
One or more animal studies show brain and nervous system effects at very low doses   STEARIC ACID, FD&C YELLOW 5
Moderate evidence of human neurotoxicity   FRAGRANCE
Strong evidence of human neurotoxicity   MAGNESIUM ALUMINUM SILICATE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show endocrine system disruption at high doses   GLYCINE, GLYCERIN, DISODIUM EDTA, CHOLESTEROL, BUTYLENE GLYCOL
One or more animal studies show endocrine disruption at moderate doses   CYCLOPENTASILOXANE
One or more animal studies show endocrine disruption at moderate doses   ISOBUTYLPARABEN
Human any disruptor - moderate evidence   OXYBENZONE (BENZOPHENONE-3)
Human any disruptor - strong evidence   PROPYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), METHYLPARABEN, ETHYLPARABEN, BUTYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Limited evidence of skin and immune system toxicity   PHENOXYETHANOL
One or more human case studies show possible skin allergy effects   HYDROLYZED WHEAT PROTEIN, OCTINOXATE (OCTYL METHOXYCINNAMATE), OCTISALATE
Human immune system toxicant - moderate evidence   POLYETHYLENE
Human skin toxicant - strong evidence   TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN, ISOBUTYLPARABEN, ETHYLPARABEN, BUTYLPARABEN, ACETYLATED LANOLIN ALCOHOL
Possible human photoallergenic toxicant   OXYBENZONE (BENZOPHENONE-3)
Known human immune system toxicant   FRAGRANCE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Ingredient is suspected or measured to accumulate in people   OXYBENZONE (BENZOPHENONE-3)
Persistent, bioaccumulative in wildlife   CYCLOPENTASILOXANE
Ingredient is suspected or measured to accumulate in people   OCTINOXATE (OCTYL METHOXYCINNAMATE)
Persistent, bioaccumulative in wildlife   CHOLESTEROL

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)   OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)   CYCLOPENTASILOXANE, ACETYL GLUCOSAMINE, POLYSORBATE-20, STEARIC ACID, STEARYL ALCOHOL, FD&C YELLOW 6, PENTYLENE GLYCOL, GLYCINE, DICAPRYLYL MALEATE, BUTYLENE GLYCOL, AMINOMETHYL PROPANOL, CHOLESTEROL
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)   CETEARETH-20, PHENOXYETHANOL,
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)   OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)   TOCOPHERYL ACETATE, SODIUM DEHYDROACETATE, OCTISALATE, LINOLEIC ACID
Limited evidence of sense organ toxicity   PROPYLPARABEN, PEG/ PPG-20/ 15 DIMETHICONE, PEG-40 HYDROGENATED CASTOR OIL, ISOBUTYLPARABEN, ETHYLPARABEN, BUTYLPARABEN, MAGNESIUM ALUMINUM SILICATE
One or more animal studies show broad systemic effects at low doses   DISODIUM EDTA
One or more animal studies show musculoskeletal effects at very low doses   FD&C YELLOW 5, GLYCERIN
Known human any toxicant   METHYLPARABEN
Possible human immune system toxicant   POLYETHYLENE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Ingredient not fully labeled - identity unknown   FRAGRANCE

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Wildlife and environmental toxicity   OCTINOXATE (OCTYL METHOXYCINNAMATE), OXYBENZONE (BENZOPHENONE-3)
Wildlife and environmental toxicity   AMINOMETHYL PROPANOL, PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Not likely to be a skin irritant in humans   OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show skin irritation at high doses   PENTYLENE GLYCOL, CHOLESTEROL
One or more animal studies show skin irritation at moderate doses   POLYSORBATE-20, GLYCERIN, CYCLOPENTASILOXANE, CETYL ACETATE, BUTYLPARABEN
One or more animal studies show skin irritation at low doses   SYNTHETIC WAX, STEARIC ACID, SQUALANE, OCTISALATE, METHYLPARABEN, LINOLEIC ACID, CETEARETH-20
Human any irritant - strong evidence products for use around the eyes, on the skin, or may be aerosolized (airborne) BUTYLENE GLYCOL, POLYETHYLENE, STEARYL ALCOHOL
Classified as irritant   AMINOMETHYL PROPANOL, PHENOXYETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Safety assessment was based on related chemical   TRIUNDECANOIN, ISOBUTYLPARABEN
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   TOCOPHERYL ACETATE
Missing safety data noted by cosmetic industry review   POLYETHYLENE
Considered safe based on assumption of low absorption   POLYETHYLENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   SYNTHETIC WAX, STEARYL ALCOHOL, STEARIC ACID, SODIUM DEHYDROACETATE, PROPYLPARABEN, POLYSORBATE-20, PHENOXYETHANOL, POLYETHYLENE, OXYBENZONE (BENZOPHENONE-3), PEG/ PPG-20/ 15 DIMETHICONE, METHYLPARABEN, MAGNESIUM ALUMINUM SILICATE, DISODIUM EDTA, ETHYLPARABEN, DIMETHICONE, CHOLESTEROL, CERESIN, CARBOMER, BUTYLPARABEN, BUTYLENE GLYCOL, BEESWAX, ACETYLATED LANOLIN ALCOHOL
Not assessed for safety in cosmetics by industry panel   SCUTELLARIA BAICALENSIS EXTRACT, VITIS VINIFERA (GRAPE) FRUIT EXTRACT, SALVIA SCLAREA (CLARY SAGE) EXTRACT, SQUALANE, STEARATE, TOCOQUINONE, TRITICUM VULGARE (WHEAT) GERM EXTRACT, PORIA COCOS (FU-LING) EXTRACT, POLYDECENE, PHYTOSPHINGOSINE, PHENYL METHICONE, PENTYLENE GLYCOL, PENTAERYTHRITYL TETRAETHYLHEXANOATE, PALMITOYL PENTAPEPTIDE-3 (MATRIXYL), OCTISALATE, MORUS NIGRA (BLACK MULBERRY) ROOT EXTRACT, LINOLEIC ACID, HYDROLYZED WHEAT PROTEIN, HYDROGENATED VEGETABLE OIL, HORDEUM VULGARE (BARLEY) EXTRACT, DIETHYLHEXYL 2,6-NAPHTHALATE, FRAGRANCE, GLYCERIN, GLYCINE, GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT, DICAPRYLYL MALEATE, CYCLOPENTASILOXANE, CETYL ACETATE, CALLUNA VULGARIS (HEATHER) EXTRACT, BETULA ALBA (BIRCH) EXTRACT, ASCORBYL GLUCOSIDE, ALGAE EXTRACT, ACETYL GLUCOSAMINE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Allowed workplace exposures restricted to moderate doses   GLYCERIN
Allowed workplace exposures restricted to low doses   SYNTHETIC WAX,
Allowed workplace exposures restricted to low doses   SODIUM DEHYDROACETATE, PHENOXYETHANOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Does not produces excess reactive oxygen species or other harmful biochemical changes.   OCTISALATE
Interferes with gene expresion   BUTYLPARABEN, METHYLPARABEN
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood   POLYETHYLENE
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.   OXYBENZONE (BENZOPHENONE-3), OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood   GLYCINE, GLYCERIN, CYCLOPENTASILOXANE, CHOLESTEROL

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