MAC Underlacquer (2005 formulation) || Skin Deep: Cosmetic Safety Reviews

MAC UNDERLACQUER (2005 FORMULATION)

last updated: 04/01/05 brand: MAC by Estée Lauder

SCORE

moderate hazard (out of 10)

85%

data gap

BUY ONLINE/BETTER PRODUCTS

see online retailers

5% of nail polishs have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: ALCOHOL DENAT; ETHYL ACETATE; HEPTANE; BUTYL ACETATE; POLYVINYL BUTYRAL; TOSYLAMIDE/EPOXY RESIN; NITROCELLULOSE; ISOPROPYL ALCOHOL; ETHYL TOSYLAMIDE; TOCOPHERYL ACETATE; PANTHENOL; HYDROLYZED SOY PROTEIN; CALCIUM PANTOTHENATE; BENZOPHENONE-1; ASCORBIC ACID; RED 17 (CI 26100); YELLOW 5 LAKE (CI 19140)

user reviews & comments

NEW! No reviews or ratings yet. Log in and be the first to leave a comment!

ingredients

	score	data gap	concerns
BENZOPHENONE-1	5	79%	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ETHYL ACETATE	4	78%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
ALCOHOL DENATURED	5	71%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
D&C RED 17	2	70%	Persistence and bioaccumulation, Biochemical or cellular level changes
FD&C YELLOW 5 ALUMINUM LAKE YELLOW 5 LAKE	4	91%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
ISOPROPYL ALCOHOL	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PANTHENOL	2	88%	Multiple, additive exposure sources
HEPTANE	2	75%	Irritation (skin, eyes, or lungs), Occupational hazards
NITROCELLULOSE	1	94%	Organ system toxicity (non-reproductive)
ASCORBIC ACID (VITAMIN C)	1	91%	none identified
POLYVINYL BUTYRAL	0	89%	none identified
CALCIUM PANTOTHENATE	1	87%	none identified
BUTYL ACETATE	1	78%	Irritation (skin, eyes, or lungs), Occupational hazards
TOSYLAMIDE/ EPOXY RESIN	0	100%	none identified
ETHYL TOSYLAMIDE	0	94%	none identified
HYDROLYZED GLYCINE SOJA (SOY) PROTEIN HYDROLYZED SOY PROTEIN	0	94%	none identified

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		TOCOPHERYL ACETATE
One or more in vitro tests non-mammalian cells show positive mutation results		ETHYL ACETATE, ASCORBIC ACID (VITAMIN C)
One or more in vitro tests on mammalian cells show positive mutation results		ISOPROPYL ALCOHOL, D&C RED 17, ALCOHOL DENATURED
Cancer - not classifiable/not likely to be human carcinogen		HEPTANE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
One or more animal studies show reproductive effects at high doses		ALCOHOL DENATURED
Human nervous system toxicant - moderate evidence		FD&C YELLOW 5 ALUMINUM LAKE, ETHYL ACETATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		ETHYL ACETATE, BUTYL ACETATE
One or more animal studies show brain and nervous system effects at high doses		ISOPROPYL ALCOHOL, BENZOPHENONE-1
One or more animal studies show brain and nervous system effects at moderate doses		CALCIUM PANTOTHENATE
Strong evidence of human neurotoxicity		FD&C YELLOW 5 ALUMINUM LAKE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		HEPTANE, BENZOPHENONE-1, ALCOHOL DENATURED

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE, BENZOPHENONE-1

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		D&C RED 17

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		HEPTANE, ALCOHOL DENATURED, BENZOPHENONE-1, ISOPROPYL ALCOHOL, PANTHENOL, TOCOPHERYL ACETATE
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		D&C RED 17, CALCIUM PANTOTHENATE
Limited evidence of sense organ toxicity		ETHYL ACETATE, FD&C YELLOW 5 ALUMINUM LAKE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		TOCOPHERYL ACETATE, ISOPROPYL ALCOHOL, ETHYL ACETATE, CALCIUM PANTOTHENATE, BUTYL ACETATE, ASCORBIC ACID (VITAMIN C), ALCOHOL DENATURED
Used in food or as an additive with limited or no toxicity information available		PANTHENOL, ALCOHOL DENATURED

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		HEPTANE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		HEPTANE
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED, BUTYL ACETATE
One or more animal studies show skin irritation at moderate doses		ISOPROPYL ALCOHOL
Classified as irritant		ETHYL ACETATE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		ETHYL ACETATE, PANTHENOL, BUTYL ACETATE, BENZOPHENONE-1, ASCORBIC ACID (VITAMIN C)
Not assessed for safety in cosmetics by industry panel		POLYVINYL BUTYRAL, HEPTANE, TOSYLAMIDE/ EPOXY RESIN, NITROCELLULOSE, ISOPROPYL ALCOHOL, HYDROLYZED GLYCINE SOJA (SOY) PROTEIN, ETHYL TOSYLAMIDE, CALCIUM PANTOTHENATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHERYL ACETATE
Insufficient data to determine safety		HEPTANE, ALCOHOL DENATURED
Safety assessment was based on related chemical		ASCORBIC ACID (VITAMIN C)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED, BUTYL ACETATE, ETHYL ACETATE, ISOPROPYL ALCOHOL, HEPTANE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, D&C RED 17