Avon beComing PURE BRILLIANCE perfect balancing foundation with Lumin8TM, SPF 8 (2005 formulation) || Skin Deep: Cosmetic Safety Reviews

AVON BECOMING PURE BRILLIANCE PERFECT BALANCING FOUNDATION WITH LUMIN8TM, SPF 8 (2005 FORMULATION)

last updated: 04/01/05 brand: Avon by Avon Products, Inc.

SCORE

	health hazard
	sun hazard

83%

data gap

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95% of foundations have lower concerns
99% of sunscreen: makeups have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company does not test on animals.

Sunscreen effectiveness* breakdown

9	UVB hazard/exposure score
4	UVA hazard/exposure score
1	sunscreen instability

*Note that the same active ingredient combination may score differently in two different products depending on the concentration of the ingredients and the mixture of inactive ingredients.

Active ingredient UV
blocking strength

Product total

OCTINOXATE (OCTYL METHOXYCINNAMATE) ( 4.4? %)

TITANIUM DIOXIDE (NON-NANO) ( 3.6? %)

We have had to assume the percentage of the active ingredients in this product. If you own this product and it has the percentages printed on the package, you can help us fill in this missing information.

Note to manufacturers: We have assumed a typical particle size for the mineral(s) in your product based on typical industry use. We welcome specific data from manufacturers if actual particle size is different.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: ACTIVE INGREDIENTS :; OCTINOXATE; TITANIUM DIOXIDE; OTHER INGREDIENTS :; WATER; DIMETHICONE; PHENYL TRIMETHICONE; PROPYLENE GLYCOL; TALC; STEARYL DIMETHICONE; POLYMETHYL METHACRYLATE; HYDROGENATED POLYDECENE; GLYCERYL DILAURATE; ISOSTEARIC ACID; KAOLIN; TRIETHANOLAMINE; STEARETH 21; STEARIC ACID; CASTORYL MALEATE; MAGNESIUM ALUMINUM SILICATE; POLYPERFLUOROMETHYLISOPROPYL ETHER; IMIDAZOLIDINYL UREA; METHYLPARABEN; ALUMINUM HYDROXIDE; CELLULOSE GUM; STEARETH-2; PROPYLPARABEN; XANTHAN GUM; TETRASODIUM EDTA; ASCORBYL DIPALMITATE; FRAGRANCE; HYDROGENATED LECITHIN; HYDROXYPROPYLTRIMONIUM HYALURONATE; TOCOPHERYL ACETATE; RETINYL PALMITATE; LECITHIN; TRISODIUM HEDTA; C12-15 ALKYL BENZOATE; ETHYLENE/ACRYLIC ACID COPOLYMER; GLYCINE SOJA (SOYBEAN) SEED EXTRACT; HYALURONIC ACID; PANTHENOL; PHYTOL; CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT; BUTYLENE GLYCOL; TOCOPHEROL; PHENOXYETHANOL; HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT; ISOPROPYLPARABEN; PUNICA GRANATUM EXTRACT; VITIS VINIFERA (GRAPE) FRUIT EXTRACT; ASCORBYL PALMITATE; BETA-CAROTENE; HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL; MAY CONTAIN :; IRON OXIDES

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
OCTINOXATE (OCTYL METHOXYCINNAMATE) (Active Ingredient)	8	65%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
LECITHIN	3	70%	Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
TRIETHANOLAMINE	6	58%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
IMIDAZOLIDINYL UREA	5	70%	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
RETINYL PALMITATE	5	68%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
MAGNESIUM ALUMINUM SILICATE	4	88%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
ALUMINUM HYDROXIDE	4	86%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
TITANIUM DIOXIDE (NON-NANO) (Active Ingredient)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
TALC	3	86%	Organ system toxicity (non-reproductive), Contamination concerns (ASBESTIFORM FIBERS), Occupational hazards
ISOPROPYLPARABEN	3	84%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
DIMETHICONE	2	74%	Violations, restrictions & warnings
ETHYLENE/ ACRYLIC ACID COPOLYMER	3	74%	Organ system toxicity (non-reproductive), Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
HYDROGENATED POLYDECENE	2	94%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
PHYTOL	2	93%	Multiple, additive exposure sources, Irritation (skin, eyes, or lungs)
POLYMETHYL METHACRYLATE	1	89%	Organ system toxicity (non-reproductive)
PANTHENOL	2	88%	Multiple, additive exposure sources
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
IRON OXIDES	2	85%	Persistence and bioaccumulation, Enhanced skin absorption
BETA CAROTENE	1	84%	Organ system toxicity (non-reproductive)
TETRASODIUM EDTA	2	81%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
POLYPERFLUOROMETHYLISOPROPYL ETHER	2	80%	Persistence and bioaccumulation, Contamination concerns (PERFLUOROOCTANOIC ACID)
KAOLIN	1	79%	Occupational hazards
HYDROGENATED LECITHIN	2	74%	Enhanced skin absorption, Contamination concerns (NITROSAMINES)
STEARIC ACID	2	74%	Neurotoxicity, Irritation (skin, eyes, or lungs)
C12-15 ALKYL BENZOATE	0	94%	none identified
ISOSTEARIC ACID	0	93%	none identified
PHENYL TRIMETHICONE	0	93%	none identified
STEARETH-21	1	89%	none identified
ASCORBYL PALMITATE (VITAMIN C PALMITATE)	1	88%	none identified
STEARETH-2	1	88%	none identified
CELLULOSE GUM	1	80%	none identified
BUTYLENE GLYCOL	1	79%	Irritation (skin, eyes, or lungs)
GLYCERYL DILAURATE	1	74%	none identified
CASTORYL MALEATE	0	100%	none identified
CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT	0	100%	none identified
GLYCINE SOJA (SOYBEAN) SEED EXTRACT	0	100%	none identified
HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT	0	100%	none identified
HYDROXYPROPYLTRIMONIUM HYALURONATE	0	100%	none identified
VITIS VINIFERA (GRAPE) FRUIT EXTRACT	0	100%	none identified
PUNICA GRANATUM (POMEGRANATE) EXTRACT PUNICA GRANATUM EXTRACT	0	100%	none identified
ASCORBYL DIPALMITATE	0	99%	none identified
STEARYL DIMETHICONE	0	99%	none identified
HELIANTHUS ANNUUS (SUNFLOWER) OIL HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL	0	94%	none identified
HYALURONIC ACID	0	94%	none identified
XANTHAN GUM	0	94%	none identified
TRISODIUM HEDTA	0	90%	Enhanced skin absorption
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show tumor formation at high doses		CELLULOSE GUM
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHERYL ACETATE, TOCOPHEROL, TITANIUM DIOXIDE (NON-NANO), PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN
Cancer - limited evidence		RETINYL PALMITATE
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - not classifiable/not likely to be human carcinogen		TRIETHANOLAMINE, POLYMETHYL METHACRYLATE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		KAOLIN, BUTYLENE GLYCOL
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, CELLULOSE GUM, BETA CAROTENE
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE,
One or more animal studies show any effects at low doses		PROPYLPARABEN
Human nervous system toxicant - moderate evidence		MAGNESIUM ALUMINUM SILICATE, ALUMINUM HYDROXIDE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		GLYCERYL DILAURATE, HYDROGENATED LECITHIN, PROPYLENE GLYCOL, TRIETHANOLAMINE, ETHYLENE/ ACRYLIC ACID COPOLYMER, LECITHIN
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		RETINYL PALMITATE, PHENOXYETHANOL
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		ALUMINUM HYDROXIDE, MAGNESIUM ALUMINUM SILICATE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		STEARIC ACID
One or more animal studies show brain and nervous system effects at high doses		RETINYL PALMITATE, PROPYLENE GLYCOL
One or more animal studies show brain and nervous system effects at moderate doses		KAOLIN, LECITHIN, METHYLPARABEN, PHENOXYETHANOL
One or more animal studies show brain and nervous system effects at high doses		BUTYLENE GLYCOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		TRIETHANOLAMINE
One or more studies show weak endocrine disruption		ISOPROPYLPARABEN
One or more animal studies show endocrine system disruption at high doses		BUTYLENE GLYCOL
Human any disruptor - strong evidence		PROPYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human skin toxicant - strong evidence		PROPYLPARABEN, TOCOPHERYL ACETATE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		METHYLPARABEN, ISOPROPYLPARABEN
Known human immune system toxicant		TRIETHANOLAMINE, IMIDAZOLIDINYL UREA, FRAGRANCE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		TITANIUM DIOXIDE (NON-NANO), TRIETHANOLAMINE, TALC, POLYMETHYL METHACRYLATE, HYDROGENATED POLYDECENE, ETHYLENE/ ACRYLIC ACID COPOLYMER, ALUMINUM HYDROXIDE
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Persistent, bioaccumulative in wildlife and humans		IRON OXIDES, POLYPERFLUOROMETHYLISOPROPYL ETHER

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		ASCORBYL PALMITATE (VITAMIN C PALMITATE), CELLULOSE GUM
Classified as expected to be toxic or harmful		TALC, POLYMETHYL METHACRYLATE, HYDROGENATED POLYDECENE, ETHYLENE/ ACRYLIC ACID COPOLYMER
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient)		IMIDAZOLIDINYL UREA, STEARIC ACID, PANTHENOL
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	PROPYLENE GLYCOL, BUTYLENE GLYCOL
Limited evidence of sense organ toxicity		PROPYLPARABEN, RETINYL PALMITATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		TOCOPHERYL ACETATE, STEARETH-2, STEARETH-21
Limited evidence of sense organ toxicity		ISOPROPYLPARABEN, MAGNESIUM ALUMINUM SILICATE
One or more animal studies show cardiovascular effects at low doses		BETA CAROTENE, ALUMINUM HYDROXIDE
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	PHENOXYETHANOL
One or more animal studies show cardiovascular effects at very low doses		TITANIUM DIOXIDE (NON-NANO)
Limited evidence of eye toxicity	products for use around the eyes	TETRASODIUM EDTA
Possible human immune system toxicant		TRIETHANOLAMINE
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		TITANIUM DIOXIDE (NON-NANO), TRIETHANOLAMINE, XANTHAN GUM, TOCOPHERYL ACETATE, TOCOPHEROL, TETRASODIUM EDTA, TALC, IRON OXIDES, STEARIC ACID, RETINYL PALMITATE, PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN, LECITHIN, DIMETHICONE, CELLULOSE GUM, BUTYLENE GLYCOL, BETA CAROTENE, ASCORBYL PALMITATE (VITAMIN C PALMITATE), ALUMINUM HYDROXIDE
Used in food or as an additive with limited or no toxicity information available		PHYTOL, PANTHENOL, LECITHIN

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		HYDROGENATED POLYDECENE
Not suspected to be an environmental toxin		TITANIUM DIOXIDE (NON-NANO), TRIETHANOLAMINE, TALC, POLYMETHYL METHACRYLATE, ETHYLENE/ ACRYLIC ACID COPOLYMER, ALUMINUM HYDROXIDE
Wildlife and environmental toxicity		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		TITANIUM DIOXIDE (NON-NANO), TALC
One or more animal studies show skin irritation at low doses		TETRASODIUM EDTA, STEARIC ACID, PHYTOL, METHYLPARABEN
One or more animal studies show skin irritation at very low doses		TRIETHANOLAMINE
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL
Classified as skin irritant		PROPYLENE GLYCOL, PHENOXYETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		STEARETH-2, STEARYL DIMETHICONE, PROPYLENE GLYCOL, GLYCERYL DILAURATE
Missing safety data noted by cosmetic industry review		ISOSTEARIC ACID
Safety assessment was based on related chemical		ISOPROPYLPARABEN, ASCORBYL DIPALMITATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TRISODIUM HEDTA
Considered safe based on assumption of low absorption		ETHYLENE/ ACRYLIC ACID COPOLYMER, GLYCERYL DILAURATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		STEARETH-2
Missing safety data noted by cosmetic industry review		GLYCERYL DILAURATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TETRASODIUM EDTA, TOCOPHERYL ACETATE, TOCOPHEROL, STEARIC ACID, RETINYL PALMITATE, PHENYL TRIMETHICONE, PROPYLPARABEN, PANTHENOL, PHENOXYETHANOL, METHYLPARABEN, MAGNESIUM ALUMINUM SILICATE, ISOSTEARIC ACID, DIMETHICONE, IMIDAZOLIDINYL UREA, CELLULOSE GUM, BUTYLENE GLYCOL
Not assessed for safety in cosmetics by industry panel		TITANIUM DIOXIDE (NON-NANO), VITIS VINIFERA (GRAPE) FRUIT EXTRACT, XANTHAN GUM, PUNICA GRANATUM (POMEGRANATE) EXTRACT, STEARETH-21
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		ASCORBYL PALMITATE (VITAMIN C PALMITATE)
Not assessed for safety in cosmetics by industry panel		TALC, POLYPERFLUOROMETHYLISOPROPYL ETHER, POLYMETHYL METHACRYLATE, PHYTOL, HYDROXYPROPYLTRIMONIUM HYALURONATE, HYDROGENATED POLYDECENE, HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT, HELIANTHUS ANNUUS (SUNFLOWER) OIL, GLYCINE SOJA (SOYBEAN) SEED EXTRACT, FRAGRANCE, CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT, CASTORYL MALEATE, C12-15 ALKYL BENZOATE, BETA CAROTENE, ALUMINUM HYDROXIDE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), PHENOXYETHANOL, TETRASODIUM EDTA
Allowed workplace exposures restricted to moderate doses		TRIETHANOLAMINE
Allowed workplace exposures restricted to low doses		KAOLIN, TALC

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		METHYLPARABEN
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		BETA CAROTENE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CELLULOSE GUM, PROPYLENE GLYCOL