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35% of anti-agings have lower concerns
41% of facial moisturizer/treatments have lower concerns




Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: WATER, GLYCOLIC ACID (ALPHA HYDROXY ACID), ARGININE, GLYCERIN, ALCOHOL DENAT, HYDROXYETHYLCELLULOSE, SALICYLIC ACID (BETA HYDROXY ACID), DMDM HYDANTOIN, AMMONIUM HYDROXIDE
Directions from packaging: Skin should be clean and free of irritation. Apply a very thin layer to clean non-irritated skin every other night for two weeks. After two weeks, apply a very thin layer to clean skin every night. After one month of use, you may apply a very thin layer to clean, non-irritated skin all day and all night. Allow ten minutes for the product to absorb, and follow, if needed, with prescribed PeterThomasRoth treatment products at night and prescribed moisturizer and oil-free sun care products during the day.
Warnings from packaging: For external use only. Keep out of reach of children. Avoid contact with eyes and mucous membranes. Some initial stinging may occur in sensitive individuals. This product may cause irritation. Thick applications are responsible for most irritation. Reduce irritation by always applying the product in a very thin layer and if needed, less frequently. If irritation continues, temporarily discontinue use and consult your skin care specialist.
| score | data gap | concerns | |
| DMDM HYDANTOIN | 7 | 71% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE) |
| ALCOHOL DENATURED | 5 | 71% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| GLYCOLIC ACID | 4 | 70% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive) |
| ARGININE | 3 | 79% | Neurotoxicity, Organ system toxicity (non-reproductive) |
| AMMONIUM HYDROXIDE | 2 | 81% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| HYDROXYETHYLCELLULOSE | 1 | 82% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | AMMONIUM HYDROXIDE | |
| One or more in vitro tests on mammalian cells show positive mutation results | GLYCERIN, ARGININE | |
| Cancer - limited evidence | ALCOHOL DENATURED |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | HYDROXYETHYLCELLULOSE, GLYCOLIC ACID | |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN, ARGININE | |
| Limited evidence of reproductive toxicity | ALCOHOL DENATURED |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | GLYCOLIC ACID | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | DMDM HYDANTOIN, GLYCOLIC ACID, DMDM HYDANTOIN | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits | GLYCOLIC ACID |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | GLYCERIN, HYDROXYETHYLCELLULOSE | |
| One or more animal studies show brain and nervous system effects at very low doses | ARGININE | |
| One or more animal studies show brain and nervous system effects at moderate doses | GLYCOLIC ACID |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | ALCOHOL DENATURED, GLYCERIN | |
| One or more animal studies show endocrine disruption at moderate doses | ARGININE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | DMDM HYDANTOIN |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | ALCOHOL DENATURED, AMMONIUM HYDROXIDE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | GLYCOLIC ACID |
| One or more animal studies show cardiovascular effects at high doses (low dose studies may be unavailable for this ingredient) | HYDROXYETHYLCELLULOSE | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | DMDM HYDANTOIN | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | AMMONIUM HYDROXIDE |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | ALCOHOL DENATURED |
| One or more animal studies show cardiovascular effects at very low doses | ARGININE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | GLYCERIN, ARGININE, AMMONIUM HYDROXIDE, ALCOHOL DENATURED | |
| Used in food or as an additive with limited or no toxicity information available | ALCOHOL DENATURED |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | ALCOHOL DENATURED | |
| Wildlife and environmental toxicity | AMMONIUM HYDROXIDE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | GLYCERIN | |
| One or more animal studies show skin irritation at low doses | ALCOHOL DENATURED | |
| Human skin irritant - moderate evidence | AMMONIUM HYDROXIDE | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | DMDM HYDANTOIN |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not assessed for safety in cosmetics by industry panel | GLYCERIN | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DMDM HYDANTOIN | |
| Insufficient data to determine safety | ALCOHOL DENATURED | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | HYDROXYETHYLCELLULOSE | |
| Not assessed for safety in cosmetics by industry panel | ARGININE, AMMONIUM HYDROXIDE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ALCOHOL DENATURED | |
| No workplace limits set | GLYCOLIC ACID | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | ALCOHOL DENATURED, ARGININE, GLYCERIN |
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