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PETER THOMAS ROTH GLYCOLIC ACID 10% CLARIFYING GEL (2005 FORMULATION)

last updated: 04/01/05 brand: Peter Thomas Roth by Peter Thomas Roth Labs

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.


Ingredients in this product are linked to:
yesCancer
yesDevelopmental/reproductive toxicity
yesViolations, restrictions & warnings
yesAllergies/immunotoxicity
yesOther concerns for ingredients used in this product:
Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards


Ingredients from packaging: WATER, GLYCOLIC ACID (ALPHA HYDROXY ACID), ARGININE, GLYCERIN, ALCOHOL DENAT, HYDROXYETHYLCELLULOSE, SALICYLIC ACID (BETA HYDROXY ACID), DMDM HYDANTOIN, AMMONIUM HYDROXIDE

Directions from packaging: Skin should be clean and free of irritation. Apply a very thin layer to clean non-irritated skin every other night for two weeks. After two weeks, apply a very thin layer to clean skin every night. After one month of use, you may apply a very thin layer to clean, non-irritated skin all day and all night. Allow ten minutes for the product to absorb, and follow, if needed, with prescribed PeterThomasRoth treatment products at night and prescribed moisturizer and oil-free sun care products during the day.

Warnings from packaging: For external use only. Keep out of reach of children. Avoid contact with eyes and mucous membranes. Some initial stinging may occur in sensitive individuals. This product may cause irritation. Thick applications are responsible for most irritation. Reduce irritation by always applying the product in a very thin layer and if needed, less frequently. If irritation continues, temporarily discontinue use and consult your skin care specialist.

 

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ingredients

     score    data gap       concerns
DMDM HYDANTOIN771%Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
ALCOHOL DENATURED571%Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
GLYCOLIC ACID470%Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
ARGININE379%Neurotoxicity, Organ system toxicity (non-reproductive)
AMMONIUM HYDROXIDE281%Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
GLYCERIN274%Organ system toxicity (non-reproductive), Occupational hazards
HYDROXYETHYLCELLULOSE182%none identified
WATER00%innocuous


Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results   AMMONIUM HYDROXIDE
One or more in vitro tests on mammalian cells show positive mutation results   GLYCERIN, ARGININE
Cancer - limited evidence   ALCOHOL DENATURED

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show reproductive effects at high doses   HYDROXYETHYLCELLULOSE, GLYCOLIC ACID
One or more animal studies show reproductive effects at moderate doses   GLYCERIN, ARGININE
Limited evidence of reproductive toxicity   ALCOHOL DENATURED

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications   GLYCOLIC ACID
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)   DMDM HYDANTOIN, GLYCOLIC ACID, DMDM HYDANTOIN
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits   GLYCOLIC ACID

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show brain and nervous system effects at high doses   GLYCERIN, HYDROXYETHYLCELLULOSE
One or more animal studies show brain and nervous system effects at very low doses   ARGININE
One or more animal studies show brain and nervous system effects at moderate doses   GLYCOLIC ACID

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show endocrine system disruption at high doses   ALCOHOL DENATURED, GLYCERIN
One or more animal studies show endocrine disruption at moderate doses   ARGININE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Known human immune system toxicant   DMDM HYDANTOIN

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Not suspected to be bioaccumulative   ALCOHOL DENATURED, AMMONIUM HYDROXIDE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show sense organ effects at very low doses products for use around the eyes, mouth, or lips GLYCOLIC ACID
One or more animal studies show cardiovascular effects at high doses (low dose studies may be unavailable for this ingredient)   HYDROXYETHYLCELLULOSE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)   DMDM HYDANTOIN
One or more animal studies show sense organ effects at very low doses products for use around the eyes, mouth, or lips AMMONIUM HYDROXIDE
One or more animal studies show kidney or renal system effects at very low doses   GLYCERIN,
One or more animal studies show sense organ effects at very low doses products for use around the eyes, mouth, or lips ALCOHOL DENATURED
One or more animal studies show cardiovascular effects at very low doses   ARGININE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Designated as safe for general or specific, limited use in food   GLYCERIN, ARGININE, AMMONIUM HYDROXIDE, ALCOHOL DENATURED
Used in food or as an additive with limited or no toxicity information available   ALCOHOL DENATURED

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Not suspected to be an environmental toxin   ALCOHOL DENATURED
Wildlife and environmental toxicity   AMMONIUM HYDROXIDE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show skin irritation at moderate doses   GLYCERIN
One or more animal studies show skin irritation at low doses   ALCOHOL DENATURED
Human skin irritant - moderate evidence   AMMONIUM HYDROXIDE
Human any irritant - strong evidence products for use around the eyes, on the skin, or may be aerosolized (airborne) DMDM HYDANTOIN

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Not assessed for safety in cosmetics by industry panel   GLYCERIN
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   DMDM HYDANTOIN
Insufficient data to determine safety   ALCOHOL DENATURED
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   HYDROXYETHYLCELLULOSE
Not assessed for safety in cosmetics by industry panel   ARGININE, AMMONIUM HYDROXIDE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Allowed workplace exposures restricted to high doses   ALCOHOL DENATURED
No workplace limits set   GLYCOLIC ACID
Allowed workplace exposures restricted to moderate doses   GLYCERIN

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood   ALCOHOL DENATURED, ARGININE, GLYCERIN

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