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Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards |
Ingredients from packaging: ACTIVE INGREDIENTS: CONTAINS: COAL TAR TOPICAL SOLUTION USP, 5 (EQUIVALENT TO 1 W/V COAL TAR). INACTIVE INGREDIENTS: WATER, LAURETH-23, ALCOHOL 12 (V/V), LAURETH-4, ISOPROPYL ALCOHOL 4 (V/V), BENZALKONIUM CHLORIDE, TETRASODIUM EDTA, MAY CONTAIN CITRIC ACID AND/OR SODIUM HYDROXIDE TO ADJUST PH. DIRECTIONS: MASSAGE IONIL T SHAMPOO INTO WET HAIR. DON'T EXPECT AS MUCH INITIAL SUDSING AS WITH NON-MEDICATED SHAMPOOS. RINSE, THEN APPLY IONIL T AGAIN AND MASSAGE INTO A LATHER. ALLOW TO REMAIN IN HAIR FOR ABOUT 5 MINUTES BEFORE RINSING. FOR BEST RESULTS, USE AT LEAST TWICE A WEEK OR AS DIRECTED BY A PHYSICIAN. DO NOT USE SOAP, DETERGENT OR OTHER SHAMPOO ON HAIR BEFORE OR AFTER USING IONIL T. A COMPATIBLE AFTER-SHAMPOO CONDITIONER IS IONIL RINSE.
Directions from packaging: Massage Ionil T Shampoo into wet hair. Don't expect as much initial sudsing as with non-medicated shampoos. Rinse, then apply Ionil T again and massage into a lather. Allow to remain in hair for about 5 minutes before rinsing. For best results, use at least twice a week or as directed by a physician. Do not use soap, detergent or other shampoo on hair before or after using Ionil T. A compatible after-shampoo conditioner is Ionil Rinse.
Warnings from packaging: For external use only. Avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water. If condition worsens or does not improve after regular use of this product as directed, consult a physician. If condition covers a large area of the body, consult your physician before using this product. Use caution in exposing skin to sunlight after applying this product. It may increase your tendency to sunburn for up to 24 hours after application. Do not use this product with other forms of psoriasis therapy such as ultraviolet radiation or prescription drugs unless directed to do so by a physician. Do not use for prolonged periods without consulting a physician. Keep this and all drugs out of the reach of children. In case of accidental ingestion, seek professional assistance, or contact a poison control center immediately.
| score | data gap | concerns | |
| COAL TAR (USP) | 10 | 57% | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (BENZO[A]PYRENE) |
| BENZALKONIUM CHLORIDE | 7 | 62% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| LAURETH-23 | 5 | 83% | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| ALCOHOL DENATURED ALCOHOL 12 (V/V) | 5 | 71% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| LAURETH-4 | 3 | 96% | Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| SODIUM HYDROXIDE | 3 | 77% | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| CITRIC ACID | 2 | 72% | Violations, restrictions & warnings |
| TETRASODIUM EDTA | 2 | 81% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | LAURETH-23 | |
| Cancer - limited evidence | ALCOHOL DENATURED | |
| One or more in vitro tests on mammalian cells show positive mutation results | BENZALKONIUM CHLORIDE, SODIUM HYDROXIDE | |
| Cancer - not classifiable/not likely to be human carcinogen | ISOPROPYL ALCOHOL | |
| Known human carcinogen | COAL TAR |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of reproductive toxicity | ALCOHOL DENATURED, ISOPROPYL ALCOHOL |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | BENZALKONIUM CHLORIDE, CITRIC ACID | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | COAL TAR | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | BENZALKONIUM CHLORIDE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | BENZALKONIUM CHLORIDE | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | COAL TAR, COAL TAR |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at low doses | LAURETH-23 | |
| One or more animal studies show brain and nervous system effects at very low doses | SODIUM HYDROXIDE | |
| Strong evidence of human neurotoxicity | ISOPROPYL ALCOHOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | ALCOHOL DENATURED |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin toxicant - strong evidence | COAL TAR | |
| Known human immune system toxicant | BENZALKONIUM CHLORIDE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | SODIUM HYDROXIDE, ISOPROPYL ALCOHOL, COAL TAR | |
| Not suspected to be persistent | LAURETH-23 | |
| Not suspected to be bioaccumulative | ALCOHOL DENATURED |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show kidney or renal system effects at moderate doses (low dose studies may be unavailable for this ingredient) | TETRASODIUM EDTA, CITRIC ACID | |
| Limited evidence of sense organ toxicity | ISOPROPYL ALCOHOL, ALCOHOL DENATURED | |
| One or more animal studies show broad systemic effects at low doses | LAURETH-23 | |
| One or more animal studies show metabolic effects at very low doses | SODIUM HYDROXIDE | |
| Possible human immune system toxicant | BENZALKONIUM CHLORIDE | |
| Known human respiratory toxicant | COAL TAR |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TETRASODIUM EDTA, ISOPROPYL ALCOHOL, LAURETH-23, SODIUM HYDROXIDE, CITRIC ACID, ALCOHOL DENATURED | |
| Used in food or as an additive with limited or no toxicity information available | ALCOHOL DENATURED |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | LAURETH-23, COAL TAR | |
| Not suspected to be an environmental toxin | SODIUM HYDROXIDE, ISOPROPYL ALCOHOL, ALCOHOL DENATURED |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | COAL TAR, CITRIC ACID | |
| One or more animal studies show skin irritation at low doses | BENZALKONIUM CHLORIDE, TETRASODIUM EDTA | |
| One or more animal studies show skin irritation at very low doses | SODIUM HYDROXIDE | |
| One or more animal studies show skin irritation at low doses | ALCOHOL DENATURED | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | LAURETH-4, LAURETH-23 |
| Classified as irritant | ISOPROPYL ALCOHOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | LAURETH-4 | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | LAURETH-4 | |
| Insufficient data to determine safety | COAL TAR | |
| Safety assessment was based on related chemical | LAURETH-23 | |
| Insufficient data to determine safety | ALCOHOL DENATURED | |
| Missing safety data noted by cosmetic industry review | COAL TAR | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TETRASODIUM EDTA, LAURETH-23 | |
| Not assessed for safety in cosmetics by industry panel | SODIUM HYDROXIDE, ISOPROPYL ALCOHOL, CITRIC ACID |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | TETRASODIUM EDTA | |
| No workplace limits set | SODIUM HYDROXIDE | |
| Allowed workplace exposures restricted to high doses | ALCOHOL DENATURED | |
| Allowed workplace exposures restricted to high doses | ISOPROPYL ALCOHOL |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CITRIC ACID, ALCOHOL DENATURED | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | LAURETH-23 |
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