

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
Ingredients from packaging: WATER (AQUA), CYCLOPENTASILOXANE, STEARYL ALCOHOL, DIMETHICONE, CETYL ALCOHOL, PANTHENOL, PANTHENYL ETHYL ETHER, STEARAMIDOPROPYL ALCOHOL, TETRASODIUM EDTA, CITRIC ACID, METHYLCHLOROISOTHIAZOLINONE/METHYLISOTHIAZOLINONE, FRAGRANCE (PARFUM)
Directions from packaging: After shampooing with Wet Your Appetite Nourishing Shampoo, massage a generous amount into hair, working through to ends. Rinse completely and follow with your styling Binge.
| score | data gap | concerns | |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| METHYLCHLOROISOTHIAZOLINONE | 6 | 63% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| CYCLOPENTASILOXANE | 2 | 79% | Persistence and bioaccumulation |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| CITRIC ACID | 2 | 72% | Violations, restrictions & warnings |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| TETRASODIUM EDTA | 2 | 81% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| CETYL ALCOHOL | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| STEARYL ALCOHOL | 1 | 84% | Irritation (skin, eyes, or lungs) |
| PANTHENYL ETHYL ETHER | 0 | 100% | none identified |
| STEARAMIDOPROPYL ALCOHOL | 0 | 100% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | STEARYL ALCOHOL | |
| One or more in vitro tests non-mammalian cells show positive mutation results | METHYLCHLOROISOTHIAZOLINONE | |
| One or more animal studies show tumor formation at moderate doses | CYCLOPENTASILOXANE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | METHYLCHLOROISOTHIAZOLINONE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | METHYLCHLOROISOTHIAZOLINONE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - concentration limit in some types of cosmetics when combined with certain other ingredient(s) | METHYLCHLOROISOTHIAZOLINONE, CITRIC ACID, METHYLCHLOROISOTHIAZOLINONE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show any effects at moderate doses | CYCLOPENTASILOXANE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine disruption at moderate doses | CYCLOPENTASILOXANE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | METHYLCHLOROISOTHIAZOLINONE, FRAGRANCE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be persistent | CETYL ALCOHOL | |
| Persistent, bioaccumulative in wildlife | CYCLOPENTASILOXANE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | CYCLOPENTASILOXANE, CETYL ALCOHOL, STEARYL ALCOHOL, PANTHENOL | |
| One or more animal studies show kidney or renal system effects at moderate doses (low dose studies may be unavailable for this ingredient) | TETRASODIUM EDTA, CITRIC ACID | |
| Possible human immune system toxicant | METHYLCHLOROISOTHIAZOLINONE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TETRASODIUM EDTA, STEARYL ALCOHOL, DIMETHICONE, CITRIC ACID, CETYL ALCOHOL | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | CETYL ALCOHOL |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | CYCLOPENTASILOXANE, CITRIC ACID | |
| One or more animal studies show skin irritation at low doses | TETRASODIUM EDTA | |
| One or more animal studies show skin irritation at very low doses | CETYL ALCOHOL | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | STEARYL ALCOHOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | STEARYL ALCOHOL, TETRASODIUM EDTA, DIMETHICONE, PANTHENOL, CETYL ALCOHOL | |
| Not assessed for safety in cosmetics by industry panel | STEARAMIDOPROPYL ALCOHOL, PANTHENYL ETHYL ETHER, FRAGRANCE, CYCLOPENTASILOXANE, CITRIC ACID |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | TETRASODIUM EDTA |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CITRIC ACID, CYCLOPENTASILOXANE |
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