Reviva Reviva Placenta Ampules || Skin Deep: Cosmetic Safety Reviews

REVIVA REVIVA PLACENTA AMPULES

last updated: 04/01/05 brand: Reviva by Reviva Labs, Inc.

SCORE

moderate hazard (out of 10)

73%

data gap

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34% of facial moisturizer/treatments have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-compliant: This company has signed the Compact for Safe Cosmetics but is not in compliance because of their use of one or more ingredients prohibited or restricted under the Compact.

Animal Testing Policy
This company does not test on animals.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Endocrine disruption, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: ORANGE FLOWER WATER, PLACENTAL EXTRACT, "LYOPHILIZED BEEF PLACENTA", GLYCERIN, POLYSORBATE 20, CAPRYLIC/CAPRIC GLYCERIDES, METHYL & PROPYL PARABEN, DIAZOLIDINYL UREA, STABILIZED BETA CAROTENE.

Directions from packaging: Shake well before use. Use on well-cleansed skin. Remember, too, that a once-a-week use of Reviva Light Skin Peel is an important cleansing supplement and will aid absorption of ampules. Shake vial before use. Break off top with tissue wrapped around neck of ampule. Pour into palm and pat or massage lightly onto face and throat. Use for seven consecutive nights. A single ampule is generally used over two nights - just put foil on end of ampule and refrigerate.

Warnings from packaging: External use only.

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
DIAZOLIDINYL UREA	6	59%	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
PLACENTAL EXTRACT	5	75%	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (PROGESTERONE, ESTROGEN, ESTRONE)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
LYOPHILIZED BEEF PLACENTA	4	96%	Organ system toxicity (non-reproductive), Contamination concerns (PROGESTERONE, ESTROGEN, ESTRONE)
BETA CAROTENE	1	84%	Organ system toxicity (non-reproductive)
GLYCERIN	2	74%	Organ system toxicity (non-reproductive), Occupational hazards
CAPRYLIC/ CAPRIC GLYCERIDES	0	94%	none identified
POLYSORBATE-20	1	84%	none identified
CITRUS AURANTIUM DULCIS (ORANGE) FLOWER WATER	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		PROPYLPARABEN, METHYLPARABEN, GLYCERIN, DIAZOLIDINYL UREA

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		POLYSORBATE-20
One or more animal studies show reproductive effects at moderate doses		GLYCERIN, BETA CAROTENE
One or more animal studies show any effects at low doses		PROPYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		DIAZOLIDINYL UREA
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		PLACENTAL EXTRACT
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN, DIAZOLIDINYL UREA
One or more animal studies show brain and nervous system effects at moderate doses		METHYLPARABEN

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		GLYCERIN, DIAZOLIDINYL UREA
One or more studies show weak endocrine disruption		PLACENTAL EXTRACT, LYOPHILIZED BEEF PLACENTA
Human any disruptor - strong evidence		PROPYLPARABEN, METHYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human skin toxicant - strong evidence		PROPYLPARABEN, METHYLPARABEN
Known human immune system toxicant		DIAZOLIDINYL UREA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient)		POLYSORBATE-20, DIAZOLIDINYL UREA
Limited evidence of sense organ toxicity		PROPYLPARABEN
Potential risk of infectious disease - any		LYOPHILIZED BEEF PLACENTA
One or more animal studies show cardiovascular effects at low doses		BETA CAROTENE
Potential risk of infectious disease - any		PLACENTAL EXTRACT
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN
Known human any toxicant		METHYLPARABEN

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		POLYSORBATE-20, GLYCERIN
One or more animal studies show skin irritation at low doses		METHYLPARABEN

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PROPYLPARABEN
Insufficient data to determine safety		PLACENTAL EXTRACT
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		POLYSORBATE-20, METHYLPARABEN
Not assessed for safety in cosmetics by industry panel		CITRUS AURANTIUM DULCIS (ORANGE) FLOWER WATER, LYOPHILIZED BEEF PLACENTA, GLYCERIN, CAPRYLIC/ CAPRIC GLYCERIDES, BETA CAROTENE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		GLYCERIN

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		GLYCERIN
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		BETA CAROTENE
Interferes with gene expresion		METHYLPARABEN