

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
Ingredients from packaging: ACTIVE INGREDIENTS: ALUMINUM ZIRCONIUM TETRACHLOROHYDREX. OTHER INGREDIENTS: WATER, DIPROPYLENE GLYCOL, CYCLOMETHICONE, DIMETHICONE, GLYCERIN, DIMETHICONE COPOLYOL.
Directions from packaging: Remove protective seal and slowly turn dial to release a small amount of gel. Smooth thin layer onto underarms. Replace cap tightly.
Warnings from packaging: Do not use if skin is broken or irritated. As with all anti-perspirants, discontinue use if rash develops.
| score | data gap | concerns | |
| ALUMINUM ZIRCONIUM TETRACHLOROHYDREX (Active Ingredient) | 0 | 91% | none identified |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| CYCLOMETHICONE | 2 | 83% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| DIPROPYLENE GLYCOL | 1 | 84% | Irritation (skin, eyes, or lungs) |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | GLYCERIN |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | DIPROPYLENE GLYCOL, GLYCERIN |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | GLYCERIN |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Persistent, bioaccumulative in wildlife | CYCLOMETHICONE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | CYCLOMETHICONE | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN | |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | DIPROPYLENE GLYCOL |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Suspected to be an environmental toxin | CYCLOMETHICONE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | DIPROPYLENE GLYCOL |
| One or more animal studies show skin irritation at moderate doses | CYCLOMETHICONE, GLYCERIN |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DIPROPYLENE GLYCOL, DIMETHICONE | |
| Not assessed for safety in cosmetics by industry panel | GLYCERIN | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | CYCLOMETHICONE | |
| Not assessed for safety in cosmetics by industry panel | ALUMINUM ZIRCONIUM TETRACHLOROHYDREX |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CYCLOMETHICONE, GLYCERIN |
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