

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: BUTYL ACETATE, ETHYL ACETATE, NITROCELLULOSE, FORMALDEHYDE RESIN, ISOPROPYL ALCOHOL, DIBUTYL PHTHALATE, BUTYL ALCOHOL, SILICA, YOLUSIN ESULSONANIDE, BENZOPHENONE-1, CALCIUM PANTOTHENATE, CALCIUM CARBONATE, PROTEIN.
Directions from packaging: To protect and seal your manicure, apply one or two coats over dry polish. As a clear polish, wear one or two coats to protect and seal your nails. For continued therapeutic results, apply a fresh coat every third day.
Warnings from packaging: Do not heat or use near flame.
| score | data gap | concerns | |
| DIBUTYL PHTHALATE | 10 | 49% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards |
| SILICA | 1 | 69% | Biochemical or cellular level changes |
| BENZOPHENONE-1 | 5 | 79% | Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| ETHYL ACETATE | 4 | 78% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| BUTYL ALCOHOL | 5 | 61% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| ISOPROPYL ALCOHOL | 4 | 72% | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| NITROCELLULOSE | 1 | 94% | Organ system toxicity (non-reproductive) |
| CALCIUM CARBONATE | 1 | 87% | Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| CALCIUM PANTOTHENATE | 1 | 87% | none identified |
| BUTYL ACETATE | 1 | 78% | Irritation (skin, eyes, or lungs), Occupational hazards |
| FORMALDEHYDE RESIN | 0 | 100% | none identified |
| PROTEIN | 0 | 100% | none identified |
| YOLUSIN ESULSONANIDE | 0 | 100% | none identified |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | ETHYL ACETATE | |
| Cancer - not classifiable/not likely to be human carcinogen | BUTYL ALCOHOL, DIBUTYL PHTHALATE | |
| Cancer - not classifiable/not likely to be human carcinogen | ISOPROPYL ALCOHOL |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | BUTYL ALCOHOL | |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL | |
| Human nervous system toxicant - moderate evidence | ETHYL ACETATE | |
| Possible human developmental toxicant | DIBUTYL PHTHALATE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | BUTYL ALCOHOL | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | DIBUTYL PHTHALATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | BUTYL ACETATE | |
| One or more animal studies show brain and nervous system effects at high doses | BUTYL ALCOHOL, BENZOPHENONE-1 | |
| Strong evidence of human neurotoxicity | ETHYL ACETATE | |
| One or more animal studies show brain and nervous system effects at moderate doses | CALCIUM PANTOTHENATE | |
| Strong evidence of human neurotoxicity | DIBUTYL PHTHALATE, ISOPROPYL ALCOHOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | BENZOPHENONE-1, DIBUTYL PHTHALATE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | DIBUTYL PHTHALATE | |
| Human skin toxicant - strong evidence | BENZOPHENONE-1 |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | ISOPROPYL ALCOHOL | |
| Persistent, bioaccumulative in wildlife | DIBUTYL PHTHALATE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as expected to be toxic or harmful | NITROCELLULOSE | |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | SILICA, CALCIUM CARBONATE | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | CALCIUM PANTOTHENATE | |
| Limited evidence of sense organ toxicity | ISOPROPYL ALCOHOL, ETHYL ACETATE | |
| One or more animal studies show broad systemic effects at low doses | BENZOPHENONE-1 | |
| Known human respiratory toxicant | DIBUTYL PHTHALATE | |
| Known human lung and skin toxicant | products that may be aerosolized (airborne); products for use on skin | BUTYL ALCOHOL |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | NITROCELLULOSE, ISOPROPYL ALCOHOL | |
| Wildlife and environmental toxicity | DIBUTYL PHTHALATE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as skin irritant | products for use on skin | BUTYL ACETATE |
| One or more animal studies show skin irritation at low doses | CALCIUM CARBONATE | |
| Classified as lung and skin irritant | products that may be aerosolized (airborne); products for use on skin | BUTYL ALCOHOL |
| Classified as irritant | ISOPROPYL ALCOHOL, ETHYL ACETATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Insufficient data to determine safety | DIBUTYL PHTHALATE, BUTYL ALCOHOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DIBUTYL PHTHALATE, ETHYL ACETATE, BUTYL ALCOHOL, BUTYL ACETATE | |
| Not assessed for safety in cosmetics by industry panel | YOLUSIN ESULSONANIDE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | BENZOPHENONE-1 | |
| Not assessed for safety in cosmetics by industry panel | CALCIUM CARBONATE, CALCIUM PANTOTHENATE, FORMALDEHYDE RESIN, PROTEIN, NITROCELLULOSE, ISOPROPYL ALCOHOL |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ETHYL ACETATE, BUTYL ACETATE | |
| Allowed workplace exposures restricted to moderate doses | DIBUTYL PHTHALATE, CALCIUM CARBONATE | |
| Allowed workplace exposures restricted to low doses | BUTYL ALCOHOL | |
| Allowed workplace exposures restricted to high doses | ISOPROPYL ALCOHOL |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SILICA | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | DIBUTYL PHTHALATE |
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