Mary Kate & Ashley Two Eau de Toilette (2005 formulation) || Skin Deep: Cosmetic Safety Reviews

MARY KATE & ASHLEY TWO EAU DE TOILETTE (2005 FORMULATION)

last updated: 04/01/05 brand: Mary Kate and Ashley by Coty, Inc.

SCORE

high hazard (out of 10)

67%

data gap

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79% of fragrance for womens have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: ALCOHOL DENAT, WATER, FRAGRANCE, ETHYLHEXYL METHOXYCINNAMATE, BENZOPHENONE-2, FD AND C YELLOW NO. 6, FD AND C RED NO. 4, FD AND C YELLOW NO. 5, EXT. D AND C VIOLET NO. 2.

Warnings from packaging: Flammable until dry. Do not use near fire, flame or heat.

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ingredients

	score	data gap	concerns
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient)	6	65%	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
EXT D&C VIOLET 2 EXT. D&C VIOLET NO. 2	5	73%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
ALCOHOL DENATURED	5	71%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
BENZOPHENONE-2	5	67%	Endocrine disruption, Allergies/immunotoxicity
FD&C RED 4 FD&C RED NO. 4	1	73%	none identified
FD&C YELLOW 6 FD&C YELLOW NO. 6	1	70%	none identified
FD&C YELLOW 5 FD&C YELLOW NO. 5	2	82%	Neurotoxicity, Organ system toxicity (non-reproductive)
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		FD&C YELLOW 5, BENZOPHENONE-2
Cancer - limited evidence		EXT D&C VIOLET 2, ALCOHOL DENATURED
Cancer - not classifiable/not likely to be human carcinogen		FD&C YELLOW 6, FD&C RED 4

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive system effects at high doses		FD&C YELLOW 6, FD&C YELLOW 5
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of reproductive toxicity		ALCOHOL DENATURED

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		EXT D&C VIOLET 2
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		EXT D&C VIOLET 2

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		FD&C YELLOW 6
One or more animal studies show brain and nervous system effects at very low doses		FD&C YELLOW 5
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		ALCOHOL DENATURED
Human any disruptor - strong evidence		OCTINOXATE (OCTYL METHOXYCINNAMATE), BENZOPHENONE-2

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Human skin toxicant - strong evidence		EXT D&C VIOLET 2, BENZOPHENONE-2
Known human immune system toxicant		FRAGRANCE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Not suspected to be bioaccumulative		ALCOHOL DENATURED

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient)		FD&C YELLOW 6
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		BENZOPHENONE-2
Limited evidence of sense organ toxicity		ALCOHOL DENATURED
One or more animal studies show musculoskeletal effects at very low doses		FD&C YELLOW 5

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		ALCOHOL DENATURED
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		FD&C YELLOW 6, FD&C YELLOW 5, ALCOHOL DENATURED
Used in food or as an additive with limited or no toxicity information available		ALCOHOL DENATURED

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be an environmental toxin		ALCOHOL DENATURED
Wildlife and environmental toxicity		OCTINOXATE (OCTYL METHOXYCINNAMATE)

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		BENZOPHENONE-2
Insufficient data to determine safety		ALCOHOL DENATURED
Not assessed for safety in cosmetics by industry panel		FRAGRANCE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		BENZOPHENONE-2, ALCOHOL DENATURED