EXUVIANCE FROM NEOSTRATA BLEMISH TREATMENT GEL (2005 FORMULATION)
last updated: 04/01/05 brand: Exuviance by NeoStrata
COMPANY POLICIES
Compact for Safe Cosmetics
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Animal Testing Policy |
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used in this product: Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Biochemical or cellular level changes |
Ingredients from packaging: SD ALCOHOL, PROPYLENE GLYCOL, BUTYLENE GLYCOL, PEG-8, POLYACRYLAMIDE, SILICIC ACID, VITAMIN A, ACETATE, ISOPARAFFIN, LAURETH-7, O-ACETYL MANDELIC ACID, CITRIC ACID, TARTARIC ACID.
Directions from packaging: Apply a thin layer to blemished area 1 to 3 times a day.
Warnings from packaging: For external use only. Avoid contact with eyes. Sensitive skin may experience a brief tingling sensation. Discontinue use if signs of irritation appear. Do not use on children.
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ingredients
| score | data gap | concerns | |
| PEG-8 | 6 | 76% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| SD ALCOHOL | 5 | 76% | Cancer, Developmental/reproductive toxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption |
| VITAMIN A | 5 | 70% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| LAURETH-7 | 3 | 100% | Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| CITRIC ACID | 2 | 72% | Violations, restrictions & warnings |
| POLYACRYLAMIDE | 3 | 71% | Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (ACRYLAMIDE) |
| HYDRATED SILICA SILICIC ACID | 2 | 79% | Persistence and bioaccumulation |
| TARTARIC ACID | 1 | 87% | none identified |
| BUTYLENE GLYCOL | 1 | 79% | Irritation (skin, eyes, or lungs) |
| ACETATE | 0 | 100% | none identified |
| ISOPARAFFIN | 0 | 100% | none identified |
| O-ACETYL MANDELIC ACID | 0 | 100% | none identified |
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | VITAMIN A, PROPYLENE GLYCOL | |
| Cancer - limited evidence | SD ALCOHOL | |
| Cancer - not classifiable/not likely to be human carcinogen | HYDRATED SILICA |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | VITAMIN A, BUTYLENE GLYCOL | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL | |
| Limited evidence of reproductive toxicity | SD ALCOHOL |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PROPYLENE GLYCOL, PEG-8, POLYACRYLAMIDE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | VITAMIN A, CITRIC ACID | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin | products for use on damaged skin | PEG-8 |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | SD ALCOHOL | |
| One or more animal studies show brain and nervous system effects at high doses | VITAMIN A, TARTARIC ACID, POLYACRYLAMIDE, PROPYLENE GLYCOL, BUTYLENE GLYCOL |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | BUTYLENE GLYCOL |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL |
Persistence and bioaccumulation*
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Persistent, bioaccumulative in wildlife | SD ALCOHOL | |
| Persistent, bioaccumulative in wildlife and humans | HYDRATED SILICA |
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show musculoskeletal effects at high doses (low dose studies may be unavailable for this ingredient) | CITRIC ACID, VITAMIN A, TARTARIC ACID, BUTYLENE GLYCOL, PROPYLENE GLYCOL, POLYACRYLAMIDE | |
| Limited evidence of sense organ toxicity | PEG-8, SD ALCOHOL |
Multiple, additive exposure sources*
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | VITAMIN A, TARTARIC ACID, PROPYLENE GLYCOL, POLYACRYLAMIDE, PEG-8, CITRIC ACID, BUTYLENE GLYCOL | |
| Used in food or as an additive with limited or no toxicity information available | SD ALCOHOL |
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | VITAMIN A, PROPYLENE GLYCOL, CITRIC ACID, BUTYLENE GLYCOL |
Data gaps*
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | VITAMIN A | |
| Considered safe based on assumption of low absorption | POLYACRYLAMIDE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | BUTYLENE GLYCOL | |
| Not assessed for safety in cosmetics by industry panel | HYDRATED SILICA, TARTARIC ACID, SD ALCOHOL, O-ACETYL MANDELIC ACID, LAURETH-7, ISOPARAFFIN, CITRIC ACID, ACETATE |
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
Biochemical or cellular level changes*
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CITRIC ACID, POLYACRYLAMIDE, PROPYLENE GLYCOL | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | VITAMIN A |
Copyright © 2010 by Environmental Working Group
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