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LISTERINE FRESH CITRUS LISTERINE POCKETMIST ORAL CARE MIST (2006 FORMULATION)

last updated: 05/01/06 brand: Listerine by Pfizer

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.


Ingredients in this product are linked to:
yesCancer
yesDevelopmental/reproductive toxicity
yesViolations, restrictions & warnings
noAllergies/immunotoxicity
yesOther concerns for ingredients used in this product:
Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards


Ingredients from packaging: ACTIVE INGREDIENTS: ALCOHOL, WATER, GLYCERIN, POLOXAMER 407, FLAVORING, MENTHOL, POTASSIUM ACESULFAME, SUCRALOSE, EUCALYPTOL, THYMOL.

Directions from packaging: + Mist 2 or 3 times for Fresh Breath and An Incredibly Clean Mouth Feeling. + NOTE: Trigger must be primed multiple times for initial use.

Warnings from packaging: + Avoid spraying in eyes. + FLAMMABLE. + Keep away from fire or flame. + Keep out of reach of children.

 

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ingredients

     score    data gap       concerns
THYMOL663%Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
ETHANOL
ALCOHOL
(Active Ingredient)
574%Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
UNSPECIFIED FLAVOR
FLAVORING
4100%Miscellaneous
POLOXAMER 407282%Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
MENTHOL385%Organ system toxicity (non-reproductive), Multiple, additive exposure sources
EUCALYPTOL279%none identified
GLYCERIN274%Organ system toxicity (non-reproductive), Occupational hazards
SUCRALOSE195%none identified
POTASSIUM ACESULFAME094%none identified
WATER00%innocuous


Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results   THYMOL, SUCRALOSE, MENTHOL, GLYCERIN, EUCALYPTOL
Cancer - limited evidence   ETHANOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show reproductive effects at high doses   EUCALYPTOL
One or more animal studies show reproductive effects at moderate doses   GLYCERIN, THYMOL
Limited evidence of reproductive toxicity   ETHANOL

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)   THYMOL
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications   THYMOL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study   ETHANOL
One or more animal studies show brain and nervous system effects at high doses   POLOXAMER 407, GLYCERIN
One or more animal studies show brain and nervous system effects at moderate doses   MENTHOL, EUCALYPTOL
One or more animal studies show brain and nervous system effects at low doses   THYMOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show endocrine disruption at moderate doses   THYMOL
One or more animal studies show endocrine system disruption at high doses   EUCALYPTOL, GLYCERIN

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Not suspected to be bioaccumulative   ETHANOL, POLOXAMER 407

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)   EUCALYPTOL
One or more animal studies show broad systemic effects at low doses   POLOXAMER 407, THYMOL
One or more animal studies show sense organ effects at very low doses products for use around the eyes, mouth, or lips MENTHOL, ETHANOL
One or more animal studies show kidney or renal system effects at very low doses   GLYCERIN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Occupational hazards related to handling   THYMOL, ETHANOL
Ingredient not fully labeled - identity unknown   UNSPECIFIED FLAVOR

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Designated as safe for general or specific, limited use in food   MENTHOL, POTASSIUM ACESULFAME, SUCRALOSE, THYMOL, POLOXAMER 407, GLYCERIN, EUCALYPTOL, ETHANOL
Used in food or as an additive with limited or no toxicity information available   MENTHOL, ETHANOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Suspected to be an environmental toxin   POLOXAMER 407
Wildlife and environmental toxicity   THYMOL
Not suspected to be an environmental toxin   ETHANOL

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show skin irritation at moderate doses   THYMOL, MENTHOL, GLYCERIN
One or more animal studies show skin irritation at low doses   ETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Safety assessment was based on related chemical   POLOXAMER 407
Missing safety data noted by cosmetic industry review   POLOXAMER 407, THYMOL
Not assessed for safety in cosmetics by industry panel   POTASSIUM ACESULFAME, SUCRALOSE, UNSPECIFIED FLAVOR
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   POLOXAMER 407
Not assessed for safety in cosmetics by industry panel   MENTHOL, GLYCERIN, EUCALYPTOL, ETHANOL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
Allowed workplace exposures restricted to high doses   ETHANOL
Allowed workplace exposures restricted to moderate doses   GLYCERIN
Allowed workplace exposures restricted to low doses   THYMOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern product conditions ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood   GLYCERIN
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood   EUCALYPTOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood   ETHANOL

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