Dr. Jeannette Graf, M.D. Skin Perfect Microdermabrasion System (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

DR. JEANNETTE GRAF, M.D. SKIN PERFECT MICRODERMABRASION SYSTEM (2006 FORMULATION)

last updated: 11/14/06 brand: Dr. Jeannette Graf, M.D. by

SCORE

high hazard (out of 10)

83%

data gap

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COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: WATER, GLYCINE SOJA (SOYBEAN) OIL, ISOPROPYL PALMITATE, PEG-100 STEARATE, GLYCERYL STEARATE, HAMAMELIS VIRGINIANA (WITCH HAZEL), BUTYLENE GLYCOL, LAC, LACTIC ACID, MILK PROTEIN, ALOE BARBADENSIS, QUILLAJA SAPONARIA BARK EXTRACT, ANTHEMIS NOBILIS FLOWER EXTRACT, CENTAUREA CYANUS FLOWER EXTRACT, CAPRYLIC/CAPRIC TRIGLYCERIDE, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, PROPYLENE GLYCOL, CHAMOMILLA RECUTITA (MATRICARIA) EXTRACT, ARACHIS HYPOGEA (PEANUT) OIL, DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT, ISOPROPYL MYRISTATE, TOCOPHEROL, HYDROLYZED WHEAT PROTEIN, CARBOMER, METHYLPARABEN, DIAZOLIDINYL UREA, PROPYLPARABEN, FRAGRANCE MICRODERMABRASION CREAM PEEL WATER, ALUMINA, GLYCINE SOJA (SOYBEAN) OIL, OLEA EUROPAEA (OLIVE) OIL, ALOE BARBADENSIS, DIMETHICONE, METHYL GLUCETH-20, CETYL ALCOHOL, GLYCERYL STEARATE, STEARIC ACID, PEG-100 STEARATE, CARBOMER, ALTHEA OFFICINALIS ROOT EXTRACT, HEDERA HELIX (IVY) EXTRACT, ANACYCLUS PYRETHRUM ROOT EXTRACT, CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT, SAMBUCUS NIGRA FLOWER EXTRACT, HAMAMELIS VIRGINIANA (WITCH HAZEL) EXTRACT, HYDROLYZED SOY PROTEIN, LECITHIN, RETINYL PALMITATE, PANTOTHENIC ACID, CALCIUM ASCORBATE, TOCOPHEROL, FRAGRANCE, PHENOXYETHANOL, METHYLPARABEN, PROPYLPARABEN, BHT SKIN PERFECT POST RINSE WATER, HAMAMELIS VIRGINIANA (WITCH HAZEL) DISTILLATE, BUTYLENE GLYCOL, DIPROPYLENE GLYCOL, PPG-2 ISODECETH-12, PROPYLENE GLYCOL, SALICYLIC ACID, FRAGRANCE, ASCORBIC ACID, CAPRYLIC/CAPRIC TRIGLYCERIDE, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, PROPYLENE GLYCOL, CHAMOMILLA RECUTITA (MATRICARIA) EXTRACT, ARACHIS HYPOGEA (PEANUT) OIL, DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT, ISOPROPYL MYRISTATE, TOCOPHEROL, HYDROLYZED WHEAT PROTEIN, PHENOXYETHANOL, DMDM HYDANTOIN, BENZOPHENONE-4, TETRASODIUM EDTA, CITRIC ACID, YELLOW 6 SKIN PERFECT NIGHT REVIVE COMPLEX WATER, GLYCINE SOJA (SOYBEAN) OIL, OLEA EUROPAEA (OLIVE) OIL, ALOE BARBADENSIS, METHYL GLUCETH-20, THIOCTIC ACID, CETYL ALCOHOL, GLYCERYL STEARATE, STEARIC ACID, PEG-100 STEARATE, HYALURONIC ACID, DIMETHYL MEA, CYCLOMETHICONE, DIMETHICONE, CALCIUM ASCORBATE, HYDROLYZED SOY PROTEIN, ALTHEA OFFICINALIS ROOT EXTRACT, ANACYCLUS PYRETHRUM ROOT EXTRACT, CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT, SAMBUCUS NIGRA FLOWER EXTRACT, HAMAMELIS VIRGINIANA (WITCH HAZEL) EXTRACT, CAPRYLIC/CAPRIC TRIGLYCERIDE, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, PROPYLENE GLYCOL, CHAMOMILLA RECUTITA (MATRICARIA) EXTRACT, ARACHIS HYPOGEA (PEANUT) OIL, DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT, ISOPROPYL MYRISTATE, TOCOPHEROL, UBIQUINONE, HYDROLYZED WHEAT PROTEIN, KERATIN AMINO ACIDS, RETINYL PALMITATE, PANTOTHENIC ACID, TOCOPHERYL ACETATE, SODIUM PCA, ETHYLHEXYL METHOXYCINNAMATE, PHENOXYETHANOL, METHYLPARABEN, PROPYLPARABEN, BHT

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
DMDM HYDANTOIN	7	71%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient)	8	65%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
PEG-100 STEARATE	4	69%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
SALICYLIC ACID	7	66%	Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
ALUMINA	6	85%	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
LECITHIN	3	70%	Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
BHT	6	61%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
DIAZOLIDINYL UREA	6	59%	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
LACTIC ACID	5	70%	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
RETINYL PALMITATE	5	68%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
DIMETHYL MEA	4	80%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Occupational hazards
FD&C YELLOW 6	4	70%	Violations, restrictions & warnings
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
SULISOBENZONE (BENZOPHENONE-4) (Active Ingredient)	3	66%	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
DIMETHICONE	2	74%	Violations, restrictions & warnings
CITRIC ACID	3	72%	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
MILK PROTEIN	2	92%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
CYCLOMETHICONE	2	83%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
TETRASODIUM EDTA	2	81%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
STEARIC ACID	2	74%	Neurotoxicity, Irritation (skin, eyes, or lungs)
SODIUM PCA	2	71%	Contamination concerns (NITROSAMINES)
HAMAMELIS VIRGINIANA (WITCH HAZEL)	1	97%	none identified
HYDROLYZED WHEAT PROTEIN	1	95%	Allergies/immunotoxicity
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	none identified
ASCORBIC ACID (VITAMIN C)	1	91%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
GLYCINE SOJA (SOYBEAN) OIL	1	88%	none identified
OLEA EUROPAEA (OLIVE) OIL	1	88%	Irritation (skin, eyes, or lungs)
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ISOPROPYL PALMITATE	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
VITAMIN B3 PANTOTHENIC ACID	1	87%	none identified
THIOCTIC ACID	1	87%	none identified
ISOPROPYL MYRISTATE	1	86%	Irritation (skin, eyes, or lungs)
ARACHIS HYPOGAEA (PEANUT) OIL ARACHIS HYPOGEA (PEANUT) OIL	1	85%	Irritation (skin, eyes, or lungs), Enhanced skin absorption
DIPROPYLENE GLYCOL	1	84%	Irritation (skin, eyes, or lungs)
UBIQUINONE	1	84%	none identified
ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT ANTHEMIS NOBILIS FLOWER EXTRACT	1	80%	Enhanced skin absorption
BUTYLENE GLYCOL	1	79%	Irritation (skin, eyes, or lungs)
ALOE BARBADENSIS (ALOE VERA)	1	72%	none identified
ALTHAEA OFFICINALIS (MARSHMALLOW) EXTRACT ALTHEA OFFICINALIS ROOT EXTRACT	0	100%	none identified
CENTAUREA CYANUS (CORNFLOWER) FLOWER EXTRACT CENTAUREA CYANUS FLOWER EXTRACT	0	100%	none identified
CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT	0	100%	none identified
DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT	0	100%	none identified
HAMAMELIS VIRGINIANA (WITCH HAZEL) DISTILLATE	0	100%	none identified
HAMAMELIS VIRGINIANA (WITCH HAZEL) EXTRACT	0	100%	none identified
HEDERA HELIX (IVY) EXTRACT	0	100%	none identified
KERATIN AMINO ACIDS	0	100%	none identified
PPG-2-ISODECETH-12	0	100%	none identified
QUILLAJA SAPONARIA (SOAPBARK) BARK EXTRACT QUILLAJA SAPONARIA BARK EXTRACT	0	100%	none identified
ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT	0	100%	none identified
SAMBUCUS NIGRA (ELDER) FLOWER EXTRACT SAMBUCUS NIGRA FLOWER EXTRACT	0	100%	none identified
ANACYCLUS PYRETHRUM ROOT EXTRACT	0	100%	none identified
CHAMOMILLA RECUTITA (MATRICARIA) EXTRACT	0	100%	none identified
LAC	0	100%	none identified
METHYL GLUCETH-20	0	100%	none identified
HYALURONIC ACID	0	94%	none identified
HYDROLYZED GLYCINE SOJA (SOY) PROTEIN HYDROLYZED SOY PROTEIN	0	94%	none identified
CALCIUM ASCORBATE	0	93%	none identified
CARBOMER	0	93%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not likely to be mutagenic in humans		SULISOBENZONE (BENZOPHENONE-4)
One or more in vitro tests non-mammalian cells show positive mutation results		PHENOXYETHANOL, OLEA EUROPAEA (OLIVE) OIL, HAMAMELIS VIRGINIANA (WITCH HAZEL), GLYCINE SOJA (SOYBEAN) OIL, ARACHIS HYPOGAEA (PEANUT) OIL, ALOE BARBADENSIS (ALOE VERA)
One or more animal studies show tumor formation at moderate doses		PEG-100 STEARATE, ALUMINA
One or more in vitro tests on mammalian cells show positive mutation results		TOCOPHERYL ACETATE, PROPYLPARABEN, TOCOPHEROL, METHYLPARABEN, PROPYLENE GLYCOL
Cancer - not classifiable/not likely to be human carcinogen		SALICYLIC ACID
One or more in vitro tests on mammalian cells show positive mutation results		ASCORBIC ACID (VITAMIN C), DIAZOLIDINYL UREA
Cancer - not classifiable/not likely to be human carcinogen		LACTIC ACID
Cancer - limited evidence		RETINYL PALMITATE
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - not classifiable/not likely to be human carcinogen		FD&C YELLOW 6, BHT

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive system effects at high doses		FD&C YELLOW 6, PEG-100 STEARATE, BUTYLENE GLYCOL, BHT
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE), ALOE BARBADENSIS (ALOE VERA)
One or more animal studies show reproductive effects at moderate doses		UBIQUINONE, SALICYLIC ACID, PROPYLENE GLYCOL
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE,
One or more animal studies show any effects at low doses		PROPYLPARABEN
Human nervous system toxicant - moderate evidence		ALUMINA

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PEG-100 STEARATE, SODIUM PCA, SALICYLIC ACID, LACTIC ACID, LECITHIN, PROPYLENE GLYCOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ALOE BARBADENSIS (ALOE VERA), DIAZOLIDINYL UREA
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		SALICYLIC ACID, RETINYL PALMITATE, LACTIC ACID, CITRIC ACID
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		DMDM HYDANTOIN, SALICYLIC ACID, PHENOXYETHANOL, DMDM HYDANTOIN
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits		LACTIC ACID
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes	products for use around the eyes	FD&C YELLOW 6

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		UBIQUINONE, RETINYL PALMITATE, PROPYLENE GLYCOL, FD&C YELLOW 6, LACTIC ACID, DIPROPYLENE GLYCOL, BUTYLENE GLYCOL, DIAZOLIDINYL UREA
One or more animal studies show brain and nervous system effects at moderate doses		LECITHIN, METHYLPARABEN, PHENOXYETHANOL, VITAMIN B3
One or more animal studies show brain and nervous system effects at low doses		BHT, SALICYLIC ACID
One or more animal studies show brain and nervous system effects at very low doses		STEARIC ACID
One or more animal studies show brain and nervous system effects at moderate doses		ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Strong evidence of human neurotoxicity		ALUMINA
Moderate evidence of human neurotoxicity		FRAGRANCE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Associated with endocrine disruption		SULISOBENZONE (BENZOPHENONE-4)
One or more animal studies show endocrine system disruption at high doses		SODIUM PCA, DIAZOLIDINYL UREA, BUTYLENE GLYCOL, BHT, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Human any disruptor - strong evidence		METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), PROPYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE), HYDROLYZED WHEAT PROTEIN
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
Human immune system toxicant - moderate evidence		MILK PROTEIN, DIMETHYL MEA
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE, METHYLPARABEN, SULISOBENZONE (BENZOPHENONE-4), PROPYLPARABEN
Known human immune system toxicant		FRAGRANCE, DMDM HYDANTOIN, DIAZOLIDINYL UREA, BHT

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be persistent		CETYL ALCOHOL
Not suspected to be bioaccumulative		ALUMINA
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE, SALICYLIC ACID
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, FD&C YELLOW 6, VITAMIN B3, STEARIC ACID, SODIUM PCA, ISOPROPYL MYRISTATE
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CYCLOMETHICONE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		THIOCTIC ACID,
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		ALUMINA
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		GLYCINE SOJA (SOYBEAN) OIL, DIAZOLIDINYL UREA
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	PROPYLENE GLYCOL, DIPROPYLENE GLYCOL, CETYL ALCOHOL, BUTYLENE GLYCOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		TOCOPHERYL ACETATE, OLEA EUROPAEA (OLIVE) OIL, GLYCERYL MONOSTEARATE, DMDM HYDANTOIN, UBIQUINONE
Limited evidence of skin toxicity		RETINYL PALMITATE, PEG-100 STEARATE, PROPYLPARABEN
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	SULISOBENZONE (BENZOPHENONE-4)
One or more animal studies show broad systemic effects at low doses		ISOPROPYL PALMITATE, BHT
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	LACTIC ACID, PHENOXYETHANOL, SALICYLIC ACID, CITRIC ACID
Possible human immune system toxicant		MILK PROTEIN, DIMETHYL MEA
Limited evidence of eye toxicity	products for use around the eyes	TETRASODIUM EDTA
Known human any toxicant		METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		DIMETHYL MEA
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PEG-100 STEARATE, TOCOPHERYL ACETATE, TOCOPHEROL, TETRASODIUM EDTA, STEARIC ACID, SALICYLIC ACID, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, RETINYL PALMITATE, QUILLAJA SAPONARIA (SOAPBARK) BARK EXTRACT, PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN, LECITHIN, LACTIC ACID, ISOPROPYL PALMITATE, ISOPROPYL MYRISTATE, GLYCERYL MONOSTEARATE, FD&C YELLOW 6, DIMETHICONE, CITRIC ACID, CETYL ALCOHOL, CALCIUM ASCORBATE, ARACHIS HYPOGAEA (PEANUT) OIL, ASCORBIC ACID (VITAMIN C), BHT, BUTYLENE GLYCOL, ALOE BARBADENSIS (ALOE VERA), ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Used in food or as an additive with limited or no toxicity information available		SALICYLIC ACID, DIMETHYL MEA, LECITHIN

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		ALUMINA, CETYL ALCOHOL, CYCLOMETHICONE
Wildlife and environmental toxicity		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at low doses		ARACHIS HYPOGAEA (PEANUT) OIL, BHT, ISOPROPYL PALMITATE, METHYLPARABEN, OLEA EUROPAEA (OLIVE) OIL
One or more animal studies show skin irritation at moderate doses		SALICYLIC ACID, DIMETHYL MEA, CYCLOMETHICONE
One or more animal studies show skin irritation at low doses		STEARIC ACID, TETRASODIUM EDTA
One or more animal studies show skin irritation at moderate doses		ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, CITRIC ACID
One or more animal studies show skin irritation at very low doses		PEG-100 STEARATE, LACTIC ACID, CETYL ALCOHOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	SULISOBENZONE (BENZOPHENONE-4), ISOPROPYL MYRISTATE, DMDM HYDANTOIN, DIPROPYLENE GLYCOL, BUTYLENE GLYCOL
Classified as skin irritant		PROPYLENE GLYCOL, PHENOXYETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		CALCIUM ASCORBATE, PROPYLENE GLYCOL, PEG-100 STEARATE, ASCORBIC ACID (VITAMIN C)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		PEG-100 STEARATE
Missing safety data noted by cosmetic industry review		ALOE BARBADENSIS (ALOE VERA)
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHERYL ACETATE, SULISOBENZONE (BENZOPHENONE-4), TETRASODIUM EDTA, TOCOPHEROL, STEARIC ACID, RETINYL PALMITATE, METHYLPARABEN, PHENOXYETHANOL, PROPYLPARABEN, ISOPROPYL MYRISTATE, ISOPROPYL PALMITATE, GLYCERYL MONOSTEARATE, DMDM HYDANTOIN, DIPROPYLENE GLYCOL, DIMETHICONE, CETYL ALCOHOL, CYCLOMETHICONE, CARBOMER, BUTYLENE GLYCOL, BHT, ASCORBIC ACID (VITAMIN C), ARACHIS HYPOGAEA (PEANUT) OIL, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Not assessed for safety in cosmetics by industry panel		METHYL GLUCETH-20, THIOCTIC ACID, LAC, CHAMOMILLA RECUTITA (MATRICARIA) EXTRACT, ANACYCLUS PYRETHRUM ROOT EXTRACT, VITAMIN B3, UBIQUINONE, SAMBUCUS NIGRA (ELDER) FLOWER EXTRACT, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, QUILLAJA SAPONARIA (SOAPBARK) BARK EXTRACT, PPG-2-ISODECETH-12, OLEA EUROPAEA (OLIVE) OIL, KERATIN AMINO ACIDS, MILK PROTEIN, HYDROLYZED WHEAT PROTEIN, HYDROLYZED GLYCINE SOJA (SOY) PROTEIN, HEDERA HELIX (IVY) EXTRACT, HAMAMELIS VIRGINIANA (WITCH HAZEL) EXTRACT, HAMAMELIS VIRGINIANA (WITCH HAZEL) DISTILLATE, HAMAMELIS VIRGINIANA (WITCH HAZEL), GLYCINE SOJA (SOYBEAN) OIL, DIMETHYL MEA, FRAGRANCE, CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT, DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT, CITRIC ACID, CENTAUREA CYANUS (CORNFLOWER) FLOWER EXTRACT, CAPRYLIC/ CAPRIC TRIGLYCERIDE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, ALUMINA, ALTHAEA OFFICINALIS (MARSHMALLOW) EXTRACT

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		ALUMINA
Allowed workplace exposures restricted to low doses		TETRASODIUM EDTA
Allowed workplace exposures restricted to low doses		BHT
No workplace limits set		LACTIC ACID
Allowed workplace exposures restricted to low doses		DIMETHYL MEA, PHENOXYETHANOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood		PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		METHYLPARABEN
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CYCLOMETHICONE, CITRIC ACID
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		THIOCTIC ACID, UBIQUINONE
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT