Mirenesse Dolce Vita Lips Collection (2006 formulation) || Skin Deep: Cosmetic Safety Reviews

MIRENESSE DOLCE VITA LIPS COLLECTION (2006 FORMULATION)

last updated: 11/14/06 brand: Mirenesse by

SCORE

high hazard (out of 10)

87%

data gap

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100% of lip liners have lower concerns
100% of lipsticks have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: HYDROGENATED POLYISOBUTENE, TRIMETHYLOLPROPANE TRIISOSTEARATE, POLYBUTENE, POLYISOBUTENE, SILICA DIMETHYL SILYATE, VP/ EICOSEIN COPLYMER, DEXTRIN PALMITATE, METHYLPARABEN, BISABOLOL, FRAGRANCE, TOCOPHEROL, TOCOPHEROL ACETATE, ASCORBYL PALMITATE, METHICONE, MICA (MC), TITANIUM DIOXIDE (MC), IRON OXIDES (MC), RED 6 (CL15850) (MC), RED 7 LAKE (CL15850) (MC), BLU1! LAKE (CL42090) (MC), RICINUS COMUNIS OIL, OZOKERITE, ISOSTEARYL ISOSTEARATE, CETYL LACTATE, OLEYL ALCOHOL, DIPENTAERYTHRITYL HEXAHYDOXYSTEARATE/ HEXASTEARATE/ HEXAROSINATE, MICROCRYSTALLINE WAX, ARACHIDYL PROPIONATE, ISOPROPYL MYRISTATE, SUCROSE DISTEARATE, CETYL ALCOHOL, COPERNICA CERIFERA WAX, METHYL METHACRYLATE CROSSPOLYMER, BARIUM SULFATE, PHYTOSPHINGOSINE, ASCORBYL PALMITATE, ALLANTOIN, TOCOPHERYL ACETATE, SORBITAN SESQUIOLEATE, LINUMUSUTASSIMUM SEED OIL, TOCOPHEROL, PROPYLPARABEN, BHT, FRAGRANCE, ACETYLATED GLYCOL STEARATE, IRON OXIDES (MC), TITANIUM DIOXIDE (MC), MICA (MC), ULTRAMARINES (MC), CARMINE (MC), HYDROGENATED COCO-GLYCERIDES, JAPAN WAX, STEARIC ACID, TRIETHYLHEXANOIN, HYDROGENATED CASTOR OIL, ACETYLATED SUCROSE DISTEARATE, CERESIN, LANOLIN, HYDROGENATED COCONUT OIL, LARD GLYCERIDES, HYDROGENATED HI-ERUCIC ACID RAPE SEED OIL, MICROCRYSTALLINE WAX, CHOLESTERYL HYDROXYSTEARATE, CHOLESTERYL/ BEHENYL/OCTYLDODECYL/LAUROYL GLUTAMATE, PROPYLPARABEN, TITANIUM DIOXIDE (MC), IRON OXIDES (MC), RED 7 (MC), BLUE 1 LAKE (MC), MANGANESE VIOLET (MC), MICA (MC), POLYBUTENE, OCTYLDODECANOL, CERA MICROCRISTALLINA, POLYETHYLENE, ETHYLHEXYL METHOXYCINNAMATE, PARAFFIN, BIS-DIGLYCERYL POLYACYLADIPATE-2, MICA, BUTYL METHOXYDIBENZOYLMETHANE, PENTAERYTHRITYL TETRAISOSTEARATE, SILICA, ATELOCOLLAGEN, ACRYLATES COPOLYMER, POLYETHYLENE TEREPHTHALATE, DIMETHYL SILYLATE, SODIUM CHONDROTIN SUFATE PROPYLPARABEN, ISOPROPYLPARABEN, BUTYLPARABEN, ISOBUTYLPARABEN, PROPYLENE GLYCOL, BHT, ASCORBYL PALMITATE, GLYCERYL STEARATE, CITRIC ACID, CI 77891, CI 77491, OCTYLDODECANOL, ETHYLCELLULOSE, SILICA DIMETHYL SILYLATE, DIISOSTEARYL MALATE, HYDROGENATED POLYISOBUTENE, DISTEARDIMONIUM HECTORITE, PANTHENOL, TOCOPHEROL ACETATE, ASCORBYL PALMITATE, L-ARGININE, BENZYL NICOTINATE, MICROCRYSTALLINE WAX, POLYETHYLENE, PROPYLENE CARBONATE, PHENOXYETHANOL, METHYLPARABEN PROPYLPARABEN, FRAGRANCE, MICA (MC), TITANIUM DIOXIDE (MC), IRON OXIDES (MC), ULTRAMARINES (MC), MANGANESE VIOLET (MC), FERRIC FERROCYANIDE (MC), CHROMIUM OXIDE GREENS (MC), RED 6 (MC), RED 7 LAKE (MC), YELLOW 5 LAKE (MC), RED 30 LAKE (MC), BLUE 1 LAKE (MC), CARMINE (MC).

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ingredients

	score	data gap	concerns
METHYLPARABEN	10	63%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
POLYETHYLENE	5	69%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
OCTINOXATE (OCTYL METHOXYCINNAMATE) ETHYLHEXYL METHOXYCINNAMATE (Active Ingredient)	8	65%	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
SILICA	1	69%	Biochemical or cellular level changes
BARIUM SULFATE	6	80%	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
BUTYLPARABEN	6	79%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
BHT	6	61%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
D&C RED 30 LAKE (May Contain)	4	72%	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation
PROPYLPARABEN	5	71%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
FD&C BLUE 1 ALUMINUM LAKE BLUE 1 LAKE (May Contain)	4	91%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5 ALUMINUM LAKE YELLOW 5 LAKE (May Contain)	4	91%	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
TITANIUM DIOXIDE (NON-NANO) (May Contain)	1	81%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
CETYL LACTATE	4	74%	Violations, restrictions & warnings
D&C RED 7 LAKE RED 7 LAKE (CL15850) (May Contain)	4	73%	Developmental/reproductive toxicity, Neurotoxicity
LANOLIN	4	71%	Allergies/immunotoxicity
PHENOXYETHANOL	4	67%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
CHROMIUM OXIDE GREENS (May Contain)	3	86%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
ISOPROPYLPARABEN	3	84%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ISOBUTYLPARABEN	3	83%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ARGININE	3	79%	Neurotoxicity, Organ system toxicity (non-reproductive)
FERRIC FERROCYANIDE (May Contain)	3	76%	Organ system toxicity (non-reproductive), Occupational hazards
CI 77491	2	76%	Persistence and bioaccumulation, Occupational hazards, Biochemical or cellular level changes
ACRYLATES COPOLYMER	3	75%	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
D&C RED 6 RED 6 (CL15850) (May Contain)	0	75%	none identified
D&C RED 7 (May Contain)	0	75%	none identified
MICA (May Contain)	3	75%	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
CITRIC ACID	3	72%	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
ULTRAMARINES (May Contain)	2	90%	Multiple, additive exposure sources
PANTHENOL	2	88%	Multiple, additive exposure sources
TOCOPHEROL	2	87%	Contamination concerns (HYDROQUINONE)
IRON OXIDES (May Contain)	2	85%	Persistence and bioaccumulation, Enhanced skin absorption
CI 42090 BLU1! LAKE (CL42090) (May Contain)	2	83%	Neurotoxicity
CASTOR OIL RICINUS COMUNIS OIL	2	80%	Developmental/reproductive toxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PARAFFIN	2	80%	Organ system toxicity (non-reproductive), Occupational hazards
STEARIC ACID	2	74%	Neurotoxicity, Irritation (skin, eyes, or lungs)
AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE) (Active Ingredient)	2	73%	Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE)
CARMINE (May Contain)	0	94%	none identified
ETHYLCELLULOSE	1	94%	Organ system toxicity (non-reproductive)
MANGANESE VIOLET (May Contain)	0	94%	none identified
POLYISOBUTENE	1	94%	Organ system toxicity (non-reproductive)
BENZYL NICOTINATE	1	93%	Organ system toxicity (non-reproductive)
CERESIN	0	93%	none identified
MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA)	1	93%	Organ system toxicity (non-reproductive)
POLYETHYLENE TEREPHTHALATE	1	93%	Organ system toxicity (non-reproductive)
POLYBUTENE	1	92%	Organ system toxicity (non-reproductive)
OZOKERITE	1	91%	none identified
ASCORBYL PALMITATE (VITAMIN C PALMITATE)	1	88%	none identified
GLYCERYL MONOSTEARATE GLYCERYL STEARATE	1	88%	none identified
SORBITAN SESQUIOLEATE	1	88%	none identified
CETYL ALCOHOL	1	87%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
OCTYLDODECANOL	1	87%	Irritation (skin, eyes, or lungs)
OLEYL ALCOHOL	1	87%	Irritation (skin, eyes, or lungs)
LINUM USITATISSIMUM (LINSEED) SEED OIL LINUMUSUTASSIMUM SEED OIL	1	87%	Irritation (skin, eyes, or lungs)
ISOPROPYL MYRISTATE	1	86%	Irritation (skin, eyes, or lungs)
PROPYLENE CARBONATE	1	85%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
BISABOLOL	1	80%	Enhanced skin absorption
SODIUM CHONDROITIN SULFATE SODIUM CHONDROTIN SUFATE	1	80%	none identified
ACETYLATED GLYCOL STEARATE	0	100%	none identified
BIS-DIGLYCERYL POLYACYLADIPATE-2	0	100%	none identified
CHOLESTERYL HYDROXYSTEARATE	0	100%	none identified
CHOLESTERYL/ BEHENYL/ OCTYLDODECYL LAUROYL GLUTAMATE	0	100%	none identified
DEXTRIN PALMITATE	0	100%	none identified
DIMETHYL SILYLATE	0	100%	none identified
DISTEARDIMONIUM HECTORITE	0	100%	none identified
HYDROGENATED COCO-GLYCERIDES	0	100%	none identified
HYDROGENATED POLYISOBUTENE	0	100%	none identified
LARD GLYCERIDES	0	100%	none identified
PENTAERYTHRITYL TETRAISOSTEARATE	0	100%	none identified
PHYTOSPHINGOSINE	0	100%	none identified
RHUS SUCCEDANEA (JAPANESE) WAX JAPAN WAX	0	100%	none identified
SILICA DIMETHYL SILYLATE SILICA DIMETHYL SILYATE	0	100%	none identified
TRIETHYLHEXANOIN	0	100%	none identified
ACETYLATED SUCROSE DISTEARATE	0	100%	none identified
ATELOCOLLAGEN	0	100%	none identified
DIPENTAERYTHRITYL HEXAHYDROXYSTEARATE/HEXASTEARATE/HEXARO SINATE DIPENTAERYTHRITYL HEXAHYDOXYSTEARATE/ HEXASTEARATE/ HEXAROSINATE	0	100%	none identified
HYDROGENATED RAPESEED OIL HYDROGENATED HI-ERUCIC ACID RAPE SEED OIL	0	100%	none identified
METHICONE	0	99%	none identified
ALLANTOIN	0	94%	none identified
DIISOSTEARYL MALATE	0	94%	none identified
ISOSTEARYL ISOSTEARATE	0	94%	none identified
METHYL METHACRYLATE CROSSPOLYMER	0	94%	none identified
VP/ EICOSENE COPOLYMER VP/ EICOSEIN COPLYMER	0	94%	none identified
SUCROSE DISTEARATE	0	94%	none identified
TRIMETHYLOLPROPANE TRIISOSTEARATE	0	94%	none identified
ARACHIDYL PROPIONATE	0	93%	none identified
COPERNICIA CERIFERA (CARNAUBA) WAX COPERNICA CERIFERA WAX	0	93%	none identified
HYDROGENATED CASTOR OIL	0	93%	none identified
HYDROGENATED COCONUT OIL	0	93%	none identified

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		LINUM USITATISSIMUM (LINSEED) SEED OIL, PHENOXYETHANOL
One or more animal studies show tumor formation at moderate doses		POLYETHYLENE TEREPHTHALATE, PARAFFIN
One or more in vitro tests on mammalian cells show positive mutation results		CI 42090, TOCOPHERYL ACETATE, TOCOPHEROL, TITANIUM DIOXIDE (NON-NANO), PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN, BUTYLPARABEN, BARIUM SULFATE, ARGININE,
One or more in vitro tests on mammalian cells show positive mutation results		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Cancer - not classifiable/not likely to be human carcinogen		CETYL LACTATE
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - not classifiable/not likely to be human carcinogen		CI 77491, POLYETHYLENE, CHROMIUM OXIDE GREENS, BHT

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		SODIUM CHONDROITIN SULFATE, BHT
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, ARGININE
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show any effects at very low doses		BUTYLPARABEN
Human nervous system toxicant - moderate evidence		FD&C YELLOW 5 ALUMINUM LAKE, FD&C BLUE 1 ALUMINUM LAKE, D&C RED 7 LAKE, D&C RED 30 LAKE, BARIUM SULFATE
Limited evidence of reproductive toxicity		CASTOR OIL

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PROPYLENE GLYCOL, CETYL LACTATE, POLYETHYLENE, ACRYLATES COPOLYMER, D&C RED 7 LAKE, D&C RED 30 LAKE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID, PHENOXYETHANOL, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits		CETYL LACTATE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at high doses		SODIUM CHONDROITIN SULFATE, ULTRAMARINES, POLYETHYLENE, PROPYLENE GLYCOL
One or more animal studies show brain and nervous system effects at moderate doses		PHENOXYETHANOL, BISABOLOL, METHYLPARABEN, FERRIC FERROCYANIDE
One or more animal studies show brain and nervous system effects at low doses		BHT
One or more animal studies show brain and nervous system effects at very low doses		CI 42090, STEARIC ACID, ARGININE
Moderate evidence of human neurotoxicity		FRAGRANCE
Strong evidence of human neurotoxicity		FD&C YELLOW 5 ALUMINUM LAKE, FD&C BLUE 1 ALUMINUM LAKE, D&C RED 7 LAKE, D&C RED 30 LAKE, BARIUM SULFATE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		SODIUM CHONDROITIN SULFATE, BISABOLOL, BHT
One or more studies show weak endocrine disruption		ISOPROPYLPARABEN
One or more animal studies show endocrine disruption at moderate doses		ISOBUTYLPARABEN, ARGININE
Human any disruptor - strong evidence		PROPYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), METHYLPARABEN, BUTYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show gastrointestinal effects at moderate doses		MICA
Associated with immunotoxicity		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show immune effects at low doses		TITANIUM DIOXIDE (NON-NANO)
Human immune system toxicant - moderate evidence		POLYETHYLENE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN, ISOPROPYLPARABEN, ISOBUTYLPARABEN, BUTYLPARABEN
Known human immune system toxicant		LANOLIN, BHT, FRAGRANCE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Not suspected to be bioaccumulative		POLYBUTENE, TITANIUM DIOXIDE (NON-NANO), POLYISOBUTENE, POLYETHYLENE TEREPHTHALATE, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), CHROMIUM OXIDE GREENS
Not suspected to be persistent		CETYL ALCOHOL
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Persistent, bioaccumulative in wildlife		D&C RED 30 LAKE
Persistent, bioaccumulative in wildlife and humans		IRON OXIDES, BARIUM SULFATE, MICA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as expected to be toxic or harmful		POLYBUTENE, POLYISOBUTENE, POLYETHYLENE TEREPHTHALATE, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), ETHYLCELLULOSE
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		BISABOLOL, ULTRAMARINES, SODIUM CHONDROITIN SULFATE, STEARIC ACID, PANTHENOL, ISOPROPYL MYRISTATE, ASCORBYL PALMITATE (VITAMIN C PALMITATE), LINUM USITATISSIMUM (LINSEED) SEED OIL
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	SORBITAN SESQUIOLEATE, SILICA, PROPYLENE GLYCOL, PARAFFIN, OZOKERITE, OLEYL ALCOHOL, OCTYLDODECANOL, CETYL ALCOHOL, CASTOR OIL
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		CI 42090
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		GLYCERYL MONOSTEARATE, TOCOPHERYL ACETATE, CHROMIUM OXIDE GREENS
Limited evidence of sense organ toxicity		PROPYLPARABEN, ISOPROPYLPARABEN, ISOBUTYLPARABEN, BUTYLPARABEN, FD&C YELLOW 5 ALUMINUM LAKE, BARIUM SULFATE, FD&C BLUE 1 ALUMINUM LAKE
One or more animal studies show broad systemic effects at low doses		BENZYL NICOTINATE,
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	PROPYLENE CARBONATE
One or more animal studies show blood effects at low doses		BHT
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	PHENOXYETHANOL, CITRIC ACID
One or more animal studies show cardiovascular effects at very low doses		TITANIUM DIOXIDE (NON-NANO), ARGININE
Possible human respiratory toxicant		MICA, POLYETHYLENE
Known human respiratory toxicant		FERRIC FERROCYANIDE, METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		CI 77491, HYDROGENATED RAPESEED OIL, TOCOPHERYL ACETATE, TOCOPHEROL, TITANIUM DIOXIDE (NON-NANO), IRON OXIDES, STEARIC ACID, PROPYLPARABEN, PROPYLENE GLYCOL, POLYISOBUTENE, POLYETHYLENE, PARAFFIN, METHYLPARABEN, METHICONE, LANOLIN, ISOPROPYL MYRISTATE, GLYCERYL MONOSTEARATE, FD&C BLUE 1 ALUMINUM LAKE, ETHYLCELLULOSE, CITRIC ACID, CETYL ALCOHOL, CASTOR OIL, COPERNICIA CERIFERA (CARNAUBA) WAX, CARMINE, BHT, BUTYLPARABEN, ASCORBYL PALMITATE (VITAMIN C PALMITATE), ARGININE
Used in food or as an additive with limited or no toxicity information available		ULTRAMARINES, PANTHENOL

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Suspected to be an environmental toxin		CHROMIUM OXIDE GREENS, CETYL ALCOHOL
Not suspected to be an environmental toxin		POLYBUTENE, TITANIUM DIOXIDE (NON-NANO), POLYISOBUTENE, POLYETHYLENE TEREPHTHALATE, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), ETHYLCELLULOSE, BARIUM SULFATE
Wildlife and environmental toxicity		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Wildlife and environmental toxicity		PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		TITANIUM DIOXIDE (NON-NANO), SORBITAN SESQUIOLEATE, PARAFFIN, OZOKERITE, ETHYLCELLULOSE, CITRIC ACID, BUTYLPARABEN, BISABOLOL
One or more animal studies show skin irritation at low doses		LINUM USITATISSIMUM (LINSEED) SEED OIL, STEARIC ACID, METHYLPARABEN, BHT
One or more animal studies show skin irritation at very low doses		OLEYL ALCOHOL, OCTYLDODECANOL, ISOPROPYL MYRISTATE, CETYL ALCOHOL, CASTOR OIL
Classified as skin irritant		PROPYLENE GLYCOL, PROPYLENE CARBONATE, PHENOXYETHANOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		ISOPROPYLPARABEN, PROPYLENE GLYCOL
Pesticide inert of potential toxicological concern		POLYBUTENE
Safety assessment was based on related chemical		ISOBUTYLPARABEN, HYDROGENATED CASTOR OIL, CASTOR OIL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHERYL ACETATE, POLYBUTENE
Considered safe based on assumption of low absorption		ACRYLATES COPOLYMER, POLYETHYLENE
Missing safety data noted by cosmetic industry review		POLYETHYLENE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TOCOPHEROL, STEARIC ACID, SORBITAN SESQUIOLEATE, PROPYLENE CARBONATE, PROPYLPARABEN, PHENOXYETHANOL, POLYETHYLENE, PARAFFIN, OCTYLDODECANOL, OLEYL ALCOHOL, OZOKERITE, METHYLPARABEN, COPERNICIA CERIFERA (CARNAUBA) WAX, PANTHENOL, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), METHICONE, HYDROGENATED COCONUT OIL, ISOPROPYL MYRISTATE, LANOLIN, GLYCERYL MONOSTEARATE, CERESIN, HYDROGENATED CASTOR OIL, CETYL ALCOHOL, BUTYLPARABEN, CASTOR OIL, BISABOLOL, ARACHIDYL PROPIONATE, BHT
Not assessed for safety in cosmetics by industry panel		LINUM USITATISSIMUM (LINSEED) SEED OIL, SODIUM CHONDROITIN SULFATE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		ASCORBYL PALMITATE (VITAMIN C PALMITATE)
Not assessed for safety in cosmetics by industry panel		HYDROGENATED RAPESEED OIL, DIPENTAERYTHRITYL HEXAHYDROXYSTEARATE/HEXASTEARATE/HEXARO SINATE, CI 42090, ATELOCOLLAGEN, ACETYLATED SUCROSE DISTEARATE, TRIMETHYLOLPROPANE TRIISOSTEARATE, TRIETHYLHEXANOIN, TITANIUM DIOXIDE (NON-NANO), SUCROSE DISTEARATE, SILICA DIMETHYL SILYLATE, RHUS SUCCEDANEA (JAPANESE) WAX, VP/ EICOSENE COPOLYMER, POLYISOBUTENE, POLYETHYLENE TEREPHTHALATE, PHYTOSPHINGOSINE, PENTAERYTHRITYL TETRAISOSTEARATE, METHYL METHACRYLATE CROSSPOLYMER, LARD GLYCERIDES, ISOSTEARYL ISOSTEARATE, HYDROGENATED POLYISOBUTENE, HYDROGENATED COCO-GLYCERIDES, FRAGRANCE, ETHYLCELLULOSE, DISTEARDIMONIUM HECTORITE, DIMETHYL SILYLATE, DIISOSTEARYL MALATE, DEXTRIN PALMITATE, CITRIC ACID, CHROMIUM OXIDE GREENS, CHOLESTERYL/ BEHENYL/ OCTYLDODECYL LAUROYL GLUTAMATE, CHOLESTERYL HYDROXYSTEARATE, BIS-DIGLYCERYL POLYACYLADIPATE-2, BENZYL NICOTINATE, BARIUM SULFATE, AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), ARGININE, ALLANTOIN, ACETYLATED GLYCOL STEARATE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to moderate doses		BARIUM SULFATE
Allowed workplace exposures restricted to low doses		PARAFFIN, MICA, FERRIC FERROCYANIDE,
Allowed workplace exposures restricted to low doses		PHENOXYETHANOL
Allowed workplace exposures restricted to low doses		BHT, CHROMIUM OXIDE GREENS,
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO)
Allowed workplace exposures restricted to very low doses		CI 77491

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Interferes with gene expresion		METHYLPARABEN, BUTYLPARABEN
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood		PROPYLENE GLYCOL, LINUM USITATISSIMUM (LINSEED) SEED OIL, POLYETHYLENE, CITRIC ACID, ARGININE
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		CI 77491, BHT
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		TITANIUM DIOXIDE (NON-NANO), SILICA