

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Biochemical or cellular level changes |
Ingredients from packaging: WATER, PROPYLENE GLYCOL, PANTHENOL, RETINYL PALMITATE, TOCOPHERYL ACETATE, ALOE BARBADENSIS LEAF JUICE, PANAX GINSENG ROOT EXTRACT, CENTELLA ASIATICA EXTRACT, ROSA CANINA FRUIT EXTRACT, SPIRULINA MAXIMA EXTRACT, HYDROLYZED RICE PROTEIN, HYDROLYZED CORN PROTEIN, HYDROLYZED WHEAT PROTEIN, HYDROLYZED WHEAT STARCH, METHYL GLUCETH-10, BENZALKONIUM CHLORIDE, CETRIMONIUM CHLORIDE, DISODIUM EDTA, POLYSORBATE 20, BENZOPHENONE-4, METHYLPARABEN, DMDM HYDANTOIN, FRAGRANCE
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| DMDM HYDANTOIN | 9 | 71% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE) |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| BENZALKONIUM CHLORIDE | 7 | 62% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| RETINYL PALMITATE | 5 | 68% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| HYDROLYZED RICE PROTEIN | 4 | 99% | Contamination concerns (GOSSYPOL, HEAVY METALS, ORGANOCHLORINES, PESTICIDES) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| SULISOBENZONE (BENZOPHENONE-4) (Active Ingredient) | 3 | 66% | Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| PROPYLENE GLYCOL | 4 | 60% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| DISODIUM EDTA | 3 | 78% | Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption |
| CETRIMONIUM CHLORIDE | 3 | 71% | Allergies/immunotoxicity |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| HYDROLYZED WHEAT PROTEIN | 1 | 95% | Allergies/immunotoxicity |
| HYDROLYZED CORN PROTEIN | 1 | 94% | Multiple, additive exposure sources |
| PANAX GINSENG (GINSENG) ROOT EXTRACT PANAX GINSENG ROOT EXTRACT | 1 | 91% | none identified |
| POLYSORBATE-20 | 1 | 84% | none identified |
| ALOE BARBADENSIS (ALOE VERA) GEL ALOE BARBADENSIS LEAF JUICE | 1 | 72% | none identified |
| CENTELLA ASIATICA (GOTU KOLA) EXTRACT CENTELLA ASIATICA EXTRACT | 0 | 100% | none identified |
| HYDROLYZED WHEAT STARCH | 0 | 100% | none identified |
| ROSA CANINA (DOG ROSE) FRUIT EXTRACT ROSA CANINA FRUIT EXTRACT | 0 | 100% | none identified |
| SPIRULINA MAXIMA (ALGAE) EXTRACT SPIRULINA MAXIMA EXTRACT | 0 | 100% | none identified |
| METHYL GLUCETH-10 | 0 | 94% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not likely to be mutagenic in humans | SULISOBENZONE (BENZOPHENONE-4) | |
| One or more in vitro tests on mammalian cells show positive mutation results | PROPYLENE GLYCOL, TOCOPHERYL ACETATE, METHYLPARABEN, DISODIUM EDTA, CETRIMONIUM CHLORIDE, BENZALKONIUM CHLORIDE | |
| Cancer - limited evidence | RETINYL PALMITATE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | POLYSORBATE-20 | |
| One or more animal studies show any effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) GEL | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL | |
| One or more animal studies show reproductive effects at high doses | DISODIUM EDTA | |
| One or more animal studies show reproductive effects at low doses | RETINYL PALMITATE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PROPYLENE GLYCOL, CETRIMONIUM CHLORIDE, ALOE BARBADENSIS (ALOE VERA) GEL, BENZALKONIUM CHLORIDE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | RETINYL PALMITATE, BENZALKONIUM CHLORIDE, DMDM HYDANTOIN, BENZALKONIUM CHLORIDE | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR) | products that may be aerosolized (airborne) | DMDM HYDANTOIN |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - prohibited for use in some types of cosmetics | DMDM HYDANTOIN |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | RETINYL PALMITATE, PROPYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | METHYLPARABEN | |
| One or more animal studies show brain and nervous system effects at low doses | DISODIUM EDTA | |
| Moderate evidence of human neurotoxicity | FRAGRANCE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Associated with endocrine disruption | SULISOBENZONE (BENZOPHENONE-4) | |
| One or more animal studies show endocrine system disruption at high doses | DISODIUM EDTA | |
| Human any disruptor - strong evidence | METHYLPARABEN |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more human case studies show possible skin allergy effects | HYDROLYZED WHEAT PROTEIN | |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE, SULISOBENZONE (BENZOPHENONE-4), METHYLPARABEN, CETRIMONIUM CHLORIDE | |
| Known human immune system toxicant | FRAGRANCE, BENZALKONIUM CHLORIDE, DMDM HYDANTOIN |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | PANAX GINSENG (GINSENG) ROOT EXTRACT, POLYSORBATE-20, PANTHENOL | |
| One or more animal studies show sense effects at moderate doses (low dose studies may be unavailable for this ingredient) | SULISOBENZONE (BENZOPHENONE-4) | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | TOCOPHERYL ACETATE, DMDM HYDANTOIN, CETRIMONIUM CHLORIDE, ALOE BARBADENSIS (ALOE VERA) GEL | |
| Limited evidence of skin toxicity | RETINYL PALMITATE | |
| One or more animal studies show broad systemic effects at low doses | DISODIUM EDTA | |
| Possible human immune system toxicant | BENZALKONIUM CHLORIDE | |
| Limited evidence of respiratory toxicity | products that may be aerosolized (airborne) | PROPYLENE GLYCOL |
| Known human any toxicant | METHYLPARABEN |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | TOCOPHERYL ACETATE, RETINYL PALMITATE, PROPYLENE GLYCOL, POLYSORBATE-20, METHYLPARABEN | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL | |
| Designated as safe for general or specific, limited use in food | DISODIUM EDTA, ALOE BARBADENSIS (ALOE VERA) GEL | |
| Used in food or as an additive with limited or no toxicity information available | HYDROLYZED CORN PROTEIN |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at low doses | BENZALKONIUM CHLORIDE, METHYLPARABEN | |
| One or more animal studies show skin irritation at moderate doses | POLYSORBATE-20 | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | SULISOBENZONE (BENZOPHENONE-4), DMDM HYDANTOIN |
| Classified as skin irritant | PROPYLENE GLYCOL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL | |
| Missing safety data noted by cosmetic industry review | ALOE BARBADENSIS (ALOE VERA) GEL | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | RETINYL PALMITATE, HYDROLYZED RICE PROTEIN, METHYLPARABEN, SULISOBENZONE (BENZOPHENONE-4), TOCOPHERYL ACETATE, PANTHENOL, POLYSORBATE-20, DMDM HYDANTOIN | |
| Not assessed for safety in cosmetics by industry panel | SPIRULINA MAXIMA (ALGAE) EXTRACT, HYDROLYZED CORN PROTEIN | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | DISODIUM EDTA | |
| Not assessed for safety in cosmetics by industry panel | HYDROLYZED WHEAT PROTEIN, HYDROLYZED WHEAT STARCH, METHYL GLUCETH-10, PANAX GINSENG (GINSENG) ROOT EXTRACT, ROSA CANINA (DOG ROSE) FRUIT EXTRACT, CENTELLA ASIATICA (GOTU KOLA) EXTRACT, FRAGRANCE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Interferes with gene expresion | METHYLPARABEN | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | PANAX GINSENG (GINSENG) ROOT EXTRACT, PROPYLENE GLYCOL | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | RETINYL PALMITATE |
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