

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards |
Ingredients from packaging: ACTIVE INGREDIENTS: BENZOCAINE 20% . INACTIVE INGREDIENTS: CELLULOSE GUM, EUGENOL, BLUE #1, RED #30, OXYQUINOLINE SULFATE, PETROLATUM.
Directions from packaging: Benzodent Ointment fOR Adult Use: ONLY. + Remove cap; break metal seal with cap point. + Clean and dry dentures. + Apply directly to the gums or to the denture surface that comes in contact with the affected area of the gums. + Wait a few seconds, then reinsert dentures. + Use up to 4 times daily or as directed by a dentist. + You may use your regular denture adhesive with this product. NOTE: Consult your dentist regularly to insure proper-fitting dentures.
Warnings from packaging: Do not use for more than 7 consecutive days unless directed by a dentist. If irritation persists or inflammation, fever or infection develops, discontinue use and see your dentist immediately. Do not use if you have a history of allergy to 'caine' anesthetics. Localized allergic reactions may occur after prolonged or repeated use. KEEP OUT OF REACH OF CHILDREN. In case of accidental ingestion, seek professional assistance or contact a poison control center immediately.
| score | data gap | concerns | |
| BENZOCAINE (Active Ingredient) | 7 | 61% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| EUGENOL | 7 | 56% | Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| 8-HYDROXYQUINOLINE SULFATE | 5 | 54% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Occupational hazards |
| D&C RED 30 | 1 | 73% | Persistence and bioaccumulation |
| PETROLATUM | 2 | 94% | Organ system toxicity (non-reproductive), Contamination concerns (PAHS) |
| FD&C BLUE 1 | 1 | 83% | none identified |
| CELLULOSE GUM | 1 | 80% | none identified |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | CELLULOSE GUM | |
| One or more in vitro tests on mammalian cells show positive mutation results | 8-HYDROXYQUINOLINE SULFATE | |
| Cancer - not classifiable/not likely to be human carcinogen | FD&C BLUE 1 | |
| Not likely to be carcinogenic in humans | EUGENOL |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | CELLULOSE GUM |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | 8-HYDROXYQUINOLINE SULFATE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | 8-HYDROXYQUINOLINE SULFATE, EUGENOL | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | BENZOCAINE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | 8-HYDROXYQUINOLINE SULFATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | FD&C BLUE 1 | |
| One or more animal studies show brain and nervous system effects at low doses | EUGENOL | |
| One or more animal studies show brain and nervous system effects at high doses | BENZOCAINE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | EUGENOL, BENZOCAINE |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | PETROLATUM | |
| Persistent, bioaccumulative in wildlife | D&C RED 30 |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | CELLULOSE GUM | |
| Classified as expected to be toxic or harmful | PETROLATUM | |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | FD&C BLUE 1 | |
| One or more animal studies show cardiovascular effects at low doses | EUGENOL, 8-HYDROXYQUINOLINE SULFATE, BENZOCAINE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Prohibited for use in food | 8-HYDROXYQUINOLINE SULFATE |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at very low doses | EUGENOL | |
| One or more animal studies show skin irritation at moderate doses | BENZOCAINE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety unknown for products left on skin | products that are intended to be left on the skin | 8-HYDROXYQUINOLINE SULFATE |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | CELLULOSE GUM | |
| Not assessed for safety in cosmetics by industry panel | BENZOCAINE, EUGENOL, PETROLATUM |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | 8-HYDROXYQUINOLINE SULFATE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CELLULOSE GUM |
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