

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: Nails: ABS Plastic. Acrylic Liquid: Ethyl Methacrylate; HEMA; Glycol Dimethacrylate; Dimethyltolylamine; Benzophenone-3; p-Hydroxyanisole; CI 60725; CI 61565. Acrylic Powder: Acrylates Copolymer; Benzoyl Peroxide (Completely Evaporates After Drying); Silica. Maximum Speed Nail Glue: Ethyl Cyanoacrylate; Polymethyl Methacrylate; BHA
Warnings from packaging: EYE IRRITANT. If eye contact occurs flush immediately with water and SEE PHYSICIAN AT ONCE. Avoid glue contact with fabrics as skin burns may occur. Use in a well-ventilated area. Avoid inhalation, ingestion or prolonged contact with skin. Do not use on nails that are infected, damaged, thin or weak. Discontinue use if irritation, redness or discomfort occurs. Acrylic Liquid is flammable. Keep away from heat and flame. Store contents in dark, cool location. KEEP OUT OF REACH OF CHILDREN.
| score | data gap | concerns | |
| BHA | 10 | 49% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| OXYBENZONE (BENZOPHENONE-3) (Active Ingredient) | 9 | 55% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| HEMA | 8 | 59% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ETHYL METHACRYLATE | 8 | 57% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| SILICA | 1 | 69% | Biochemical or cellular level changes |
| HYDROXYANISOLE | 7 | 67% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| BENZOYL PEROXIDE | 7 | 55% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| ETHYL-2-CYANOACRYLATE ETHYL CYANOACRYLATE | 5 | 79% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| CI 61565 | 4 | 75% | Violations, restrictions & warnings |
| CI 60725 | 4 | 73% | Violations, restrictions & warnings |
| ACRYLIC RESIN ACRYLIC LIQUID | 4 | 72% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| ACRYLATES COPOLYMER | 3 | 75% | Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE) |
| POLYMETHYL METHACRYLATE | 1 | 89% | Organ system toxicity (non-reproductive) |
| DIMETHYLTOLYLAMINE | 2 | 83% | Organ system toxicity (non-reproductive), Occupational hazards |
| ACRYLIC POLYMER ACRYLIC POWDER | 0 | 100% | none identified |
| GLYCERYL POLYMETHACRYLATE GLYCOL DIMETHACRYLATE | 0 | 94% | none identified |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | CI 60725, OXYBENZONE (BENZOPHENONE-3) | |
| One or more in vitro tests on mammalian cells show positive mutation results | HEMA, ETHYL METHACRYLATE, DIMETHYLTOLYLAMINE, HYDROXYANISOLE, BHA | |
| Cancer - not classifiable/not likely to be human carcinogen | POLYMETHYL METHACRYLATE, BENZOYL PEROXIDE |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | BENZOYL PEROXIDE | |
| One or more animal studies show reproductive effects at high doses | HEMA, ETHYL METHACRYLATE, BHA | |
| Limited evidence of developmental toxicity | OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | HEMA, ETHYL METHACRYLATE, ACRYLATES COPOLYMER | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | HEMA | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | ETHYL METHACRYLATE, HYDROXYANISOLE, BENZOYL PEROXIDE, OXYBENZONE (BENZOPHENONE-3) | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Avoid skin contact | products for use on skin | HEMA, ETHYL METHACRYLATE |
| Violation of industry recommendations - Unsafe for use in cosmetics | HYDROXYANISOLE, HYDROXYANISOLE | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | CI 61565, BHA, CI 60725 |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | HEMA, ETHYL METHACRYLATE, OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show brain and nervous system effects at moderate doses | BHA |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - moderate evidence | OXYBENZONE (BENZOPHENONE-3) | |
| Human any disruptor - strong evidence | BHA |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of immune system toxicity | BENZOYL PEROXIDE | |
| Human skin toxicant - strong evidence | HYDROXYANISOLE | |
| Possible human photoallergenic toxicant | OXYBENZONE (BENZOPHENONE-3) | |
| Known human immune system toxicant | HEMA, ETHYL METHACRYLATE, ETHYL-2-CYANOACRYLATE, BHA, ACRYLIC RESIN |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | POLYMETHYL METHACRYLATE | |
| Persistent, bioaccumulative in wildlife | BHA | |
| Ingredient is suspected or measured to accumulate in people | OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | SILICA | |
| Classified as expected to be toxic or harmful | POLYMETHYL METHACRYLATE | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | CI 61565, CI 60725 | |
| Limited evidence of sense organ toxicity | HEMA | |
| Classified as toxic or harmful | products for use on skin; products for use around the mouth; products for use on the lips; products that may be aerosolized (airborne) | DIMETHYLTOLYLAMINE |
| One or more animal studies show broad systemic effects at low doses | BENZOYL PEROXIDE | |
| One or more animal studies show liver effects at very low doses | HYDROXYANISOLE | |
| Possible human immune system toxicant | ETHYL METHACRYLATE, ETHYL-2-CYANOACRYLATE, ACRYLIC RESIN | |
| Known human any toxicant | BHA |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | OXYBENZONE (BENZOPHENONE-3) | |
| Not suspected to be an environmental toxin | POLYMETHYL METHACRYLATE | |
| Wildlife and environmental toxicity | DIMETHYLTOLYLAMINE, BHA |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not likely to be a skin irritant in humans | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show skin irritation at very low doses | BENZOYL PEROXIDE | |
| Classified as irritant | HEMA, ETHYL METHACRYLATE, HYDROXYANISOLE, ETHYL-2-CYANOACRYLATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Considered safe based on assumption of low absorption | ACRYLATES COPOLYMER | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | OXYBENZONE (BENZOPHENONE-3) | |
| Not assessed for safety in cosmetics by industry panel | CI 61565, DIMETHYLTOLYLAMINE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | BHA | |
| Not assessed for safety in cosmetics by industry panel | ETHYL-2-CYANOACRYLATE, GLYCERYL POLYMETHACRYLATE, POLYMETHYL METHACRYLATE, CI 60725, BENZOYL PEROXIDE, ACRYLIC RESIN, ACRYLIC POLYMER |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to very low doses | BENZOYL PEROXIDE | |
| Allowed workplace exposures restricted to low doses | ETHYL-2-CYANOACRYLATE, | |
| Allowed workplace exposures restricted to low doses | DIMETHYLTOLYLAMINE, HYDROXYANISOLE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | HEMA | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SILICA, HYDROXYANISOLE, BHA |
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