Scalpicin Liquid Maximum Strength (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

SCALPICIN LIQUID MAXIMUM STRENGTH (2007 FORMULATION)

last updated: 08/15/07 brand: Scalpicin by Combe Inc.

SCORE

moderate hazard (out of 10)

73%

data gap

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14% of dandruff/scalp treatments have lower concerns
36% of anti-itch/rash creams have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption

Ingredients from packaging: Active Ingredients: Hydrocortisone Alcohol 1% ; Inactive Ingredients: SD Alcohol 40-B; Water; Propylene Glycol; Menthol; Disodium EDTA; Aloe; Coneflower Extract; Tea Tree Oil

Warnings from packaging: For external use only. When using this product: do not get into eyes. If contact occurs, rinse eyes thoroughly with water. If irritation persists, consult a doctor. Stop use of this product and do not begin use of any other hydrocortisone product if: condition worsens or if symptoms persist for more than 7 days or clear up and occur again within a few days, unless you have consulted a doctor. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Flammable.

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ingredients

	score	data gap	concerns
SD ALCOHOL 40B	4	81%	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
PROPYLENE GLYCOL	4	60%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
MENTHOL	2	85%	Multiple, additive exposure sources
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL TEA TREE OIL	1	93%	Endocrine disruption, Allergies/immunotoxicity
ECHINACEA PURPUREA (PURPLE CONEFLOWER) EXTRACT	1	90%	none identified
ALOE BARBADENSIS (ALOE VERA)	1	72%	none identified
HYDROCORTISONE ALCOHOL (Active Ingredient)	0	100%	none identified
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		PROPYLENE GLYCOL
One or more in vitro tests non-mammalian cells show positive mutation results		ALOE BARBADENSIS (ALOE VERA)
One or more in vitro tests on mammalian cells show positive mutation results		DISODIUM EDTA, MENTHOL
Cancer - limited evidence		SD ALCOHOL 40B

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		DISODIUM EDTA
One or more animal studies show reproductive effects at moderate doses		ALOE BARBADENSIS (ALOE VERA)
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL
Limited evidence of reproductive toxicity		SD ALCOHOL 40B

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		PROPYLENE GLYCOL, ALOE BARBADENSIS (ALOE VERA)

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		SD ALCOHOL 40B
One or more animal studies show brain and nervous system effects at high doses		PROPYLENE GLYCOL
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA
One or more animal studies show brain and nervous system effects at moderate doses		MENTHOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		DISODIUM EDTA, ECHINACEA PURPUREA (PURPLE CONEFLOWER) EXTRACT
Limited evidence of any disruption		MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of any toxicity		MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		PROPYLENE GLYCOL
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		MENTHOL
Limited evidence of gastrointestinal or liver toxicity		SD ALCOHOL 40B
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		PROPYLENE GLYCOL, MENTHOL, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, DISODIUM EDTA, ALOE BARBADENSIS (ALOE VERA)
Used in food or as an additive with limited or no toxicity information available		MENTHOL, SD ALCOHOL 40B

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		MENTHOL
Classified as skin irritant		PROPYLENE GLYCOL

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Safety assessment was based on related chemical		PROPYLENE GLYCOL
Missing safety data noted by cosmetic industry review		ALOE BARBADENSIS (ALOE VERA)
Not assessed for safety in cosmetics by industry panel		HYDROCORTISONE ALCOHOL, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, MENTHOL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		DISODIUM EDTA, SD ALCOHOL 40B
Not assessed for safety in cosmetics by industry panel		ECHINACEA PURPUREA (PURPLE CONEFLOWER) EXTRACT

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern

product conditions

ingredient(s)

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show blood sugar changes at high doses where the human health implications are not yet well understood		PROPYLENE GLYCOL