NEUTROGENA HEALTHY SKIN ANTI-WRINKLE CREAM, DEEP WRINKLE MOISTURIZING TREATMENT, SPF 20
last updated: 04/03/08 brand: Neutrogena by Johnson & Johnson
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29% of sunscreen: SPF 15-30s have lower concerns
39% of anti-agings have lower concerns
46% of facial moisturizer/treatments have lower concerns
COMPANY POLICIES
Compact for Safe Cosmetics
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Animal Testing Policy |
Sunscreen effectiveness* breakdown
| 5 | UVB hazard/exposure score |
| 5 | UVA hazard/exposure score |
| 0 | sunscreen instability |
*Note that the same active ingredient combination may score differently in two different products depending on the concentration of the ingredients and the mixture of inactive ingredients.
Active ingredient UV |
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 Product total |
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| AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) (2%) |
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| HOMOSALATE (7%) |
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| OCTISALATE (4%) |
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| OCTOCRYLENE (1.5%) |
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| OXYBENZONE (BENZOPHENONE-3) (2%) |
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Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used in this product: Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Note from EWG: Unlike many other kinds of personal care products, sunscreen can provide health benefits, protecting against the sun's cancer-causing UV radiation. More than one million cases of skin cancer are diagnosed in the U.S. every year. Health officials recommend wearing sunscreen as one of many important steps to minimize skin cancer risk. (more sun safety tips)
Ingredients from packaging: Active Ingredients: Avobenzone 2%; Homosalate 7%; Octisalate 4%; Octocrylene 1.5%; Oxybenzone 2% ; Inactive Ingredients: Water; Glycerin; C12-15 Alkyl Benzoate; Cetearyl Alcohol; Silica; Diethylhexyl 2,6 Napthalate; Glyceryl Stearate; PEG-100 Stearate; Caprylyl Glycol; Erythorbic Acid; Retinol; Polysorbate 20; Sodium Hyaluronate; Dimethicone; Cetearyl Glucoside; Benhenyl Alcohol; Arachidyl Glucoside; Acrylates/C10-30 Alkyl Acrylate Crosspolymer; Dipotassium Glycyrrhizate; Triethanolamine; 1,2-Hexanediol; Methylparaben; Methylisothiazolinone; Propylparaben
Directions from packaging: For external use only.Avoid contact with eyes. If product gets into eyes, rinse thoroughly with water.Discontinue use if irritation or rash appear.Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Warnings from packaging: For external use only. Avoid contact with eyes. If product gets into eyes, rinse thoroughly with water. Discontinue use if irritation or rash appear. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
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ingredients
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| OXYBENZONE (BENZOPHENONE-3) (Active Ingredient) | 9 | 55% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| SILICA | 1 | 69% | Biochemical or cellular level changes |
| PEG-100 STEARATE | 4 | 69% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| METHYLISOTHIAZOLINONE | 6 | 63% | Violations, restrictions & warnings, Allergies/immunotoxicity |
| TRIETHANOLAMINE | 6 | 58% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards |
| PROPYLPARABEN | 5 | 71% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| VITAMIN A RETINOL | 5 | 70% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| HOMOSALATE (Active Ingredient) | 4 | 74% | Violations, restrictions & warnings, Enhanced skin absorption, Contamination concerns (SALICYLIC ACID, TRIMETHYLCYCLOHEXANOL) |
| OCTISALATE (Active Ingredient) | 3 | 68% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| OCTOCRYLENE (Active Ingredient) | 3 | 71% | Violations, restrictions & warnings, Biochemical or cellular level changes |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) (Active Ingredient) | 2 | 73% | Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE) |
| C12-15 ALKYL BENZOATE | 0 | 94% | none identified |
| CETEARYL ALCOHOL | 0 | 93% | none identified |
| GLYCERYL MONOSTEARATE GLYCERYL STEARATE | 1 | 88% | none identified |
| ERYTHORBIC ACID | 1 | 87% | none identified |
| POLYSORBATE-20 | 1 | 84% | none identified |
| SODIUM HYALURONATE | 1 | 83% | none identified |
| DIPOTASSIUM GLYCYRRHIZATE | 1 | 75% | none identified |
| 1,2-HEXANEDIOL | 0 | 100% | none identified |
| ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER | 0 | 100% | none identified |
| ARACHIDYL GLUCOSIDE | 0 | 100% | none identified |
| CETEARYL GLUCOSIDE | 0 | 100% | none identified |
| DIETHYLHEXYL 2,6-NAPHTHALATE DIETHYLHEXYL 2,6 NAPTHALATE | 0 | 100% | none identified |
| CAPRYLYL GLYCOL | 0 | 94% | none identified |
| BEHENYL ALCOHOL BENHENYL ALCOHOL | 0 | 93% | none identified |
| WATER | 0 | 0% | innocuous |
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | GLYCERIN | |
| One or more in vitro tests non-mammalian cells show positive mutation results | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show tumor formation at moderate doses | PEG-100 STEARATE | |
| One or more in vitro tests on mammalian cells show positive mutation results | PROPYLPARABEN, METHYLPARABEN, ERYTHORBIC ACID, | |
| One or more in vitro tests on mammalian cells show positive mutation results | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) | |
| Cancer - limited evidence | VITAMIN A | |
| Cancer - not classifiable/not likely to be human carcinogen | TRIETHANOLAMINE |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | PEG-100 STEARATE, POLYSORBATE-20 | |
| One or more animal studies show reproductive effects at moderate doses | SODIUM HYALURONATE, GLYCERIN | |
| Limited evidence of developmental toxicity | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show reproductive effects at low doses | VITAMIN A, | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | METHYLISOTHIAZOLINONE, PEG-100 STEARATE, TRIETHANOLAMINE, DIPOTASSIUM GLYCYRRHIZATE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | VITAMIN A, METHYLISOTHIAZOLINONE, OXYBENZONE (BENZOPHENONE-3), OCTOCRYLENE, OCTISALATE, HOMOSALATE, METHYLISOTHIAZOLINONE, AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | OXYBENZONE (BENZOPHENONE-3) | |
| One or more in vitro tests on mammalian cells demonstrate neurotoxicity | METHYLISOTHIAZOLINONE | |
| One or more animal studies show brain and nervous system effects at high doses | VITAMIN A, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM HYALURONATE, METHYLPARABEN |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | TRIETHANOLAMINE | |
| One or more studies show weak endocrine disruption | HOMOSALATE | |
| One or more animal studies show endocrine system disruption at high doses | GLYCERIN | |
| Human any disruptor - moderate evidence | OXYBENZONE (BENZOPHENONE-3) | |
| Human any disruptor - strong evidence | PROPYLPARABEN, METHYLPARABEN |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human skin toxicant - strong evidence | PROPYLPARABEN | |
| Associated with immunotoxicity | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) | |
| One or more human case studies show possible immune effects | OCTISALATE | |
| Human skin toxicant - strong evidence | METHYLPARABEN | |
| Possible human photoallergenic toxicant | OXYBENZONE (BENZOPHENONE-3) | |
| Known human immune system toxicant | METHYLISOTHIAZOLINONE, TRIETHANOLAMINE |
Persistence and bioaccumulation*
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be bioaccumulative | TRIETHANOLAMINE | |
| Ingredient is suspected or measured to accumulate in people | OXYBENZONE (BENZOPHENONE-3) | |
| Found to be persistent and bioaccumulative in wildlife | OCTOCRYLENE |
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | SILICA, OCTOCRYLENE, POLYSORBATE-20, ERYTHORBIC ACID | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | OCTISALATE, GLYCERYL MONOSTEARATE, SODIUM HYALURONATE | |
| Limited evidence of skin toxicity | VITAMIN A, PEG-100 STEARATE, PROPYLPARABEN | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN | |
| Possible human immune system toxicant | TRIETHANOLAMINE | |
| Known human any toxicant | METHYLPARABEN |
Ecotoxicology*
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not suspected to be an environmental toxin | TRIETHANOLAMINE | |
| Wildlife and environmental toxicity | OXYBENZONE (BENZOPHENONE-3), OCTOCRYLENE | |
| Wildlife and environmental toxicity | PROPYLPARABEN |
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not likely to be a skin irritant in humans | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show skin irritation at moderate doses | VITAMIN A, POLYSORBATE-20, SODIUM HYALURONATE, GLYCERIN | |
| One or more animal studies show skin irritation at low doses | OCTISALATE, METHYLPARABEN | |
| One or more animal studies show skin irritation at very low doses | PEG-100 STEARATE, TRIETHANOLAMINE |
Data gaps*
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Safety assessment was based on related chemical | PEG-100 STEARATE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | PROPYLPARABEN, POLYSORBATE-20, PEG-100 STEARATE, GLYCERYL MONOSTEARATE | |
| Considered safe based on assumption of low absorption | DIPOTASSIUM GLYCYRRHIZATE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | VITAMIN A, OXYBENZONE (BENZOPHENONE-3), METHYLPARABEN, ERYTHORBIC ACID, DIMETHICONE, DIPOTASSIUM GLYCYRRHIZATE, BEHENYL ALCOHOL, CETEARYL ALCOHOL | |
| Not assessed for safety in cosmetics by industry panel | OCTOCRYLENE, OCTISALATE, HOMOSALATE, GLYCERIN, DIETHYLHEXYL 2,6-NAPHTHALATE, CETEARYL GLUCOSIDE, CAPRYLYL GLYCOL, C12-15 ALKYL BENZOATE, AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE), ARACHIDYL GLUCOSIDE, ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER, 1,2-HEXANEDIOL |
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, TRIETHANOLAMINE |
Biochemical or cellular level changes*
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Does not produces excess reactive oxygen species or other harmful biochemical changes. | OCTISALATE | |
| Interferes with gene expresion | METHYLPARABEN | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OXYBENZONE (BENZOPHENONE-3), VITAMIN A, OCTOCRYLENE | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | GLYCERIN | |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SILICA |
Copyright © 2010 by Environmental Working Group
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