ZAPZYT Acne Wash (2007 formulation) || Skin Deep: Cosmetic Safety Reviews

ZAPZYT ACNE WASH (2007 FORMULATION)

last updated: 08/15/07 brand: ZAPZYT by Waltman Pharmaceuticals

SCORE

moderate hazard (out of 10)

63%

data gap

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27% of acne treatments have lower concerns
29% of facial cleansers have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns

Ingredients from packaging: Active Ingredients: 2% Salicylic Acid ; Inactive Ingredients: Purified Water; Disodium EDTA; Chamomile Extract; Aloe Vera Gel; Bioterge AS-40; Cocamidopropyl Betaine; Glucamate DOE-120; Glydant; Sodium Chloride

Warnings from packaging: For external use only. When using this product: avoid contact with eyes. If contact occurs, flush thoroughly with water; using other topical acne medications at the same time or immediately following use of this product may increase dryness or irritation of the skin. If this occurs, only one medication should be used unless directed by a physician. Keep out of reach of children. In case of accidental ingestion, seek professional assistance or contact a Poison Control Center right away.

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ingredients

	score	data gap	concerns
DMDM HYDANTOIN GLYDANT	7	71%	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
SALICYLIC ACID (Active Ingredient)	7	66%	Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT	1	80%	Enhanced skin absorption
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	none identified
GLUCAMATE DOE-120	0	100%	none identified
SODIUM OLEFIN SULFONATE BIOTERGE AS-40	0	100%	none identified
SODIUM CHLORIDE	0	0%	innocuous
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells show positive mutation results		SODIUM CHLORIDE, DISODIUM EDTA
Cancer - not classifiable/not likely to be human carcinogen		SALICYLIC ACID

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at moderate doses		SALICYLIC ACID
One or more animal studies show reproductive effects at high doses		DISODIUM EDTA
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		SALICYLIC ACID, COCAMIDOPROPYL BETAINE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - prohibited for use in some types of cosmetics		DMDM HYDANTOIN, SALICYLIC ACID, DMDM HYDANTOIN, SALICYLIC ACID
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ALOE BARBADENSIS (ALOE VERA) GEL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show brain and nervous system effects at moderate doses		ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT
One or more animal studies show brain and nervous system effects at low doses		SALICYLIC ACID, DISODIUM EDTA

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, DISODIUM EDTA

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		DMDM HYDANTOIN, COCAMIDOPROPYL BETAINE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		SALICYLIC ACID

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		DMDM HYDANTOIN
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		ALOE BARBADENSIS (ALOE VERA) GEL
One or more animal studies show metabolic effects at low doses		SALICYLIC ACID, DISODIUM EDTA

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		SALICYLIC ACID, SODIUM CHLORIDE, ALOE BARBADENSIS (ALOE VERA) GEL, DISODIUM EDTA
Used in food or as an additive with limited or no toxicity information available		SALICYLIC ACID

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at moderate doses		SODIUM CHLORIDE, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, SALICYLIC ACID
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	DMDM HYDANTOIN

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Missing safety data noted by cosmetic industry review		ALOE BARBADENSIS (ALOE VERA) GEL
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, DMDM HYDANTOIN, DISODIUM EDTA
Not assessed for safety in cosmetics by industry panel		ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT, SODIUM OLEFIN SULFONATE, GLUCAMATE DOE-120