PREVENTIN-AT THERAPEUTIC HAND CREAM & PROTECTANT, SPF 15 (2007 FORMULATION)
last updated: 08/15/07 brand: PreVentin-AT by PreVentin-AT
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88% of sunscreen: SPF 15-30s have lower concerns
83% of anti-agings have lower concerns
84% of hand creams have lower concerns
COMPANY POLICIES
Compact for Safe Cosmetics
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Animal Testing Policy |
Sunscreen effectiveness* breakdown
| 6 | UVB hazard/exposure score |
| 8 | UVA hazard/exposure score |
| 3 | sunscreen instability |
*Note that the same active ingredient combination may score differently in two different products depending on the concentration of the ingredients and the mixture of inactive ingredients.
Active ingredient UV |
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 Product total |
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| OCTINOXATE (OCTYL METHOXYCINNAMATE) (7.5%) |
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| OCTISALATE (5%) |
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| OXYBENZONE (BENZOPHENONE-3) (2.5%) |
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Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Note from EWG: Unlike many other kinds of personal care products, sunscreen can provide health benefits, protecting against the sun's cancer-causing UV radiation. More than one million cases of skin cancer are diagnosed in the U.S. every year. Health officials recommend wearing sunscreen as one of many important steps to minimize skin cancer risk. (more sun safety tips)
Ingredients from packaging: Active Ingredients: Octinoxate 7.5%; Octisalate 5.0%; Oxybenzone 2.5% ; Inactive Ingredients: Water; Dimethicone; Hydrolyzed Soy Protein; Caprylic/Capric Triglycerides; Behenyl Alcohol; Isopentydiol; Polyglyceryl-2 Stearate; Saccharomyces/Xylitum Black Tea Ferment; Cetearyl Methicone; Glycereth 26; Ammonium Acryloyl-Dimethyltaurate/VP Copolymer; Biosaccharide Gum-1; Crambe Abyssinica Seed Oil; Limnanthes Alba (Meadowfoam) Seed Oil; Caprylic/Capric Triglyceride; Diacetyl Boldine; Glycine Soja (Soybean) Sterols; Santalum Album (Sandalwood) Extract; Phellodendron Amurense Bark Extract; Phospholipids; Linoleic Acid; Glycerin; Xanthan Gum; Tetrahexyldecyl Ascorbate; Hexylene Glycol; Caprylyl Glycol; Disodium EDTA; Hydroxyethylcellulose; Potassium Sorbate; Phenoxyethanol; Methylparaben; Ethylparaben; Butylparaben; Propylparaben; Isobutylparaben; Butylene Glycol; Avena (Oat) Kernel Extract; Phospholipids; Tocopheryl Acetate; Retinyl Palmitate; Ascorbyl Palmitate; Pentylene Glycol; Sodium Lactate; Lactic Acid; Serine; Sorbitol; Sodium Chloride; Allantoin
Warnings from packaging: For topical use only. Avoid contact with eyes. If product gets into eyes, flush immediately with warm water. Discontinue use if signs of irritation or rash appear. Not for use by individuals under the age of 18 unless directed by doctor. Use only as directed. Keep out of the reach of children.
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ingredients
| score | data gap | concerns | |
| METHYLPARABEN | 10 | 63% | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| OXYBENZONE (BENZOPHENONE-3) (Active Ingredient) | 9 | 55% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| OCTINOXATE (OCTYL METHOXYCINNAMATE) (Active Ingredient) | 6 | 65% | Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| BUTYLPARABEN | 6 | 79% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| ETHYLPARABEN | 5 | 80% | Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| PROPYLPARABEN | 5 | 71% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| LACTIC ACID | 4 | 70% | Violations, restrictions & warnings, Irritation (skin, eyes, or lungs) |
| RETINYL PALMITATE | 5 | 68% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| HEXYLENE GLYCOL | 4 | 67% | Allergies/immunotoxicity, Irritation (skin, eyes, or lungs) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| SODIUM LACTATE | 4 | 70% | Violations, restrictions & warnings |
| OCTISALATE (Active Ingredient) | 3 | 68% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| PHENOXYETHANOL | 4 | 67% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards |
| ISOBUTYLPARABEN | 3 | 83% | Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| DISODIUM EDTA | 3 | 78% | Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| CAPRYLIC/ CAPRIC TRIGLYCERIDE | 0 | 94% | none identified |
| LINOLEIC ACID | 1 | 93% | Irritation (skin, eyes, or lungs) |
| PENTYLENE GLYCOL | 1 | 89% | none identified |
| ASCORBYL PALMITATE (VITAMIN C PALMITATE) | 1 | 88% | none identified |
| SORBITOL | 1 | 88% | none identified |
| POTASSIUM SORBATE | 1 | 85% | none identified |
| HYDROXYETHYLCELLULOSE | 1 | 82% | none identified |
| BUTYLENE GLYCOL | 1 | 79% | Irritation (skin, eyes, or lungs) |
| AMMONIUM ACRYLOYLDIMETHYL TAURATE/ VP COPOLYMER | 0 | 100% | none identified |
| AVENA SATIVA (OAT) KERNEL EXTRACT AVENA (OAT) KERNEL EXTRACT | 0 | 100% | none identified |
| GLYCINE SOJA (SOYBEAN) STEROLS | 0 | 100% | none identified |
| ISOPENTYLDIOL ISOPENTYDIOL | 0 | 100% | none identified |
| PHELLODENDRON AMURENSE (AMUR CORK TREE) BARK EXTRACT PHELLODENDRON AMURENSE BARK EXTRACT | 0 | 100% | none identified |
| PHOSPHOLIPIDS | 0 | 100% | none identified |
| SANTALUM ALBUM (SANDALWOOD) EXTRACT | 0 | 100% | none identified |
| TETRAHEXYLDECYL ASCORBATE | 0 | 100% | none identified |
| BIOSACCHARIDE GUM-1 | 0 | 100% | none identified |
| CRAMBE ABYSSINICA SEED OIL | 0 | 100% | none identified |
| DIACETYL BOLDINE | 0 | 100% | none identified |
| LIMNANTHES ALBA (MEADOWFOAM) SEED OIL | 0 | 100% | none identified |
| POLYGLYCERYL-2 STEARATE | 0 | 100% | none identified |
| CETEARYL METHICONE | 0 | 99% | none identified |
| ALLANTOIN | 0 | 94% | none identified |
| CAPRYLYL GLYCOL | 0 | 94% | none identified |
| GLYCERETH-26 | 0 | 94% | none identified |
| HYDROLYZED GLYCINE SOJA (SOY) PROTEIN HYDROLYZED SOY PROTEIN | 0 | 94% | none identified |
| SERINE | 0 | 94% | none identified |
| XANTHAN GUM | 0 | 94% | none identified |
| BEHENYL ALCOHOL | 0 | 93% | none identified |
| SACCHAROMYCES/XYLINUM BLACK TEA FERMENT SACCHAROMYCES/XYLITUM BLACK TEA FERMENT | 0 | 93% | none identified |
| SODIUM CHLORIDE | 0 | 0% | innocuous |
| WATER | 0 | 0% | innocuous |
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | PHENOXYETHANOL, OXYBENZONE (BENZOPHENONE-3) | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, SORBITOL, SODIUM CHLORIDE, PROPYLPARABEN, POTASSIUM SORBATE, METHYLPARABEN, GLYCERIN, ETHYLPARABEN, DISODIUM EDTA, BUTYLPARABEN | |
| Cancer - not classifiable/not likely to be human carcinogen | SODIUM LACTATE, LACTIC ACID | |
| Cancer - limited evidence | RETINYL PALMITATE |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | HYDROXYETHYLCELLULOSE, ETHYLPARABEN, DISODIUM EDTA, BUTYLENE GLYCOL | |
| One or more animal studies show reproductive effects at moderate doses | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN | |
| Limited evidence of developmental toxicity | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show reproductive effects at low doses | RETINYL PALMITATE, | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN | |
| One or more animal studies show any effects at very low doses | BUTYLPARABEN |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LACTATE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | LACTIC ACID | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | RETINYL PALMITATE, LACTIC ACID, OXYBENZONE (BENZOPHENONE-3), OCTISALATE, PHENOXYETHANOL | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits | SODIUM LACTATE, LACTIC ACID | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | HEXYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at high doses | SODIUM LACTATE, RETINYL PALMITATE, POTASSIUM SORBATE, PENTYLENE GLYCOL, OXYBENZONE (BENZOPHENONE-3), LACTIC ACID, HYDROXYETHYLCELLULOSE, GLYCERIN, BUTYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | PHENOXYETHANOL, METHYLPARABEN | |
| One or more animal studies show brain and nervous system effects at low doses | DISODIUM EDTA |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | HEXYLENE GLYCOL, GLYCERIN, DISODIUM EDTA | |
| One or more animal studies show endocrine disruption at moderate doses | SODIUM LACTATE | |
| Human any disruptor - moderate evidence | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show endocrine system disruption at high doses | BUTYLENE GLYCOL | |
| One or more animal studies show endocrine disruption at moderate doses | ISOBUTYLPARABEN | |
| Human any disruptor - strong evidence | PROPYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), METHYLPARABEN, ETHYLPARABEN, BUTYLPARABEN |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PHENOXYETHANOL | |
| One or more human case studies show possible photoallergic effects | OCTINOXATE (OCTYL METHOXYCINNAMATE), OCTISALATE | |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN, ISOBUTYLPARABEN, ETHYLPARABEN | |
| Known human immune system toxicant | HEXYLENE GLYCOL | |
| Possible human photoallergenic toxicant | OXYBENZONE (BENZOPHENONE-3) | |
| Human skin toxicant - strong evidence | BUTYLPARABEN |
Persistence and bioaccumulation*
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient is suspected or measured to accumulate in people | OXYBENZONE (BENZOPHENONE-3), OCTINOXATE (OCTYL METHOXYCINNAMATE) |
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | HEXYLENE GLYCOL, SORBITOL, HYDROXYETHYLCELLULOSE, SODIUM LACTATE, PENTYLENE GLYCOL, BUTYLENE GLYCOL, ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient) | PHENOXYETHANOL, | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | TOCOPHERYL ACETATE, POTASSIUM SORBATE, OCTISALATE, LINOLEIC ACID | |
| Limited evidence of skin toxicity | RETINYL PALMITATE | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | LACTIC ACID | |
| Limited evidence of sense organ toxicity | PROPYLPARABEN, ISOBUTYLPARABEN, ETHYLPARABEN, BUTYLPARABEN | |
| One or more animal studies show broad systemic effects at low doses | DISODIUM EDTA | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN | |
| Known human any toxicant | METHYLPARABEN |
Ecotoxicology*
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | OXYBENZONE (BENZOPHENONE-3), OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Wildlife and environmental toxicity | PROPYLPARABEN |
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not likely to be a skin irritant in humans | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show skin irritation at high doses | PENTYLENE GLYCOL | |
| One or more animal studies show skin irritation at moderate doses | SODIUM CHLORIDE, GLYCERIN, BUTYLPARABEN | |
| One or more animal studies show skin irritation at low doses | OCTISALATE, METHYLPARABEN, LINOLEIC ACID | |
| One or more animal studies show skin irritation at very low doses | LACTIC ACID | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | BUTYLENE GLYCOL |
| Classified as irritant | PHENOXYETHANOL, HEXYLENE GLYCOL |
Data gaps*
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOCOPHERYL ACETATE | |
| Safety assessment was based on related chemical | ISOBUTYLPARABEN, CETEARYL METHICONE | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | RETINYL PALMITATE, PROPYLPARABEN, OXYBENZONE (BENZOPHENONE-3), PHENOXYETHANOL, POTASSIUM SORBATE, METHYLPARABEN, ETHYLPARABEN, HEXYLENE GLYCOL, HYDROXYETHYLCELLULOSE, DISODIUM EDTA, DIMETHICONE, CETEARYL METHICONE, BUTYLPARABEN, BEHENYL ALCOHOL, BUTYLENE GLYCOL | |
| Not assessed for safety in cosmetics by industry panel | LIMNANTHES ALBA (MEADOWFOAM) SEED OIL, POLYGLYCERYL-2 STEARATE, SACCHAROMYCES/XYLINUM BLACK TEA FERMENT | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| Not assessed for safety in cosmetics by industry panel | DIACETYL BOLDINE, CRAMBE ABYSSINICA SEED OIL, BIOSACCHARIDE GUM-1, XANTHAN GUM, TETRAHEXYLDECYL ASCORBATE, SORBITOL, SERINE, SANTALUM ALBUM (SANDALWOOD) EXTRACT, PHOSPHOLIPIDS, PHELLODENDRON AMURENSE (AMUR CORK TREE) BARK EXTRACT, PENTYLENE GLYCOL, OCTISALATE, LINOLEIC ACID, ISOPENTYLDIOL, HYDROLYZED GLYCINE SOJA (SOY) PROTEIN, GLYCINE SOJA (SOYBEAN) STEROLS, GLYCERIN, GLYCERETH-26, CAPRYLYL GLYCOL, CAPRYLIC/ CAPRIC TRIGLYCERIDE, AVENA SATIVA (OAT) KERNEL EXTRACT, AMMONIUM ACRYLOYLDIMETHYL TAURATE/ VP COPOLYMER, ALLANTOIN |
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| No workplace limits set | LACTIC ACID | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN | |
| Allowed workplace exposures restricted to low doses | PHENOXYETHANOL |
Biochemical or cellular level changes*
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Does not produces excess reactive oxygen species or other harmful biochemical changes. | OCTISALATE | |
| Interferes with gene expresion | METHYLPARABEN, BUTYLPARABEN | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OCTINOXATE (OCTYL METHOXYCINNAMATE), RETINYL PALMITATE, OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | GLYCERIN |
Copyright © 2010 by Environmental Working Group
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